Results 11 to 20 of about 65,085 (300)
VKCDB: Voltage-gated potassium channel database [PDF]
BMC Bioinformatics, 2004 Background The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based component of the membrane potential and are thus central to many critical ...
Gallin Warren J, Li Bin
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Mechanism of electromechanical coupling in voltage-gated potassium channels [PDF]
Frontiers in Pharmacology, 2012 Voltage-gated ion channels play a central role in the generation of action potentials in the nervous system. They are selective for one type of ion – sodium, calcium or potassium. Voltage-gated ion channels are composed of a central pore that allows ions
Rikard eBlunck +3 more
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KCNQs: Ligand- and Voltage-Gated Potassium Channels [PDF]
Frontiers in Physiology, 2020 Voltage-gated potassium (Kv) channels in the KCNQ (Kv7) family are essential features of a broad range of excitable and non-excitable cell types and are found in organisms ranging from Hydra vulgaris to Homo sapiens.
Geoffrey W. Abbott
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The role of axonal voltage-gated potassium channels in tDCS
Brain Stimulation, 2022 Background: Transcranial direct current stimulation (tDCS) is a non-invasive sub-threshold stimulation, widely accepted for its amelioration of distinct neuropsychiatric disorders.
Sreerag Othayoth Vasu, Hanoch Kaphzan
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Voltage-Gated Potassium Channels as Regulators of Cell Death [PDF]
Frontiers in Cell and Developmental Biology, 2020 Ion channels allow the flux of specific ions across biological membranes, thereby determining ion homeostasis within the cells. Voltage-gated potassium-selective ion channels crucially contribute to the setting of the plasma membrane potential, to volume
Magdalena Bachmann +9 more
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Voltage-gated potassium channels and genetic epilepsy
Frontiers in NeurologyRecent advances in exome and targeted sequencing have significantly improved the aetiological diagnosis of epilepsy, revealing an increasing number of epilepsy-related pathogenic genes.
Yiting Zheng, Jing Chen
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Pharmacological Actions of Potassium Channel Openers on Voltage-Gated Potassium Channels
PharmaceuticalsBackground/Objectives: Potassium (K+) channels are essential transmembrane proteins that regulate ion flow, playing a critical role in regulating action potentials and neuronal transmission.
Michael T. McCoy +3 more
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Modeling the kinetics of heteromeric potassium channels
Frontiers in Cellular Neuroscience, 2022 Mechanistic mathematical modeling has long been used as a tool for answering questions in cellular physiology. To mathematically describe cellular processes such as cell excitability, volume regulation, neurotransmitter release, and hormone secretion ...
Kees McGahan, James Keener
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Mechanisms of Activation of Voltage-Gated Potassium Channels [PDF]
Acta Naturae, 2014 Voltage-gated potassium ion channels (Kv) play an important role in a variety of cellular processes, including the functioning of excitable cells, regulation of apoptosis, cell growth and differentiation, the release of neurotransmitters and hormones, maintenance of cardiac activity, etc.
GRIZEL A.V., GLUKHOV G.S., SOKOLOVA O.S.
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Functional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles. [PDF]
PLoS ONE, 2011 Voltage-gated ion channels are key players in cellular excitability. Recent studies suggest that their behavior can depend strongly on the membrane lipid composition and physical state. In vivo studies of membrane/channel and channel/channel interactions
Sophie Aimon +5 more
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