Results 11 to 20 of about 22,455 (256)

Prazosin for the management of behavioural and psychological symptoms of dementia

Drugs in Context, 2022
Prazosin, a centrally acting α1 adrenoceptor antagonist, has been included in two published algorithms amongst the list of medications that may be used in the management of behavioural and psychological symptoms of dementia (BPSD).
Rajesh R Tampi, Deena J Tampi, Syeda Arshiya Farheen, Mahwish Adnan, Dhweeja Dasarathy   +4 more
doaj   +1 more source

Muting Bacterial Communication: Evaluation of Prazosin Anti-Quorum Sensing Activities against Gram-Negative Bacteria Pseudomonas aeruginosa, Proteus mirabilis, and Serratia marcescens

Biology, 2022
Quorum sensing (QS) controls the production of several bacterial virulence factors. There is accumulative evidence to support that targeting QS can ensure a significant diminishing of bacterial virulence.
Abrar K. Thabit, Khalid Eljaaly, Ayat Zawawi, Tarek S. Ibrahim, Ahmed G. Eissa, Samar S. Elbaramawi, Wael A. H. Hegazy, Mahmoud A. Elfaky   +7 more
doaj   +1 more source

Influence of prazosin on systemic iron levels and the associated iron metabolic alterations in spontaneously hypertensive rats

Pharmacology Research & Perspectives, 2022
The relationship between cardiovascular diseases and iron disorders has gained increasing attention; however, the effects of hypotensive drugs on iron metabolic alterations in hypertension are not well understood.
Hengrui Chang, Dong Zhang, Zhen Xin, Pengfei Zhang, Wenyuan Ding, Yan‐Zhong Chang   +5 more
doaj   +1 more source

Effects of chronic prazosin, an alpha-1 adrenergic antagonist, on anxiety-like behavior and cortisol levels in a chronic unpredictable stress model in zebrafish (Danio rerio) [PDF]

PeerJ, 2020
Post-traumatic stress disorder (PTSD) is often associated with significant neuroendocrine dysfunction and a variety of other symptoms. Today, there are limited efficacious treatment options for PTSD, none of which directly target the dysfunction observed
Michael P. O’Daniel, Maureen L. Petrunich-Rutherford   +1 more
doaj   +2 more sources

The efficacy of administration of prazosin in reducing the risk of recurrent urethral obstruction in male cats

Veterinary Evidence, 2023
PICO Question In male cats presenting with urethral obstruction, does administration of prazosin compared with no administration of prazosin reduce the incidence of recurrent urethral obstruction within the first month of initial presentation ...
Rebecca Hearne
doaj   +1 more source

Controlling of Bacterial Virulence: Evaluation of Anti-Virulence Activities of Prazosin against Salmonella enterica

Antibiotics, 2022
Salmonella enterica is a Gram-negative orofecal transmitted pathogen that causes a wide diversity of local and systemic illnesses. Salmonella enterica utilizes several interplayed systems to regulate its invasion and pathogenesis: namely, quorum sensing (
Mahmoud A. Elfaky, Abrar K. Thabit, Khalid Eljaaly, Ayat Zawawi, Ahmed S. Abdelkhalek, Ahmad J. Almalki, Tarek S. Ibrahim, Wael A. H. Hegazy   +7 more
doaj   +1 more source

The "Ram Effect": A "Non-Classical" Mechanism for Inducing LH Surges in Sheep [PDF]

, 2016
During spring sheep do not normally ovulate but exposure to a ram can induce ovulation. In some ewes an LH surge is induced immediately after exposure to a ram thus raising questions about the control of this precocious LH surge.
A Caraty, A Caraty, A Chanvallon, A Chanvallon, AC Gore, AE Herbison, AL Goodman, AM Etgen, Audrey Chanvallon, C Fabre-Nys, C Fabre-Nys, C Fabre-Nys, C Fabre-Nys, CA Barraclough, CE Adams, CE Adams, CH Conaway, CH Wu, CJ Scott, Claude Fabre-Nys, CM Oldham, CS Corker, DE Wildt, DE Wright, DF Hardy, Didier Lomet, DR Lindsay, DT Baird, DT Pearce, E Elias, FJ Karsch, FJ Karsch, GB Martin, GW Montgomery, H Gelez, HG Spies, IJ Clarke, J Bakker, JA Banks, JA Rawson, Joëlle Dupont, JP Signoret, JP Signoret, JP Signoret, JR Day, K Brown-Grant, K Maeda, L Dufy-Barbe, L Xia, Lionel Lardic, M Acosta-Martinez, MJ Baum, MJ Gibson, MS Smith, MX Zarrow, NP Evans, OR Dyrmundsson, P Mauleon, P Richard, Peter J. Hansen, Q Li, R Papay, R Ungerfeld, RD Randel, RE Szawka, Rex J. Scaramuzzi, RJ Scaramuzzi, RL Goodman, RL Goodman, RL Goodman, RL Goodman, RL Hauger, S Ben Saïd, S Yamada, SM Moenter, SP Yang, SP Yang, SP Yang, SR Milligan, SR Milligan, SR Wersinger, Stéphanie Martinet, VD Ramirez, W Jöchle, Y Tillet, Y Tillet   +85 more
core   +9 more sources

A comparative study of using scorpion antivenom versus scorpion antivenom and prazosin drug for scorpion stings management in Sohag University Hospitals. [PDF]

BMC Pharmacol Toxicol
Shokry Zaghary MM, Abd ElKader MM.
europepmc   +3 more sources

A Pilot retrospective analysis of alpha-blockers on recurrence in men with localised prostate cancer treated with radiotherapy [PDF]

, 2020
While alpha-blockers are commonly used to reduce lower urinary tract symptoms in prostate cancer patients receiving radiotherapy, their impact on response to radiotherapy remains unknown.
Anoopkumar-Dukie, Shailendra, Chess-Williams, Russ, Christie, David, Hart, Jordan, McDermott, Catherine, Sellers, Donna J, Spencer, Briohny   +6 more
core   +1 more source

Investigation of the Atypical Glass Transition and Recrystallization Behavior of Amorphous Prazosin Salts

Pharmaceutics, 2011
This manuscript studied the effect of counterion on the glass transition and recrystallization behavior of amorphous salts of prazosin. Three amorphous salts of prazosin, namely, prazosin hydrochloride, prazosin mesylate and prazosin tosylate were ...
Arvind K. Bansal, Dharmesh Popat, Lokesh Kumar   +2 more
doaj   +1 more source