Results 111 to 120 of about 74,506 (264)
Ciglitazone—a human PPARγ agonist—disrupts dorsoventral patterning in zebrafish [PDF]
, 2019 Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation.
Cheng, Vanessa +3 more
core +1 more source
Equine models in translational medicine: A comparative approach to human health
Animal Models and Experimental Medicine, EarlyView.This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.DPSCs, hepatocytes, and exosomes were tested for liver fibrosis therapy. Exosome‐based treatment exhibited superior antioxidative and regenerative effects. Liver enzymes, oxidative stress, and profibrotic markers were significantly reduced. α‐SMA, desmin, and related gene expression were downregulated.
Sahar Rahimi +3 more
wiley +1 more source
PPARγ et homéostasie intestinale
, 2018 PPARγ is a ligand-activated nuclear receptor that controls, in various organs, numerous cellular functions, involved in the control of inflammation, carcinogenesis or metabolism.
Fumery, Mathurin
core
Animal Research and One Health, EarlyView.Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang +10 more
wiley +1 more source
PPARγ gene expression analysis in psoriasis treatment
, 2021 Introduction. PPARγ is the most studied PPAR subtype and is expressed predominantly in adipose tissue, heart, colon, kidney, spleen, intestine, skeletal muscle, liver, macrophages, and skin.
N. N. Potekaev +5 more
core +1 more source
Animal Research and One Health, EarlyView.This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang +9 more
wiley +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2018 Objective: To examine the effect of combination of Andrographis paniculata herb fraction (AHF) and Centella asiatica herb fraction (CHF) on PPARγ and GLUT4 mRNA expressions in 3T3-L1 adipocyte, and its effect on insulin-stimulated glucose uptake. Methods:
LOM. Fitrawan +4 more
doaj +1 more source
Animal Research and One Health, EarlyView.Schematic diagram illustrating how miR‐222 promotes bovine intramuscular adipogenesis by targeting DDIT4 to activate the mTORC1 signaling pathway. ABSTRACT Intramuscular fat (IMF) is a key determinant of beef quality, particularly with respect to tenderness, flavor, and juiciness.
Jianbing Tan +7 more
wiley +1 more source
Characterization of wildtype and sumoylation mutant PPARγ.
, 2015 (A) Luciferase reporter assay of wildtype and sumoylation mutant PPARγ plasmids. RLU, relative luciferase unit. (B) Tetracycline-induced expression of PPARγ and EGFP protein in stably transfected HBEC-C1-wt-PPARγ clone. A microscopic view of tetracycline-
Byung-Il Yeh (780284) +8 more
core +1 more source