Results 231 to 240 of about 303,204 (352)

Pharmacotherapy for Cannabis Use Disorder: Preclinical and Clinical Models. [PDF]

Curr Top Behav Neurosci
Bedillion MF, Moore CF, Weerts EM, Arout CA, Harris HM, Haney M.   +5 more
europepmc   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

Iteration of Tumor Organoids in Drug Development: Simplification and Integration. [PDF]

Pharmaceuticals (Basel)
Zhao R, Feng Q, Xia Y, Liao L, Xie S.
europepmc   +1 more source

Table 1 from Preclinical Evaluation of STI-8811, a Novel Antibody–Drug Conjugate Targeting BCMA for the Treatment of Multiple Myeloma

Aaron D. Springer, Rengang Wang, Jiawei Wang, Qinyi Du, Willie Pi, Austin Q. Nguyen, Xiaoqing Li, Alisher Khasanov, Tong Zhu, Zheng Yan, Yufeng Hong, Heyue Zhou, Yanliang Zhang, Lisa Kerwin, Lingna Li, Henry Ji, Hong Zhang   +16 more
openalex   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Medicinal Plants and Phytochemicals in Cardioprotection-Mechanistic Pathways and Translational Roadmap. [PDF]

Life (Basel)
Morariu-Briciu DM, Jîjie AR, Bolintineanu SL, Pah AM, Chiriac SD, Chevereșan A, Dumitrașcu V, Prodan Bărbulescu C, Jipa R.   +8 more
europepmc   +1 more source

Pharmacokinetic-Pharmacodynamic Evaluations and Experimental Design Recommendations for Preclinical Studies of Anti-tuberculosis Drugs

, 2017
Chunli Chen
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

The FDA's plan to phase out animal testing. [PDF]

Trends Biotechnol
Gerke S, Balamut J, Wagner JK.
europepmc   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source