Results 21 to 30 of about 171,305 (316)

Photocontrol of Voltage-Gated Ion Channel Activity by Azobenzene Trimethylammonium Bromide in Neonatal Rat Cardiomyocytes. [PDF]

open access: yesPLoS ONE, 2016
The ability of azobenzene trimethylammonium bromide (azoTAB) to sensitize cardiac tissue excitability to light was recently reported. The dark, thermally relaxed trans- isomer of azoTAB suppressed spontaneous activity and excitation propagation speed ...
Sheyda R Frolova   +4 more
doaj   +1 more source

The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. [PDF]

open access: yes, 2011
The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death.
Anish Bali   +6 more
core   +5 more sources

Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]

open access: yes, 1990
In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S.   +3 more
core   +1 more source

Implication of Voltage-Gated Potassium Channels in Neoplastic Cell Proliferation

open access: yesCancers, 2019
Voltage-gated potassium channels (Kv) are the largest group of ion channels. Kv are involved in controlling the resting potential and action potential duration in the heart and brain.
Clara Serrano-Novillo   +5 more
semanticscholar   +1 more source

Activity of Palythoa caribaeorum Venom on Voltage-Gated Ion Channels in Mammalian Superior Cervical Ganglion Neurons

open access: yesToxins, 2016
The Zoanthids are an order of cnidarians whose venoms and toxins have been poorly studied. Palythoa caribaeorum is a zoanthid commonly found around the Mexican coastline. In this study, we tested the activity of P.
Fernando Lazcano-Pérez   +5 more
doaj   +1 more source

A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels

open access: yesMarine Drugs, 2022
Sea anemones are a rich source of biologically active compounds. Among approximately 1100 species described so far, Heteractis crispa species, also known as sebae anemone, is native to the Indo-Pacific area.
Ernesto Lopes Pinheiro-Junior   +5 more
doaj   +1 more source

Lipid ion channels and the role of proteins [PDF]

open access: yes, 2013
Synthetic lipid membranes in the absence of proteins can display quantized conduction events for ions that are virtually indistinguishable from those of protein channel. By indistinguishable we mean that one cannot decide based on the current trace alone
Heimburg, Thomas, Mosgaard, Lars D.
core   +1 more source

Ion channel gating: a first passage time analysis of the Kramers type [PDF]

open access: yes, 2001
The opening rate of voltage-gated potassium ion channels exhibits a characteristic, knee-like turnover where the common exponential voltage-dependence changes suddenly into a linear one.
Blatz   +12 more
core   +4 more sources

Photochromic Blockers of Voltage‐Gated Potassium Channels [PDF]

open access: yesAngewandte Chemie International Edition, 2009
Photochromic ligands (PCLs) can be optically switchedbetween isomers that show different biological activities. Assuch, they offer an opportunity to convert ligand-actuatedpathways into light-actuated pathways, thus making it possi-ble to control a wide range of biological processes with light.PCLs have been explored for various classes of ...
Matthew R, Banghart   +5 more
openaire   +2 more sources

Functional Coupling of Cav2.3 and BK Potassium Channels Regulates Action Potential Repolarization and Short-Term Plasticity in the Mouse Hippocampus

open access: yesFrontiers in Cellular Neuroscience, 2019
Voltage-gated ion channels are essential for signal generation and propagation in neurons and other excitable cells. The high-voltage activated calcium-channel Cav2.3 is expressed throughout the central and peripheral nervous system, and within CA1 ...
Jakob J. Gutzmann   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy