Results 101 to 110 of about 4,765 (208)
Data_Sheet_2_Dynamic Metabolic Response to (p)ppGpp Accumulation in Pseudomonas putida.xlsx
, 2022 The stringent response is a ubiquitous bacterial reaction triggered by nutrient deprivation and mediated by the intracellular concentrations of ppGpp and pppGpp.
Fabien Létisse (424703) +1 more
core +1 more source
Basal Levels of (p)ppGpp in
mBio, 2013 The stringent response (SR), mediated by the alarmone (p)ppGpp, is a conserved bacterial adaptation system controlling broad metabolic alterations necessary for survival under adverse conditions.
Anthony O. Gaca +6 more
doaj +1 more source
(p)ppGpp synthetases are required for the pathogenicity of Salmonella Pullorum in chickens.
Microbiology Research, 2021 Salmonella Pullorum is a pathogen specific to birds that can cause Pullorum disease in young chickens and lead to considerable economic losses in the poultry industry. During transmission and infection, S.
Xin Wang +8 more
semanticscholar +1 more source
Angewandte Chemie, Volume 138, Issue 15, 6 April 2026.We synthesized photocaged, clickable and isotope‐labeled “magic spot” Nucleotides and delivered them into Escherichia coli comparing different approaches. Light‐controlled release inside living cells enabled tracking of their conversion from pppGpp to ppGpp by capillary electrophoresis mass spectrometry and revealed their impact on the growth rate of a
Christoph Popp +12 more
wiley +1 more source
Investigation on Bacterial Signaling through Generation of a ppGpp Biosensor
, 2022 Guanosine tetraphosphate (ppGpp) is a bacterial signaling molecule involved in activating the stringent response, a cellular reaction to environmental stress that downregulates cell division and metabolism processes to conserve nutrients.
Robinson, Andrew
core
Acta Biomedica Scientifica, 2022 Signaling molecules such as indole (product of tryptophan catabolism) and (p)ppGpp (stringent response regulator) are involved in regulation of physiological processes in bacterial cells aimed to adapt to antibiotics and stresses.
N. M. Kashevarova +3 more
doaj +1 more source
Controlled Delivery and Light‐Induced Release of Magic Spot Nucleotides in Escherichia coli
Angewandte Chemie International Edition, Volume 65, Issue 15, 6 April 2026.We synthesized photocaged, clickable and isotope‐labeled “magic spot” Nucleotides and delivered them into Escherichia coli comparing different approaches. Light‐controlled release inside living cells enabled tracking of their conversion from pppGpp to ppGpp by capillary electrophoresis mass spectrometry and revealed their impact on the growth rate of a
Christoph Popp +12 more
wiley +1 more source
Frontiers in Microbiology, 2020 Stringent response mediated by modified guanosine nucleotides is conserved across bacteria and is regulated through the Rel/Spo functions. In Escherichia coli, RelA and SpoT proteins synthesize the modified nucleotides ppGpp and pppGpp, together referred
Rajeshree Sanyal +2 more
doaj +1 more source
Forming and waking dormant cells: The ppGpp ribosome dimerization persister model
Biofilm, 2020 Procaryotes starve and face myriad stresses. The bulk population actively resists the stress, but a small population weathers the stress by entering a resting stage known as persistence.
T. Wood, Sooyeon Song
semanticscholar +1 more source
Molecular Informatics, Volume 45, Issue 4, April 2026.A DeepQSAR framework integrating a feed‐forward neural network and a recurrent neural network (RNN) was developed to identify antimicrobial peptides with enhanced antibiofilm and antimicrobial activity. The feed‐forward model was trained on in‐house antibiofilm IC50 data to capture quantitative structure–activity relationships, and its learned features
Jiaying You +5 more
wiley +1 more source