Results 81 to 90 of about 14,528 (201)
Control of Nucleotide Metabolism and Ribosomal Ribonucleic Acid Synthesis During Nitrogen Starvation of \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
, 1972 Ribosomal ribonucleic acid (RNA) synthesis and ribonucleoside triphosphate metabolism were studied in cultures of Escherichia coli subjected to starvation for inorganic nitrogen.
Irr, Joseph D.
core +1 more source
Protective Action of ppGpp in Microcin J25-Sensitive Strains [PDF]
Journal of Bacteriology, 2008 ABSTRACTAsEscherichia colistrains enter the stationary phase of growth they become more resistant to the peptide antibiotic microcin J25. It is known that starvation for nutrients such as amino acids or glucose leads to increases in guanosine 3′,5′-bispyrophosphate (ppGpp) levels and that the intracellular concentration of this nucleotide increases as ...
Pomares, Maria Fernanda +3 more
openaire +3 more sources
Antibiotic Resistance: A Genetic and Physiological Perspective
MedComm, Volume 6, Issue 11, November 2025.The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy +9 more
wiley +1 more source
mBio, 2020 The initiation of Escherichia coli chromosomal DNA replication starts with the oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The amount of ori DNA per cell directly correlates with the growth rate.
Llorenç Fernández-Coll +6 more
doaj +1 more source
Broad-spectrum anti-biofilm peptide that targets a cellular stress response. [PDF]
PLoS Pathogens, 2014 Bacteria form multicellular communities known as biofilms that cause two thirds of all infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional antibiotics.
César de la Fuente-Núñez +4 more
doaj +1 more source
Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen [PDF]
, 2017 The Bartonella gene transfer agent (BaGTA) is an archetypical example for domestication of a phage-derived element to permit high-frequency genetic exchange in bacterial populations.
Christen, Beat +5 more
core +1 more source
Metabolic Origin, Role and Fate of the Denaturant Guanidine
Microbial Biotechnology, Volume 18, Issue 11, November 2025.The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin +3 more
wiley +1 more source
Conceptual model of E. coli transcriptional machinery [PDF]
, 2011 At the moment one type of analysis of transcription regulatory networks (TRNs) in prokaryotes is topological analysis of graph structure of possible regulatory interaction links (see for example [1]).
Anatoly Sorokin +2 more
core +2 more sources
Bacterial global regulators DksA/ppGpp increase fidelity of transcription [PDF]
Nucleic Acids Research, 2015 Abstract Collisions between paused transcription elongation complexes and replication forks inevitably happen, which may lead to collapse of replication fork and could be detrimental to cells. Bacterial transcription factor DksA and its cofactor alarmone ppGpp were proposed to contribute to prevention of such collisions, although the ...
Roghanian M, Zenkin N, Yuzenkova Y
openaire +3 more sources
mLife, Volume 4, Issue 5, Page 551-566, October 2025.Abstract Indole‐3‐acetic acid (IAA) is an important plant hormone that regulates a variety of physiological processes in plants, and it is also produced by some microbes. However, the biosynthesis and roles of IAA in microorganisms, particularly in plant pathogens, remain to be determined.
Sinan Li +5 more
wiley +1 more source