Results 21 to 30 of about 1,844,829 (280)
The role of axonal voltage-gated potassium channels in tDCS
Brain Stimulation, 2022 Background: Transcranial direct current stimulation (tDCS) is a non-invasive sub-threshold stimulation, widely accepted for its amelioration of distinct neuropsychiatric disorders.
Sreerag Othayoth Vasu, Hanoch Kaphzan
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Drug binding sites on Nat1.8 sodium channels [PDF]
, 2008 The voltage-gated sodium channel, Nav 1.8, is known to play an important role in pain signalling. In this thesis, the functional properties and drug binding sites of wild type and mutant Nav 1.8 sodium channel currents were studied in mammalian sensory ...
Browne, Liam Edward
core +6 more sources
Modeling the kinetics of heteromeric potassium channels
Frontiers in Cellular Neuroscience, 2022 Mechanistic mathematical modeling has long been used as a tool for answering questions in cellular physiology. To mathematically describe cellular processes such as cell excitability, volume regulation, neurotransmitter release, and hormone secretion ...
Kees McGahan, James Keener
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Mechanisms of Activation of Voltage-Gated Potassium Channels [PDF]
Acta Naturae, 2014 Voltage-gated potassium ion channels (Kv) play an important role in a variety of cellular processes, including the functioning of excitable cells, regulation of apoptosis, cell growth and differentiation, the release of neurotransmitters and hormones, maintenance of cardiac activity, etc.
GRIZEL A.V., GLUKHOV G.S., SOKOLOVA O.S.
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Functional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles. [PDF]
PLoS ONE, 2011 Voltage-gated ion channels are key players in cellular excitability. Recent studies suggest that their behavior can depend strongly on the membrane lipid composition and physical state. In vivo studies of membrane/channel and channel/channel interactions
Sophie Aimon +5 more
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Heliyon, 2023 Osteoarthritis (OA) is one of the leading causes of chronic pain and dysfunction. It is essential to comprehend the nature of pain and cartilage degeneration and its influencing factors on OA treatment. Voltage-gated ion channels (VGICs) are essential in
Xinwei Wang, Xueping Li
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Role of Kv1 potassium channels in regulating dopamine release and presynaptic D2 receptor function. [PDF]
PLoS ONE, 2011 Dopamine (DA) release in the CNS is critical for motor control and motivated behaviors. Dysfunction of its regulation is thought to be implicated in drug abuse and in diseases such as schizophrenia and Parkinson's.
Philippe Martel +4 more
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Voltage-Gated Potassium Channels as Regulators of Cell Death
Frontiers in Cell and Developmental Biology, 2020 Ion channels allow the flux of specific ions across biological membranes, thereby determining ion homeostasis within the cells. Voltage-gated potassium-selective ion channels crucially contribute to the setting of the plasma membrane potential, to volume
Magdalena Bachmann +9 more
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Oxidative Modulation of Voltage-Gated Potassium Channels [PDF]
Antioxidants & Redox Signaling, 2014 Significance: Voltage-gated K + channels are a large family of K + -selective ion channel protein complexes that open on membrane depolarization. These K +
Nirakar, Sahoo +2 more
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KCNE1 and KCNE2 provide a checkpoint governing voltage-gated potassium channel α-subunit composition [PDF]
, 2011 Voltage-gated potassium (Kv) currents generated by N-type α-subunit homotetramers inactivate rapidly because an N-terminal ball domain blocks the channel pore after activation.
Abbott, G. +12 more
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