Results 131 to 140 of about 27,504 (316)

Prebiotic Investigations and Reaction Network Analysis on the Wöhler‐RNA System

ChemSystemsChem, EarlyView.
The prebiotic reaction toward the Wöhler‐RNA, a Proto‐RNA‐candidate, using aldehydes and biuret or triuret results in a mixture of the α‐ and β‐ furanosides and pyranosides. Investigation of the interconversion of these isomers shows different reactivity and stability of the biuret and triuret analogues as well as between the corresponding furanosides ...
Nathalie J. Kurrle, Maximilian Bechtel, Nathalie Hampel, Oliver Trapp   +3 more
wiley   +1 more source

Oligoglyceric acid synthesis by autocondensation of glyceroyl thioester [PDF]

The autocondensation of the glyceroyl thioester, S-glyceroyl-ethane-thiol, yielded olioglyceric acid. The rates of autocondensation and hydrolysis of the thioester increased from pH 6.5 to pH 7.5 in 2,6-lutidine and imidazole buffers.
Weber, A. L.
core   +1 more source

Complementary Predictors for Asthma Attack Prediction in Children: Salivary Microbiome, Serum Inflammatory Mediators, and Past Attack History

Allergy, EarlyView.
In this two‐phase study, school‐aged children were classified as at risk or no‐risk based on severe attacks during one‐year follow‐up. Four types of prediction models were developed. Salivary bacteria and serum inflammatory markers, while informative alone, complement past asthma attacks in predicting future attack risk.
Shahriyar Shahbazi Khamas, Paul Brinkman, Anne H. Neerincx, Susanne J. H. Vijverberg, Simone Hashimoto, Jelle M. Blankestijn, Jan Willem Duitman, Tamara Dekker, Barbara S. Smids, Suzanne W. J. Terheggen‐Lagro, René Lutter, Nariman K. A. Metwally, Fleur Sondaal, Eric G. Haarman, Peter J. Sterk, Ian M. Adcock, Charles Auffray, Corinna Bang, Aruna T. Bansal, Heike Buntrock‐Döpke, Klaus Bønnelykke, Andrew Bush, Bo Lund Chawes, Kian Fan Chung, Paula Corcuera‐Elosegui, Sven‐Erik Dahlén, Ratko Djukanovic, Louise J. Fleming, Stephen J. Fowler, Andre Franke, Urs Frey, Mario Gorenjak, Susanne Brandstetter, Susanne Harner, Gunilla Hedlin, Michael Kabesch, Nazanin Zounemat‐Kermani, Parastoo Kheirolldein, Alexander Kiefer, Jon R. Konradsen, Aletta D. Kraneveld, Leyre López‐Fernández, Clare S. Murray, Björn Nordlund, Maria Pino‐Yanes, Uroš Potočnik, Graham Roberts, Jakob Stokholm, Søren Johannes Sørensen, Olaia Sardón‐Prado, Dominick E. Shaw, Florian Singer, Ana R. Sousa, Jonathan Thorsen, Antoaneta A. Toncheva, Nadja H. Vissing, Christine Wolff, Mahmoud I. Abdel‐Aziz, Anke H. Maitland‐van der Zee, on behalf of the SysPharmPediA and U‐BIOPRED Consortia   +59 more
wiley   +1 more source

Rewarming the Primordial Soup: Revisitations and Rediscoveries in Prebiotic Chemistry [PDF]

, 2017
Raffaele Saladino, Judit E. Šponer, Jiřı́ Šponer, Ernesto Di Mauro, Jiří Šponer, Ernesto Di Mauro   +5 more
openalex   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Prebiotic chemistry: a review of nucleoside phosphorylation and polymerization. [PDF]

Open Biol, 2023
Guo X, Fu S, Ying J, Zhao Y.
europepmc   +1 more source

Role of the Interchangeable Cations on the Sorption of Fumaric and Succinic Acids on Montmorillonite and its Relevance in Prebiotic Chemistry

, 2021
A. L. Meléndez-López, Marìa Colín-García, Fernando Ortega‐Gutiérrez, J. Cruz-Castañeda   +3 more
openalex   +1 more source

Titan Mare Explorer (TiME): first in situ exploration of an extraterrestrial sea [PDF]

, 2010
The lakes and seas of Titan are a sink of products of photolysis in the atmosphere, and a crucial component in Titan's active methane cycle.
Aharonson, O., Bierhaus, E., Clark, B., Griffith, C., Harri, A.-M., Kantsiper, B., Karkoschka, E., Kirk, R., Lorenz, R. D., Lunine, J. I., Mahaffy, P., Newman, C., Ravine, M., Stofan, E. R., Trainer, M., Waite, H, Zarnecki, J.   +16 more
core  

Prebiotic Chemistry in Nanoconfinement

, 2016
Water presents extremely different properties depending not only on conditions like temperature and pressure but also on the local environment (bulk vs. interfacial water), which in turn profoundly affects chemical reactions in solution. Here, we present the results of extensive ab initio molecular dynamics and metadynamics simulations in which we ...
Munoz-Santiburcio, D., Marx, D.
openaire   +1 more source

E. coli and gut health—For the loser now will be later to win

The FEBS Journal, EarlyView.
In humans, commensal gut bacteria participate in a miniature nitrogen cycle, metabolizing dietary nitrate and nitrite. While these processes can generate harmful N‐nitrosamines, they may also produce beneficial nitric oxide (NO) or ammonium. Hager and colleagues demonstrate that E.
Jon O. Lundberg
wiley   +1 more source