Results 11 to 20 of about 1,844,829 (280)
VKCDB: Voltage-gated potassium channel database [PDF]
BMC Bioinformatics, 2004 Background The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based component of the membrane potential and are thus central to many critical ...
Gallin Warren J, Li Bin
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Mechanism of electromechanical coupling in voltage-gated potassium channels [PDF]
Frontiers in Pharmacology, 2012 Voltage-gated ion channels play a central role in the generation of action potentials in the nervous system. They are selective for one type of ion – sodium, calcium or potassium. Voltage-gated ion channels are composed of a central pore that allows ions
Rikard eBlunck +3 more
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KCNQs: Ligand- and Voltage-Gated Potassium Channels [PDF]
Frontiers in Physiology, 2020 Voltage-gated potassium (Kv) channels in the KCNQ (Kv7) family are essential features of a broad range of excitable and non-excitable cell types and are found in organisms ranging from Hydra vulgaris to Homo sapiens.
Geoffrey W. Abbott
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Extended secondhand smoke exposure alters potassium channel activity and reduces excitability of cardiac vagal neurons in mice [PDF]
Frontiers in PhysiologyBackgroundDespite the decline in secondhand smoke (SHS) exposure since the implementation of smoking bans in public places, SHS exposure remains a significant health risk factor affecting about 1/3 of non-smokers worldwide.
Junqing Sun +4 more
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Voltage-gated potassium channels and genetic epilepsy
Frontiers in NeurologyRecent advances in exome and targeted sequencing have significantly improved the aetiological diagnosis of epilepsy, revealing an increasing number of epilepsy-related pathogenic genes.
Yiting Zheng, Jing Chen
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Direct neurotransmitter activation of voltage-gated potassium channels [PDF]
Nature Communications, 2018 M-current is conveyed by voltage-sensitive KCNQ channels, which are enriched in GABAergic neurons and are activated by anticonvulsants such as retigabine.
Rían W. Manville +2 more
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Voltage-Dependent Ion Channels in Vascular Endothelial Cells: An Unexpected Signaling Pathway in Non-Excitable Cells [PDF]
BiomedicinesVoltage-gated ion channels (VGICs) are traditionally associated with electrically excitable cells; however, increasing evidence indicates that they are also expressed in non-excitable cells, including vascular endothelial cells.
Francesco Moccia, Teresa Soda
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Pharmacological Actions of Potassium Channel Openers on Voltage-Gated Potassium Channels
PharmaceuticalsBackground/Objectives: Potassium (K+) channels are essential transmembrane proteins that regulate ion flow, playing a critical role in regulating action potentials and neuronal transmission.
Michael T. McCoy +3 more
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Structure and function of potassium and calcium channels [PDF]
, 2005 In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
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Frontiers in Cellular Neuroscience, 2017 Neurons are highly polarized cells with apparent functional and morphological differences between dendrites and axon. A critical determinant for the molecular and functional identity of axonal and dendritic segments is the restricted expression of ...
Jeffrey Lopez-Rojas +4 more
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