Results 21 to 30 of about 518,230 (247)

Standardisation of preclinical PET/CT protocols across multiple research centres [PDF]

, 2020
Preclinical Positron Emission Tomography/Computed Tomography (PET/CT) is a well-established non-invasive imaging tool for studying disease development/progression, the development of novel radiotracers and pharmaceuticals for clinical applications ...
McDougald, Wendy Anne
core   +1 more source

PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging

Frontiers in Neuroscience, 2022
The development of novel PET imaging agents for synaptic vesicle glycoprotein 2A (SV2A) allowed for the in vivo detection of synaptic density changes, which are correlated with the progression and severity of a variety of neuropsychiatric diseases. While
Takuya Toyonaga, Arman Fesharaki-Zadeh, Arman Fesharaki-Zadeh, Stephen M. Strittmatter, Stephen M. Strittmatter, Richard E. Carson, Zhengxin Cai   +6 more
doaj   +1 more source

Construction and Evaluation of Quantitative Small-Animal PET Probabilistic Atlases for [18F]FDG and [18F]FECT Functional Mapping of the Mouse Brain [PDF]

, 2013
Automated voxel-based or pre-defined volume-of-interest (VOI) analysis of small-animal PET data in mice is necessary for optimal information usage as the number of available resolution elements is limited. We have mapped metabolic ([18F]FDG) and dopamine
Kathleen Vunckx (419666), Michel Koole (419670), Koole, Michel, Aelvoet, Sarah-Ann, Kathleen Vunckx, Cindy Casteels (419665), Guy Bormans, Koen Van Laere, Veerle Baekelandt (20226), Vunckx, Kathleen, Sarah-Ann Aelvoet (419667), Guy Bormans (419668), Baekelandt, Veerle, Van Laere, Koen, Veerle Baekelandt, Casteels, Cindy, Cindy Casteels, Michel Koole, Koen Van Laere (419669), Bormans, Guy, Sarah-Ann Aelvoet   +20 more
core   +1 more source

The Anti-Inflammatory Effects of Lipoxygenase and Cyclo-Oxygenase Inhibitors in Inflammation-Induced Human Fetal Glia Cells and the Aβ Degradation Capacity of Human Fetal Astrocytes in an Ex vivo Assay

Frontiers in Neuroscience, 2017
Chronic inflammation is a common phenomenon present in the background of multiple neurodegenerative diseases, including Alzheimer's disease (AD). The arachidonic acid pathway overproduces proinflammatory eicosanoids during these states and glial cells in
Rea Pihlaja, Rea Pihlaja, Merja Haaparanta-Solin, Merja Haaparanta-Solin, Juha O. Rinne   +4 more
doaj   +1 more source

Conheça seu PET [PDF]

, 2020
PET-Economia vem cumprindo o seu papel e contribuindo para a melhoria da graduação.
PET - Economia UFCG
core   +1 more source

Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation

EJNMMI Research, 2019
Background Positron emission tomography (PET) can be used for in vivo evaluation of the pathology associated with multiple sclerosis. We investigated the use of longitudinal PET imaging and the 18-kDa translocator protein (TSPO) binding radioligand [18F ...
S. K. Vainio, A. M. Dickens, J. Tuisku, O. Eskola, O. Solin, E. Löyttyniemi, D. C. Anthony, J. O. Rinne, L. Airas, M. Haaparanta-Solin   +9 more
doaj   +1 more source

Quality control of small animal PET scanner: The Brazilian Scenario

Brazilian Journal of Radiation Sciences, 2020
This work aims to evaluate the quality control program for small animal PET (positron emission tomography) scanners in Brazil. A questionnaire focused on type of small animal PET scanner and quality assurance program was prepared and sent to all ...
Rodrigo Modesto Gadelha Gontijo, Andréa Vidal Ferreira, Juliana Batista Silva, Marcelo Mamede   +3 more
doaj   +1 more source

Molecular Imaging and the PD-L1 Pathway: From Bench to Clinic

Frontiers in Oncology, 2021
Programmed death-1 (PD-1) and programmed death ligand 1 (PD-L1) inhibitors target the important molecular interplay between PD-1 and PD-L1, a key pathway contributing to immune evasion in the tumor microenvironment (TME).
David Leung, Samuel Bonacorsi, Ralph Adam Smith, Wolfgang Weber, Wendy Hayes   +4 more
doaj   +1 more source

Development of Novel Fluorine-18 Labeled PET Radioligands for Monoamine Oxidase B (MAO-B) [PDF]

, 2013
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and ...
Nag, Sangram
core   +1 more source

Performance of nanoScan PET/CT and PET/MR for quantitative imaging of 18F and 89Zr as compared with ex vivo biodistribution in tumor-bearing mice

EJNMMI Research, 2021
Introduction The assessment of ex vivo biodistribution is the preferred method for quantification of radiotracers biodistribution in preclinical models, but is not in line with current ethics on animal research.
Marion Chomet, Maxime Schreurs, Ricardo Vos, Mariska Verlaan, Esther J. Kooijman, Alex J. Poot, Ronald Boellaard, Albert D. Windhorst, Guus AMS van Dongen, Danielle J. Vugts, Marc C. Huisman, Wissam Beaino   +11 more
doaj   +1 more source