Results 231 to 240 of about 1,044,728 (382)

Use of Preclinical Drug Vs. Food Choice Procedures to Evaluate Candidate Medications for Cocaine Addiction

Current Treatment Options in Psychiatry, 2015
M. Banks, Blake A. Hutsell, Kathryn L Schwienteck, S. Negus   +3 more
semanticscholar   +1 more source

Free‐Form Microfluidic Microneedle Array Patches

Advanced Functional Materials, EarlyView.
Microfluidic microneedle array patches (MAPs) integrate hollow microneedles with embedded microfluidic channels, fabricated using high‐resolution 3D printing, to enable controlled transdermal delivery of liquid, mixed, or reconstituted therapeutics.
Ian A. Coates, Madison M. Driskill, Netra U. Rajesh, Gabriel Lipkowitz, Dan Ilyn, Yue Xu, Maria T. Dulay, Gunilla B. Jacobson, John R. Tumbleston, Jillian L. Perry, Shaomin Tian, Joseph M. DeSimone   +11 more
wiley   +1 more source

The Use of Nonhuman Primate Models for Advancing HIV PrEP. [PDF]

Viruses
Bekerman E, Callebaut C.
europepmc   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

⁶⁸Ga-NK224 PET/CT Enables Noninvasive Assessment of PD-L1 Expression and Tumor Heterogeneity. [PDF]

Radiol Imaging Cancer
Callow BW, Luker GD.
europepmc   +1 more source

Click chemistry enables preclinical evaluation of targeted epigenetic therapies

Science, 2017
Dean S. Tyler, J. Vappiani, T. Cañeque, E. Lam, A. Ward, O. Gilan, Yih-Chih Chan, Antje Hienzsch, A. Rutkowska, Thilo Werner, Anne J. Wagner, D. Lugo, Richard Gregory, Cesar Ramirez Molina, Neil Garton, Christopher R. Wellaway, Susan Jackson, Laura MacPherson, Margarida Figueiredo, Sabine Stolzenburg, Charles C. Bell, C. House, S. Dawson, E. Hawkins, G. Drewes, R. Prinjha, R. Rodriguez, P. Grandi, M. Dawson   +28 more
semanticscholar   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

De-risking seizure liability: integrating adverse outcome pathways (AOPs), new approach methodologies (NAMs), and in silico approaches while highlighting knowledge gaps. [PDF]

Toxicol Sci
Behl M, Karmaus A, Rao M, Lane T, Harris J, Sachs C, Borrel A, Oyetade O, Unnikrishnan A, Hamm J, Hogberg HT.   +10 more
europepmc   +1 more source

Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins

Advanced Healthcare Materials, EarlyView.
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer, Amelia Hasenauer, Dominic Rütsche, Hao Liu, Jakub Janiak, Michael Nguyen, Karen L. Christman, Marcy Zenobi‐Wong, Parth Chansoria   +8 more
wiley   +1 more source