Results 51 to 60 of about 7,972 (181)
MicrobiologyOpen, Volume 15, Issue 4, August 2026.This paper aims to address critical gaps in the literature by providing a comprehensive, integrative synthesis of recent advances in Streptomyces strain improvement, with a particular focus on optimizing secondary metabolite production through a multidisciplinary approach.
Anum Goraya +5 more
wiley +1 more source
Stringency in the absence of ppGpp accumulation in Rhodobacter sphaeroides [PDF]
Journal of Bacteriology, 1987 Leucine deprivation of either phototrophically or chemotrophically growing cells of Rhodobacter sphaeroides resulted in a restriction in the continued accumulations of cellular RNA, phospholipids, and protein. Phototrophically growing cells also displayed restrictions in the accumulations of cellular carotenoids and bacteriochlorophyll.
R, Acosta, D R, Lueking
openaire +2 more sources
Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf +10 more
wiley +1 more source
Proteomic Analysis of Lactococcus lactis FM03 Under Prolonged Alkaline Stress
Environmental Microbiology, Volume 28, Issue 7, July 2026.Overview of alkaline resistance mechanisms in Lactococcus lactis FM03. Sustained growth at pH 8 triggers extensive physiological remodelling, including activation of general stress response proteins, suppression of acid resistance, elevated amino acid production, altered cell wall biosynthesis, and doubling of the cell wall thickness.
Tamara A. L. Bendig +4 more
wiley +1 more source
Frontiers in Microbiology, 2020 Stringent response mediated by modified guanosine nucleotides is conserved across bacteria and is regulated through the Rel/Spo functions. In Escherichia coli, RelA and SpoT proteins synthesize the modified nucleotides ppGpp and pppGpp, together referred
Rajeshree Sanyal +2 more
doaj +1 more source
Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing
Advanced Science, Volume 13, Issue 33, 15 June 2026.Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu +7 more
wiley +1 more source
Frontiers in Microbiology, 2020 The nucleotide alarmone (p)ppGpp, signaling the stringent response, is known for more than 5 decades. The cellular turnover of the alarmone is regulated by RelA/SpoT homolog (RSH) superfamily of enzymes.
Sushma Krishnan, Dipankar Chatterji
doaj +1 more source
Acta Biomedica Scientifica, 2022 Signaling molecules such as indole (product of tryptophan catabolism) and (p)ppGpp (stringent response regulator) are involved in regulation of physiological processes in bacterial cells aimed to adapt to antibiotics and stresses.
N. M. Kashevarova +3 more
doaj +1 more source
Molecular Microbiology, Volume 125, Issue 6, Page 506-545, June 2026.Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang +12 more
wiley +1 more source
mBio, 2021 During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of a stress signaling network termed the stringent response. RsgA, RbgA, Era, and HflX are four ribosome-associated GTPases (RA-GTPases) that bind to (p)ppGpp in ...
Daniel J. Bennison +5 more
doaj +1 more source