Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma +3 more
core +1 more source
An update on epidemiology and management practices of Scorpion envenomation in India
Introduction: Scorpion envenomation is a life-threatening condition, particularly for children. Therefore, it is essential for primary care health providers to suspect, identify, and manage this condition early to prevent death and minimize morbidity ...
Rakesh Kumar
doaj +1 more source
Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G +6 more
core +2 more sources
Effectiveness of Sensitisation Programme on Prazosin Therapy for Scorpion Envenomation at Primary and Secondary Healthcare Level [PDF]
Introduction: Scorpion envenomation is a life-threatening paediatric emergency. Prazosin-an alpha-1 blocker is the gold standard therapy for scorpion envenomation. Many children with scorpion envenomation were under-treated at Primary Healthcare (PHC)
B RAMESHBABU +4 more
doaj +1 more source
Avenanthramide C From Oats Possibly Exerts Anti-Inflammatory Effects in Human Umbilical Vein Endothelial Cells. [PDF]
ABSTRACT Chronic kidney disease (CKD) is associated with inflammation and cardiovascular complications and is partly exacerbated by the uremic toxin indoxyl sulfate (IS). IS is known to activate the aryl hydrocarbon receptor (AhR) to promote vascular inflammation.
Sasaki H +8 more
europepmc +2 more sources
Hypertension impairs the function of the kidney and its vasculature. Adrenergic activation is involved in these processes by promoting oxidative stress and mitochondrial dysfunction.
Cristian Adrián Márquez-Ramírez +7 more
doaj +1 more source
Management of hypertension at the community level in Sub-Saharan Africa (SSA): towards a rational use of available resources [PDF]
Hypertension is emerging in many developing nations as a leading cause of cardiovascular mortality, morbidity and disability in adults. In sub-Saharan African (SSA) countries it has specificities such as occurring in young and active adults, resulting in
Twagirumukiza, Marc, Van Bortel, Lucas
core +2 more sources
Nitrates for the Management of Acute Heart Failure Syndromes, A Systematic Review [PDF]
© The Author(s) 2016Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS) yet with lack of robust evidence to support their use.
Farag, Mohamed +2 more
core +2 more sources
Pediatric scorpionism in southwest Turkey: the experience of a training and research hospital
Aim: The aim of this study was to evaluate the clinical and laboratory features and prognosis of scorpion stings in children.Methods: This was a retrospective study of children with scorpion stings, who were admitted to the pediatric emergency department
Ayça Esra Akkaya Kuybulu +1 more
doaj +1 more source
Catecholamine-Based Treatment in AD Patients: Expectations and Delusions. [PDF]
In Alzheimer disease, the gap between excellence of diagnostics and efficacy of therapy is wide. Despite sophisticated imaging and biochemical markers, the efficacy of available therapeutic options is limited.
Alessandro eStefani +9 more
core +3 more sources

