Results 41 to 50 of about 7,289 (180)

Vaccinia Virus Attenuation by Codon Deoptimization of the A24R Gene for Vaccine Development

Microbiology Spectrum, 2022
Poxviruses have large DNA genomes, and they are able to infect multiple vertebrate and invertebrate animals, including humans. Despite the eradication of smallpox, poxvirus infections still remain a significant public health concern.
María M. Lorenzo, Aitor Nogales, Kevin Chiem, Rafael Blasco, Luis Martínez-Sobrido   +4 more
doaj   +1 more source

Ophthalmic manifestations of monkeypox infection

Indian Journal of Ophthalmology, 2023
After the global COVID-19 pandemic, there has been an alarming concern with the monkeypox (mpox) outbreak, which has affected more than 110 countries worldwide. Monkeypox virus is a doublestranded DNA virus of the genus Orthopox of the Poxviridae family,
Bharat Gurnani, Kirandeep Kaur, Sameer Chaudhary, Harinikrishna Balakrishnan   +3 more
doaj   +1 more source

Clinical signs, diagnosis, and case reports of Vaccinia virus infections

Brazilian Journal of Infectious Diseases
Vaccinia virus is responsible for a zoonosis that usually affects cattle and human beings in Brazil. The initial clinical signs of the infection are focal red skin areas, fever, and general symptoms similar to those of a cold.
Daniela Carla Medeiros Silva, Eduardo Augusto dos Santos Moreira-Silva, Juliana de Assis Silva Gomes, Flávio Guimarães da Fonseca, Rodrigo Correa-Oliveira   +4 more
doaj   +1 more source

Poxviruses in Bats … so What?

Viruses, 2014
Poxviruses are important pathogens of man and numerous domestic and wild animal species. Cross species (including zoonotic) poxvirus infections can have drastic consequences for the recipient host.
Kate S. Baker, Pablo R. Murcia
doaj   +1 more source

Small Hero with Great Powers: Vaccinia Virus E3 Protein and Evasion of the Type I IFN Response

Biomedicines, 2022
Poxviridae have developed a plethora of strategies to evade innate and adaptive immunity. In this review, we focused on the vaccinia virus E3 protein, encoded by the E3L gene. E3 is present within the Chordopoxvirinae subfamily (with the exception of the
Mateusz Szczerba, Sambhavi Subramanian, Kelly Trainor, Megan McCaughan, Karen V. Kibler, Bertram L. Jacobs   +5 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Clinical and epidemiological evolution of sheep pox in Morocco [PDF]

, 2019
Sheep pox is an infectious viral disease that affects specifically sheep and it is caused by the Capripoxvirus genus. The clinical signs include fever, diarrhea, difficulty breathing, nodules, lung lesions and death.
De Clercq, Kris, Ennaji, Mustapha, Haegeman, Andy, Khayli, Mounir, Lafar, Sara, Lancelot, Renaud, Zro, Khalil   +6 more
core   +1 more source

Clinical and computed tomography findings of fatal poxviral vasculitis in a domestic shorthair cat

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This report describes the clinical presentation, haematological abnormalities and imaging findings of systemic poxvirus infection in a cat that resulted in widespread severe dermal oedema and systemic inflammatory response syndrome. The cat lacked cutaneous lesions before the onset of dermal oedema, but developed crusting skin lesions and a ...
Mica Taylor, Harriet R. Hall, Hannah Wong, Lorraine Peschard, Emanuele Ricci, Katie E. McCallum   +5 more
wiley   +1 more source

Orthopoxvirus DNA in Eurasian Lynx, Sweden [PDF]

, 2011
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe.
af Segerstad, C.H., Morner, T., Okeke, M. I., Ryser-Degiorgis, Marie-Pierre, Traavik, T., Tryland, M.   +5 more
core   +4 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source