Identity and functions of inorganic and inositol polyphosphates in plants
New Phytologist, Volume 225, Issue 2, Page 637-652, January 2020., 2020 Summary Inorganic polyphosphates (polyPs) and inositol pyrophosphates (PP‐InsPs) form important stores of inorganic phosphate and can act as energy metabolites and signaling molecules. Here we review our current understanding of polyP and inositol phosphate (InsP) metabolism and physiology in plants.
Laura Lorenzo‐Orts +2 more
wiley +1 more source
The inositol pyrophosphate metabolism of Dictyostelium discoideum does not regulate inorganic polyphosphate (polyP) synthesis [PDF]
, 2021 Initial studies on the inositol phosphates metabolism were enabled by the social amoeba Dictyostelium discoideum. The abundant amount of inositol hexakisphosphate (IP6 also known as Phytic acid) present in the amoeba allowed the discovery of the more ...
Borghi, F +8 more
core
Identification and characterization of evolutionarily conserved inositol pyrophosphate phosphohydrolases in plants [PDF]
, 2023 Inositol phosphates (InsPs), phosphate esters of myo-inositol, are cellular regulators with critical roles in a wide range of cellular processes in eukaryotes.
Gaugler, Philipp
core +1 more source
Genetic analysis of cell cycle and chromatin regulation in quiescent fission yeast cells [PDF]
, 2022 During proliferation, cells produce their genetic materials to increase the number of cells, while in the absence of nutrients or by the induction of stimulus, the proliferative phase is stopped and entry into quiescence is triggered to increase their ...
Zahedi, Yasaman
core +1 more source
The PPIP5K Family Member Asp1 Controls Inorganic Polyphosphate Metabolism in S. pombe [PDF]
, 2021 Inorganic polyphosphate (polyP) which is ubiquitously present in both prokaryotic and eukaryotic cells, consists of up to hundreds of orthophosphate residues linked by phosphoanhydride bonds.
Fleig, U +3 more
core
INOSITOL (1,3,4) TRIPHOSPHATE 5/6 KINASE1-Dependent Inositol Polyphosphates Regulate Auxin Responses in Arabidopsis [PDF]
, 2022 The combinatorial phosphorylation of myo-inositol results in the generation of different inositol phosphates (InsPs), of which phytic acid (InsP6) is the most abundant species in eukaryotes.
Bhattacharjee, Saikat +18 more
core +1 more source
bioRxivInositol pyrophosphates (PP-InsPs) are nutrient messengers whose cellular concentration must be tightly regulated. Diphosphoinositol pentakisphosphate kinases (PPIP5Ks) generate the active signaling molecule 1,5-InsP8.
Laurent F +10 more
europepmc +2 more sources
Use of Protein Kinase-Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors. [PDF]
SLAS Discov, 2018 Inositol hexakisphosphate kinases (IP6Ks) regulate a myriad of cellular processes, not only through their catalytic activity (which synthesizes InsP7, a multifunctional inositol pyrophosphate signaling molecule) but also through protein–protein ...
Puhl-Rubio AC +11 more
europepmc +2 more sources
Cellular Functions of myo-Inositol-Derived Signaling Molecules in Yeast and Plants during Abiotic and Biotic Stresses [PDF]
, 2021 Myo-Inositol (Ins)-derived molecules are involved in many cellular processes. Besides the role as compatible solute, Ins represents the building block for a variety of molecules, which function as signaling molecules. Cells utilize insoluble (lipid-bound)
Johnen, Philipp
core +1 more source
Arabidopsis inositol phosphate kinases, IPK1 and ITPK1, constitute a metabolic pathway in maintaining phosphate homeostasis [PDF]
, 2018 Emerging studies have implicated a close link between inositol phosphate (InsP) metabolism and cellular phosphate (Pi) homeostasis in eukaryotes; however, whether a common InsP species is deployed as an evolutionarily conserved metabolic messenger to ...
Alcazar-Roman +104 more
core +2 more sources