A System Based-Approach to Examine Cytokine Response in Poxvirus-Infected Macrophages
The poxviruses are large, linear, double-stranded DNA viruses about 130 to 230 kbp, that have an animal origin and evolved to infect a wide host range.
Pui-San Wong +5 more
doaj +1 more source
ABSTRACT Background and Aims Severe fever with thrombocytopenia syndrome virus (SFTSV) infection causes profound dysregulation of humoral immunity, leading to immunopathology and impaired viral clearance. However, the mechanisms underlying B cell dysfunction and inadequate antibody responses remain poorly defined.
Hongyan Hou +5 more
wiley +1 more source
Genome Variability and Gene Content in Chordopoxviruses: Dependence on Microsatellites
To investigate gene loss in poxviruses belonging to the Chordopoxvirinae subfamily, we assessed the gene content of representative members of the subfamily, and determined whether individual genes present in each genome were intact, truncated, or ...
Eneida L. Hatcher +2 more
doaj +1 more source
Host-derived pathogenicity islands in poxviruses
Background Poxviruses are important both as pathogens and as vaccine vectors. Poxvirus genomes (150–350 kb) consist of a single linear dsDNA molecule; the two polynucleotide strands are joined by short hairpin loops.
Upton Chris, Da Silva Melissa
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Dermatoses of nipple as molluscum contagiosum – Clinical dilemma
Molluscum contagiosum is a very common skin and mucosal disease of viral origin, caused by molluscum contagiosum virus (MCV) 0 of poxvirus family. With the eradication of smallpox, MCV is the only member of the poxvirus family that causes substantial ...
Puneet K Agarwal, Chirag S Dausage
doaj +1 more source
Impact of Distinct Poxvirus Infections on the Specificities and Functionalities of CD4+T Cell Responses [PDF]
Nicholas A. Siciliano +7 more
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Berlin Squirrelpox Virus, a New Poxvirus in Red Squirrels, Berlin, Germany
Near Berlin, Germany, several juvenile red squirrels (Sciurus vulgaris) were found with moist, crusty skin lesions. Histology, electron microscopy, and cell culture isolation revealed an orthopoxvirus-like infection.
Gudrun Wibbelt +5 more
doaj +1 more source
Discovery of small molecule inhibitors of ubiquitin-like poxvirus proteinase I7L using homology modeling and covalent docking approaches [PDF]
Vsevolod Katritch +8 more
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Infection with Possible Novel Parapoxvirus in Horse, Finland, 2013
A horse in Finland exhibited generalized granulomatous inflammation and severe proliferative dermatitis. After euthanization, we detected poxvirus DNA from a skin lesion sample.
Niina Airas +9 more
doaj +1 more source
Structural Basis for Targeting of Human RNA Helicase DDX3 by Poxvirus Protein K7 [PDF]
Shun-ichiro Oda +2 more
openalex +1 more source

