Results 61 to 70 of about 31,847 (287)
Open questions in understanding life’s origins
Communications Chemistry, 2021 The chemical space of prebiotic chemistry is extremely large, while extant biochemistry uses only a few thousand interconnected molecules. Here we discuss how the connection between these two regimes can be investigated, and explore major outstanding ...
Christopher J. Butch +3 more
doaj +1 more source
Sulfidic Anion Concentrations on Early Earth for Surficial Origins-of-Life Chemistry [PDF]
, 2018 A key challenge in origin-of-life studies is understanding the environmental conditions on early Earth under which abiogenesis occurred. While some constraints do exist (e.g., zircon evidence for surface liquid water), relatively few constraints exist on the abundances of trace chemical species, which are relevant to assessing the plausibility and ...
arxiv +1 more source
The first peptides: the evolutionary transition between prebiotic amino acids and early proteins [PDF]
, 2009 The issues we attempt to tackle here are what the first peptides did look like when they emerged on the primitive earth, and what simple catalytic activities they fulfilled.
Buhrman, Harry +4 more
core +5 more sources
Pressure‐Driven Reactivity in Dense Methane‐Nitrogen Mixtures
Angewandte Chemie, EarlyView.CH4 and N2 are abundant molecules in our solar system and are the primary constituents of Titan's atmosphere. Under extreme pressures and temperatures within a diamond anvil cell, CH4 and N2 are demonstrated to react to form a range of compounds, dependent on the conditions and initial concentrations.
Hannah A. Shuttleworth +13 more
wiley +2 more sources
Life, 2021 Template-free nonenzymatic polymerization of 3′,5′ cyclic nucleotides is an emerging topic of the origin of life research. In the last ten years, a number of papers have been published addressing various aspects of this process.
Judit E. Šponer +6 more
doaj +1 more source
Organic chemistry in a CO2 rich early Earth atmosphere [PDF]
Earth and Planetary Science Letters, Elsevier, 2017, 479, pp.34-42, 2018 The emergence of life on the Earth has required a prior organic chemistry leading to the formation of prebiotic molecules. The origin and the evolution of the organic matter on the early Earth is not yet firmly understood. Several hypothesis, possibly complementary, are considered. They can be divided in two categories: endogenous and exogenous sources.
arxiv +1 more source
Twenty years of "Lipid World": a fertile partnership with David Deamer [PDF]
, 2019 "The Lipid World" was published in 2001, stemming from a highly effective collaboration with David Deamer during a sabbatical year 20 years ago at the Weizmann Institute of Science in Israel.
Kahana, Amit +2 more
core +1 more source
A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation
Angewandte Chemie, EarlyView.The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu +9 more
wiley +2 more sources
Molecular Precursors of the RNA-World in Space: New Nitriles in the G+0.693−0.027 Molecular Cloud
Frontiers in Astronomy and Space Sciences, 2022 Nitriles play a key role as molecular precursors in prebiotic experiments based on the RNA-world scenario for the origin of life. These chemical compounds could have been partially delivered to the young Earth from extraterrestrial objects, stressing the
Víctor M. Rivilla +15 more
doaj +1 more source
Heat‐Flow‐Driven Nonequilibria for Prebiotic Chemistry [PDF]
The origin of life, being one of the most fascinating questions in science, is increasingly addressed by interdisciplinary research. In addition to developing plausible chemical models for synthesizing the first biomolecules from prebiotic building ...
Mast, Christof B.
core +1 more source