Results 31 to 40 of about 10,304,482 (352)
Proceedings of the National Academy of Sciences of the United States of America, 2002 Integration of synaptic excitation to generate an action potential (excitatory postsynaptic potential-spike coupling or E-S coupling) determines the neuronal output.
Gaël Daoudal, Y. Hanada, D. Debanne
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Proceedings of the National Academy of Sciences of the United States of America, 1991 The original proposal that substance P is involved in the regulation of nociceptive information at the first sensory synapse in the spinal cord has been substantiated by a wide range of evidence, but definitive support has been lacking, due primarily to ...
Y. de Koninck, J. Henry
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Entropy, 2019 The human postsynaptic density is an elaborate network comprising thousands of proteins, playing a vital role in the molecular events of learning and the formation of memory.
Annamária Kiss-Tóth +6 more
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Electrogenesis of the slow inhibitory postsynaptic potential in bullfrog sympathetic ganglia.
The Japanese Journal of Physiology, 1983 The ionic mechanisms of the slow surface positive (P)-potential and the slow inhibitory postsynaptic potential (IPSP), an intracellularly recorded P-potential in sympathetic ganglia, were analysed by means of sucrose-gap, intracellular microelectrode ...
T. Akasu, K. Koketsu
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GABAergic synaptic transmission regulates calcium influx during spike-timing dependent plasticity
Frontiers in Synaptic Neuroscience, 2010 Coincident pre- and postsynaptic activity of hippocampal neurons alters the strength of gamma-aminobutyric acid (GABAA)-mediated inhibition through a Ca2+-dependent regulation of cation-chloride cotransporters.
Trevor Balena +2 more
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Differential Effects of D-Cycloserine and ACBC at NMDA Receptors in the Rat Entorhinal Cortex Are Related to Efficacy at the Co-Agonist Binding Site. [PDF]
PLoS ONE, 2015 Partial agonists at the NMDA receptor co-agonist binding site may have potential therapeutic efficacy in a number of cognitive and neurological conditions. The entorhinal cortex is a key brain area in spatial memory and cognitive processing.
Alex M Lench +2 more
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Event-based update of synapses in voltage-based learning rules [PDF]
, 2020 Due to the point-like nature of neuronal spiking, efficient neural network simulators often employ event-based simulation schemes for synapses. Yet many types of synaptic plasticity rely on the membrane potential of the postsynaptic cell as a third factor in addition to pre- and postsynaptic spike times.
arxiv +1 more source
Human synapses show a wide temporal window for spike-timing-dependent plasticity
Frontiers in Synaptic Neuroscience, 2010 Throughout our lifetime, activity-dependent changes in neuronal connection strength enable the brain to refine neural circuits and learn based on experience.
Guilherme T Silva +7 more
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Neuromodulation of Chemical Synaptic Transmission Driven by THz Photons
Research, 2022 Postsynaptic currents of chemical synapse are modulated by multitudinous neurotransmitters, such as acetylcholine, dopamine, glutamate, and γ-aminobutyric acid, many of which have been used in the treatment of neurological diseases.
Xiaoxuan Tan +3 more
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Paradoxical Results of Long-Term Potentiation explained by Voltage-based Plasticity Rule [PDF]
Front. Synaptic Neurosci. (2020) 12:585539, 2020 Experiments have shown that the same stimulation pattern that causes Long-Term Potentiation in proximal synapses, will induce Long-Term Depression in distal ones. In order to understand these, and other, surprising observations we use a phenomenological model of Hebbian plasticity at the location of the synapse.
arxiv +1 more source