Results 101 to 110 of about 74,506 (264)
A PPARγ transzkripciós célpontjai M2 makrofágokban
, 2017 One of the key cell types behind both the acute and resolution phase of inflammation is the macrophage. However, the roles and functions of macrophages are diverse and sometimes opposing in different phases of inflammation.
Papp, Csaba
core
Analysis of PPARγ Signaling Activity in Psoriasis
, 2021 In our previous work, we built the model of PPARγ dependent pathways involved in the development of the psoriatic lesions. Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor and transcription factor which regulates the ...
Alexandre Mezentsev +8 more
core +1 more source
AgriFood: Journal of Agricultural Products for Food, EarlyView.The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang +6 more
wiley +1 more source
Identification of intermediate filament protein vimentin as an interacting protein of PPARγ
, 2010 過氧化體增殖劑活化受體γ (PPARgamma)是nuclear receptor家族中受配體(ligand)調控而活化的轉錄因子，它調控了參與分化、新陳代謝和免疫反應的基因表現。配體對PPARγ的結合使得轉錄輔抑制子脫離，並促使轉錄輔活化子返回與PPARγ結合進而活化基因轉錄的進行。PPARγ是信息傳遞的中樞因子，它的活性在不同的胞內運作機制下受到很完善的調控。致裂原(mitogen)的刺激會對PPARγ進行負向調控進而抑制其基因調控的活性，這樣的負調控主要是由胞外調節激酶（extracellular
Tsai, Yun-Chih, 蔡昀芝
core
PPARγ and Its Role in Cardiovascular Diseases [PDF]
, 2017 Peroxisome proliferator-activated receptor Gamma (PPARγ), a ligand-activated transcription factor, has a role in various cellular functions as well as glucose homeostasis, lipid metabolism, and prevention of oxidative stress.
Manikandan Panchatcharam +2 more
core +1 more source
Pancreatic Atrophy: A Narrative Review and Surgical Interpretation
Annals of Gastroenterological Surgery, EarlyView.Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino +4 more
wiley +1 more source
Expression studies on PPARγ in pancreatic neuroendocrine tumours
, 2010 MDPancreatic NETs occur with an annual incidence of around 5 per 1,000,000 population per year, with survival rates of between 30 – 97% at 5 years depending on the tumour subtype.
Hanson, Matthew Richard
core
Pharmacologically relevant PPARγ ligands.
, 2017 Pharmacologically relevant PPARγ ligands.
Jakob F. Jensen (2246755) +7 more
core +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young +6 more
wiley +1 more source
, 2011 SummaryInsulin resistance, tissue inflammation, and adipose tissue dysfunction are features of obesity and Type 2 diabetes. We generated adipocyte-specific Nuclear Receptor Corepressor (NCoR) knockout (AKO) mice to investigate the function of NCoR in ...
Ai Chen +29 more
core +1 more source