Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang +12 more
wiley +1 more source
(p)ppGpp and the bacterial cell cycle
Genes of the Rel/Spo homolog (RSH) superfamily synthesize and/or hydrolyse the modified nucleotides pppGpp/ ppGpp (collectively referred to as (p)ppGpp) and are prevalent across diverse bacteria and in plant chloroplasts. Bacteria accumulate (p)ppGpp in response to nutrient deprivation (generically called the stringent response) and elicit appropriate ...
Aanisa, Nazir, Rajendran, Harinarayanan
openaire +2 more sources
Data_Sheet_1_Dynamic Metabolic Response to (p)ppGpp Accumulation in Pseudomonas putida.PDF
The stringent response is a ubiquitous bacterial reaction triggered by nutrient deprivation and mediated by the intracellular concentrations of ppGpp and pppGpp.
Fabien Létisse (424703) +1 more
core +1 more source
Make and break the alarmone: regulation of (p)ppGpp synthetase/hydrolase enzymes in bacteria
Bacteria use dedicated mechanisms to respond adequately to fluctuating environments and to optimize their chances of survival in harsh conditions. One of the major stress responses used by virtually all bacteria relies on the sharp accumulation of an ...
Séverin Ronneau, Régis Hallez
semanticscholar +1 more source
Transcription of photosynthetic genes in the plant chloroplast: lessons from bacteria
SUMMARY The RNA polymerase that transcribes photosynthetic genes in the plant chloroplast is the largest known transcription enzyme across all domains of life, comprising 21 subunits of bacterial and eukaryotic origin. Recent structural analyses revealed that the core polymerase, inherited from the cyanobacterial ancestor of the chloroplast, is encased
Jessica Moon +5 more
wiley +1 more source
Survival of the Fittest: The Relationship of (p)ppGpp With Bacterial Virulence
The signaling nucleotide (p)ppGpp has been the subject of intense research in the past two decades. Initially discovered as the effector molecule of the stringent response, a bacterial stress response that reprograms cell physiology during amino acid ...
Shivani Kundra +2 more
doaj +1 more source
Stringency in the absence of ppGpp accumulation in Rhodobacter sphaeroides [PDF]
Leucine deprivation of either phototrophically or chemotrophically growing cells of Rhodobacter sphaeroides resulted in a restriction in the continued accumulations of cellular RNA, phospholipids, and protein. Phototrophically growing cells also displayed restrictions in the accumulations of cellular carotenoids and bacteriochlorophyll.
R, Acosta, D R, Lueking
openaire +2 more sources
Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze +3 more
wiley +1 more source
Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nejman, Bożena +4 more
core
Assessment of airway distribution of transnasal solutions in mice by PET/CT imaging. [PDF]
PURPOSE: Transnasal administration is one of the most common routes for allergen challenge in mouse models of airway diseases. Although this technique is widely used, neither the amount of allergen that reaches the lung nor its airway distribution has ...
Zubeldia, José Manuel +27 more
core +1 more source

