The synthesis and function of the alarmone (p)ppGpp in firmicutes
In most bacteria, nutrient limitations provoke the stringent control by the rapid synthesis of the alarmones pppGpp and ppGpp. The most prominent and highly conserved reaction is the repression of rRNA synthesis. Additionally, (p)ppGpp synthesis is also linked to many other physiological changes involving gene activation/repression but also protein ...
Christiane, Wolz +2 more
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Em defesa dos direitos sociais: A luta pela proteção e pela liberdade em cenários voláteis
A proposta do estudo é discutir sobre as repercussões que incidem sobre os direitos sociais a partir de uma concepção assentada nas relações constituídas entre Estado e sociedade, tomando como ponto de partida o regime democrático brasileiro e as ...
Jairo de Carvalho Guimarães +1 more
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Sustained ppGpp production underpins months-long survival of a bacterium in growth arrest
When growing bacteria start to reach stationary phase, the nucleotide guanosine tetra-phosphate (ppGpp) accumulates intracellularly and regulates the transition of cells from growth to growth arrest.
Elizabeth M. Fones +3 more
doaj +1 more source
Clinical Rel mutations that increase basal (p)ppGpp promote conjugal transfer of staphylococcal resistance plasmids. [PDF]
Deventer AT +7 more
europepmc +1 more source
Suppressor analysis in <i>Synechococcus elongatus</i> PCC7942 reveals key roles of (p)ppGpp in survival and nucleotide homeostasis. [PDF]
Llop A +5 more
europepmc +1 more source
Loss of the plastidial signaling molecule, ppGpp, accumulation alters nuclear gene expression during nitrogen starvation. [PDF]
Nemoto T +7 more
europepmc +1 more source
Short autoinhibitory sequences control phase separation of an essential bacterial transcription termination factor. [PDF]
Krypotou E +6 more
europepmc +1 more source
Mutations in RNA polymerase that drive the emergence of antibiotic resistance. [PDF]
Patel Y, Helmann JD.
europepmc +1 more source

