Results 71 to 80 of about 14,528 (201)
Epitranscriptomics as a Candidate Universal Modulator of Dormancy Transitions
Ecology and Evolution, Volume 16, Issue 2, February 2026.Dormancy is presented as a conserved, reversible survival program in which epitranscriptomic RNA modifications are proposed to provide a rapid, energy‐efficient layer that establishes, maintains, and terminates the state by modulating mRNA stability, translation, and localization.
Ehsan Pashay Ahi
wiley +1 more source
Frontiers in Microbiology, 2020 The nucleotide alarmone (p)ppGpp, signaling the stringent response, is known for more than 5 decades. The cellular turnover of the alarmone is regulated by RelA/SpoT homolog (RSH) superfamily of enzymes.
Sushma Krishnan, Dipankar Chatterji
doaj +1 more source
Acta Biomedica Scientifica, 2022 Signaling molecules such as indole (product of tryptophan catabolism) and (p)ppGpp (stringent response regulator) are involved in regulation of physiological processes in bacterial cells aimed to adapt to antibiotics and stresses.
N. M. Kashevarova +3 more
doaj +1 more source
Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]
, 2011 The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nadratowska-Wesołowska, Beata +4 more
core
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah +8 more
wiley +1 more source
Microbial Cell, 2023 The bacterial stringent response and its effector alarmone guanosine penta- or tetra – phosphates (p)ppGpp are vital for bacterial tolerance and survival of various stresses in environments (including antibiotics) and host cells (viru-lence).
Paulina Katarzyna Grucela +4 more
doaj +1 more source
(p)ppGpp and the bacterial cell cycle
Journal of Biosciences, 2016 Genes of the Rel/Spo homolog (RSH) superfamily synthesize and/or hydrolyse the modified nucleotides pppGpp/ ppGpp (collectively referred to as (p)ppGpp) and are prevalent across diverse bacteria and in plant chloroplasts. Bacteria accumulate (p)ppGpp in response to nutrient deprivation (generically called the stringent response) and elicit appropriate ...
Aanisa, Nazir, Rajendran, Harinarayanan
openaire +2 more sources
Understanding the development of bacterial colony: Physiology, new technology, and modeling
Quantitative Biology, Volume 13, Issue 4, December 2025.Abstract Bacterial colonies, as dynamic ecosystems, display intricate behaviors and organizational structures that profoundly influence their survival and functionality. These communities engage in physiological and social interactions, resulting in remarkable spatial heterogeneity.
Jingwen Zhu, Pan Chu, Xiongfei Fu
wiley +1 more source
mBio, 2021 During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of a stress signaling network termed the stringent response. RsgA, RbgA, Era, and HflX are four ribosome-associated GTPases (RA-GTPases) that bind to (p)ppGpp in ...
Daniel J. Bennison +5 more
doaj +1 more source
Engineering Bacteria as Living Therapeutics in Cancer Therapy
Advanced Science, Volume 12, Issue 42, November 13, 2025.Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen +6 more
wiley +1 more source