Results 141 to 150 of about 1,051,280 (287)

Reply to: Deprescribing after DBS in Dystonia: Promise, Pitfalls, and a Path Forward

Movement Disorders Clinical Practice, EarlyView.
Marcela A. Montiel, Alfonso Fasano
wiley   +1 more source

Clinical and Imaging Characteristics of Parkinson's Disease with Negative Alpha‐Synuclein Seed Amplification Assay

Movement Disorders, EarlyView.
Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker, Jacopo Pasquini, Seung Ho Choi, David‐Erick Lafontant, Seyed‐Mohammad Fereshtehnejad, Yashar Zeighami, Piergiorgio Grillo, Giulietta M. Riboldi, Houman Azizi, Roqaie Moqadam, Un Jung Kang, Kelly N.H. Nudelman, Andrew Siderowf, Caroline M. Tanner, Thomas F. Tropea, Tatiana Foroud, Lana M. Chahine, Brit Mollenhauer, Kalpana M. Merchant, Douglas Galasko, Christopher S. Coffey, Roseanne D. Dobkin, Ethan G. Brown, Roy N. Alcalay, Daniel Weintraub, Kenneth Marek, Tanya Simuni, Paulina Gonzalez‐Latapi, Nicola Pavese, Kathleen L. Poston, the Parkinson's Progression Markers Initiative   +30 more
wiley   +1 more source

Safe Sport in Mediterranean Contexts: Cultural Logics of Harm, Silence, and Authority. [PDF]

Eur J Sport Sci
Chroni SA, Skille EÅ, Hansen PØ, Alexopoulos A, de Dios Benítez-Sillero J, Brazier R, Calmaestra J, Kavoura A, Kerr-Cumbo R, Lara-Bercial S, Navarro A, Nery M, Nicolini C, Verhelle H, Vivirito S, Hassandra M.   +15 more
europepmc   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

Movement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar, Pinky Agarwal, Karen Anderson, Daniel Claassen, Marissa Dean, Andrew Duker, Burton Scott, Benjamin Hoehn, Ann Mongan, Ping Lin, Ellen Cahir‐McFarland, Lori Taylor, Glenn Morrison, Ted Yednock, Sanjay Keswani, Henk‐Andre Kroon   +15 more
wiley   +1 more source

Long-term immune recovery under continuous antiretroviral therapy (ART) among ART-naive people living with HIV in two cohorts in Germany. [PDF]

Infection
Koppe U, Pörtner K, Kollan C, Pantke A, Sailer A, Dehmel K, Esser S, Jensen BO, Rockstroh JK, Schäfer G, Schürmann D, Stoll M, Wasmuth JC, Kurth T, Gunsenheimer-Bartmeyer B, HIV-1 Seroconverter Cohort and the ClinSurv-HIV Cohort.   +15 more
europepmc   +1 more source

Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation

Movement Disorders, EarlyView.
Abstract Adaptive deep brain stimulation (aDBS) represents an important evolution in the treatment of Parkinson's disease (PD), building on conventional DBS (cDBS) by adjusting stimulation in response to real‐time physiological signals. By enabling dynamic targeting of disease‐related neural activity, aDBS offers the potential for more precise ...
Thomas Koeglsperger, Maximilian Scherer, Andrea A. Kühn, Alexandre Eusebio, Alfonso Fasano, Joachim K. Krauss   +5 more
wiley   +1 more source

[Assisted suicide in Germany-initial analysis of data from a reporting platform and potential implications for the development of a guideline]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Schildmann J, Pollmächer T, Simon A, Sommerlatte S, Marckmann G.   +4 more
europepmc   +1 more source

Reply to: Severity‐Based and Family‐Centered Approaches to Deep Brain Stimulation in GNAO1‐Related Disorders

Movement Disorders Clinical Practice, EarlyView.
Marcela A. Montiel, Carolina Gorodetsky, Nardo Nardocci, Alfonso Fasano   +3 more
wiley   +1 more source

Practice as research as a decolonial praxis: Yoruba culture retrieval. [PDF]

Front Sociol
Rose L.
europepmc   +1 more source

Neurodevelopmental Disorder with Dystonia and Chorea Linked to De Novo Variants in the Splicing Regulator SRRM4

Movement Disorders, EarlyView.
Abstract Background SRRM4 is an exclusively neural‐expressed splicing‐factor gene not yet associated with a monogenic condition. Objective We sought to delineate movement disorders caused by SRRM4 variants. De novo splice‐donor‐site variants at position +2 of intron 5 of SRRM4 (c.464+2T>C, c.464+2T>A) occurred in three unrelated patients with dystonia ...
Philip Harrer, Volker Kittke, Alice Saparov, Alexej Knaus, Shimriet Zeidler, Rachel Schot, Florian Kraft, Matthias Begemann, Suzanna Koudijs, Ugo Sorrentino, Chen Zhao, Ivana Dzinovic, Martin Pavlov, Elisabeth Graf, Antonia M. Stehr, Peter M. Krawitz, Christian Wilhelm, Saskia Biskup, Fahd Alsalloum, Steffen Berweck, Juliane Winkelmann, Konrad Oexle, Ingo Kurth, G. Christoph Korenke, Michael Zech   +24 more
wiley   +1 more source