Results 21 to 30 of about 59,711 (283)

Simplified and accessible [18 F]F-AraG synthesis procedure for preclinical PET. [PDF]

open access: yesJ Labelled Comp Radiopharm, 2022
The PET tracer [18F]F-AraG, an arabinosyl guanine analog, has shown promise for visualizing activated T cells in multiple diseases. Herein, a practitioner's protocol is described, in which the PET tracer is prepared using minimal equipment and manual ...
Högnäsbacka AA   +3 more
europepmc   +2 more sources

Digital PET/MRI for preclinical applications

open access: yes, 2016
Combining different medical imaging modalities into a single device is a promising way to attain comprehensive and complementary information. Hybrid imaging modalities thus enable new research methods, improve diagnostic accuracy, and improve clinical workflow.
Weissler, Bjoern
openaire   +2 more sources

Standardization of Preclinical PET/CT Imaging to Improve Quantitative Accuracy, Precision, and Reproducibility: A Multicenter Study. [PDF]

open access: yesJ Nucl Med, 2020
Preclinical PET/CT is a well-established noninvasive imaging tool for studying disease development/progression and the development of novel radiotracers and pharmaceuticals for clinical applications.
McDougald W   +13 more
europepmc   +2 more sources

Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation

open access: yesEJNMMI Research, 2022
Highlights In a focal rat DTH-EAE model of neuroinflammation, dimethyl fumarate decreases the uptake of TSPO PET tracer [18F]GE-180 in the short term. Long-term [18F]GE-180 follow-up did not indicate a treatment effect.
S. K. Vainio   +10 more
doaj   +1 more source

[18F]Fluoride uptake in various bone types and soft tissues in rat

open access: yesEJNMMI Research, 2023
Background In the development of new 18F-labelled tracers, it is important to assess the amount of released [18F]fluoride taken up in the bones of experimental animals because all 18F-labelled PET-tracers are prone, to lesser or higher degree, to undergo
Nina Savisto   +8 more
doaj   +1 more source

Proposal of Brazilian National Program for Quality Control in the small animal PET scanners

open access: yesBrazilian Journal of Radiation Sciences, 2022
In Brazil, currently there are six preclinical molecular imaging centers and seven different small animal PET systems in use. However, there is still no national specific legislation for research laboratories focused on preclinical molecular images ...
Rodrigo Modesto Gadelha Gontijo
doaj   +1 more source

Efficiency of 124I radioisotope production from natural and enriched tellurium dioxide using 124Te(p,xn)124I reaction

open access: yesEJNMMI Physics, 2022
Background 124I Iodine (T $$_{1/2}$$ 1 / 2 = 4.18 d) is the only long-life positron emitter radioisotope of iodine that may be used for both imaging and therapy as well as for 131I dosimetry.
Paweł Bzowski   +9 more
doaj   +1 more source

Performance based on NEMA NU-4 2008 Standard of CDTN/CNEN’s Small Animal PET Scanner

open access: yesBrazilian Journal of Radiation Sciences, 2022
This study aimed to evaluate the general performance of the preclinical PET scanner (LabPET Solo 4, GE) at CDTN/CNEN using the NEMA NU 4-2008 protocol.
Rodrigo Modesto Gadelha Gontijo   +3 more
doaj   +1 more source

Preclinical and Translational PET/MR Imaging [PDF]

open access: yesJournal of Nuclear Medicine, 2014
Combined PET and MR imaging (PET/MR imaging) has progressed tremendously in recent years. The focus of current research has shifted from technologic challenges to the application of this new multimodal imaging technology in the areas of oncology, cardiology, neurology, and infectious diseases.
H. F. Wehrl   +9 more
openaire   +2 more sources

Standardisation of preclinical PET/CT protocols across multiple research centres [PDF]

open access: yes, 2020
Preclinical Positron Emission Tomography/Computed Tomography (PET/CT) is a well-established non-invasive imaging tool for studying disease development/progression, the development of novel radiotracers and pharmaceuticals for clinical applications ...
McDougald, Wendy Anne
core   +1 more source

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