Results 11 to 20 of about 55,685 (249)

Spatial resolution of a preclinical PET tomograph

Brazilian Journal of Radiation Sciences, 2021
Positron emission tomography (PET) is an important molecular image modality and its application on preclinical research has increased during last decades.
Guilherme Cavalcante de Albuquerque Souza, Rodrigo Modesto Gadelha Gontijo, Juliana Batista da Silva, Marcelo Mamede, Andréa Vidal Ferreira   +4 more
doaj   +3 more sources

Advances in Preclinical PET. [PDF]

Semin Nucl Med, 2022
The classical intent of PET imaging is to obtain the most accurate estimate of the amount of positron-emitting radiotracer in the smallest possible volume element located anywhere in the imaging subject at any time using the least amount of radioactivity.
Adler SS, Seidel J, Choyke PL.
europepmc   +3 more sources

Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation

EJNMMI Research, 2022
Highlights In a focal rat DTH-EAE model of neuroinflammation, dimethyl fumarate decreases the uptake of TSPO PET tracer [18F]GE-180 in the short term. Long-term [18F]GE-180 follow-up did not indicate a treatment effect.
S. K. Vainio, A. M. Dickens, M. Matilainen, F. R. López-Picón, R. Aarnio, O. Eskola, O. Solin, D. C. Anthony, J. O. Rinne, L. Airas, M. Haaparanta-Solin   +10 more
doaj   +1 more source

[18F]Fluoride uptake in various bone types and soft tissues in rat

EJNMMI Research, 2023
Background In the development of new 18F-labelled tracers, it is important to assess the amount of released [18F]fluoride taken up in the bones of experimental animals because all 18F-labelled PET-tracers are prone, to lesser or higher degree, to undergo
Nina Savisto, Tove J. Grönroos, Vesa Oikonen, Johan Rajander, Eliisa Löyttyniemi, Jörgen Bergman, Sarita Forsback, Olof Solin, Merja Haaparanta-Solin   +8 more
doaj   +1 more source

Performance based on NEMA NU-4 2008 Standard of CDTN/CNEN’s Small Animal PET Scanner

Brazilian Journal of Radiation Sciences, 2022
This study aimed to evaluate the general performance of the preclinical PET scanner (LabPET Solo 4, GE) at CDTN/CNEN using the NEMA NU 4-2008 protocol.
Rodrigo Modesto Gadelha Gontijo, Andréa Vidal Ferreira, Juliana Batista da Silva, Marcelo Mamede   +3 more
doaj   +1 more source

Efficiency of 124I radioisotope production from natural and enriched tellurium dioxide using 124Te(p,xn)124I reaction

EJNMMI Physics, 2022
Background 124I Iodine (T $$_{1/2}$$ 1 / 2 = 4.18 d) is the only long-life positron emitter radioisotope of iodine that may be used for both imaging and therapy as well as for 131I dosimetry.
Paweł Bzowski, Damian Borys, Kamil Gorczewski, Agnieszka Chmura, Kinga Daszewska, Izabela Gorczewska, Anna Kastelik-Hryniewiecka, Marcin Szydło, Andrea d’Amico, Maria Sokół   +9 more
doaj   +1 more source

Comparative analysis of image quality parameters and spatial resolution of three Small Animal PET scanner in Brazil

Brazilian Journal of Radiation Sciences, 2023
This study evaluated Image Quality (IQ) parameters and spatial resolution (SR) of Triumph® LabPET systems installed in three different Brazilian preclinical molecular imaging centers.
Rodrigo Modesto Gadelha Gontijo, Andréa Vidal Ferreira, Daniele Faria, Carlos Alberto Buchpiguel, Samuel Greggio, Gianina Venturin, Jader Costa, Juliana Silva, Marcelo Mamede   +8 more
doaj   +1 more source

Proposal of Brazilian National Program for Quality Control in the small animal PET scanners

Brazilian Journal of Radiation Sciences, 2022
In Brazil, currently there are six preclinical molecular imaging centers and seven different small animal PET systems in use. However, there is still no national specific legislation for research laboratories focused on preclinical molecular images ...
Rodrigo Modesto Gadelha Gontijo
doaj   +1 more source

Preclinical and Translational PET/MR Imaging [PDF]

Journal of Nuclear Medicine, 2014
Combined PET and MR imaging (PET/MR imaging) has progressed tremendously in recent years. The focus of current research has shifted from technologic challenges to the application of this new multimodal imaging technology in the areas of oncology, cardiology, neurology, and infectious diseases.
H. F. Wehrl, S. Wiehr, M. R. Divine, S. Gatidis, G. T. Gullberg, F. C. Maier, A.-M. Rolle, J. Schwenck, W. M. Thaiss, B. J. Pichler   +9 more
openaire   +2 more sources

ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein

Translational Neurodegeneration, 2022
Background Hijacking the transferrin receptor (TfR) is an effective strategy to transport amyloid-beta (Aβ) immuno-positron emission tomography (immunoPET) ligands across the blood–brain barrier (BBB).
Gillian Bonvicini, Stina Syvänen, Ken G. Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin   +5 more
doaj   +1 more source