Results 31 to 40 of about 59,711 (283)

Comparative analysis of image quality parameters and spatial resolution of three Small Animal PET scanner in Brazil

open access: yesBrazilian Journal of Radiation Sciences, 2023
This study evaluated Image Quality (IQ) parameters and spatial resolution (SR) of Triumph® LabPET systems installed in three different Brazilian preclinical molecular imaging centers.
Rodrigo Modesto Gadelha Gontijo   +8 more
doaj   +1 more source

ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein

open access: yesTranslational Neurodegeneration, 2022
Background Hijacking the transferrin receptor (TfR) is an effective strategy to transport amyloid-beta (Aβ) immuno-positron emission tomography (immunoPET) ligands across the blood–brain barrier (BBB).
Gillian Bonvicini   +5 more
doaj   +1 more source

Preclinical Evaluation of Novel PET Probes for Dementia

open access: yesSeminars in Nuclear Medicine, 2023
The development of novel PET imaging agents that selectively bind specific dementia-related targets can contribute significantly to accurate, differential and early diagnosis of dementia causing diseases and support the development of therapeutic agents.
Romy Cools   +3 more
openaire   +3 more sources

PET Imaging in Animal Models of Alzheimer’s Disease

open access: yesFrontiers in Neuroscience, 2022
The successful development and translation of PET imaging agents targeting β-amyloid plaques and hyperphosphorylated tau tangles have allowed for in vivo detection of these hallmarks of Alzheimer’s disease (AD) antemortem.
Baosheng Chen   +6 more
doaj   +1 more source

Preclinical NEMA image quality phantom PET data

open access: yes, 2021
This is a preclinical positron emission tomography (PET) dataset containing the list-mode data of a NEMA image quality phantom measured with the preclinical Siemens Inveon PET scanner.
Wettenhovi, Ville-Veikko,University of Eastern Finland   +1 more
core   +1 more source

PET performance evaluation of a preclinical digital PET/MRI insert [PDF]

open access: yesEJNMMI Physics, 2014
In recent years, several groups have presented combined PET/MRI devices for clinical and preclinical research. Using new technologies like SiPMs, the performance of the systems improved over the years allowing a detailed exploration of the relatively new field of hybrid imaging modality.
Schug, David   +9 more
openaire   +2 more sources

PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging

open access: yesFrontiers in Neuroscience, 2022
The development of novel PET imaging agents for synaptic vesicle glycoprotein 2A (SV2A) allowed for the in vivo detection of synaptic density changes, which are correlated with the progression and severity of a variety of neuropsychiatric diseases. While
Takuya Toyonaga   +6 more
doaj   +1 more source

Preclinical antibody-PET imaging of PD-L1

open access: yesFrontiers in Nuclear Medicine, 2022
Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade, including antibody therapeutics, has transformed cancer treatment. However, a major challenge in the field relates to selecting patients who are likely to respond to immune checkpoint inhibitors.
Brown, Emma L.   +3 more
openaire   +2 more sources

NEMA NU 4-2008 and in vivo imaging performance of RAYCAN trans-PET/CT X5 small animal imaging system [PDF]

open access: yes, 2022
The RAYCAN Trans-PET/CT X5 is a preclinical positron emission tomography and computed tomography (PET/CT) system intended for in vivo imaging of rats and mice, featuring all-digital readout electronics for PET data acquisition.The National Electrical ...
Q Xie   +13 more
core   +1 more source

Construction and Evaluation of Quantitative Small-Animal PET Probabilistic Atlases for [18F]FDG and [18F]FECT Functional Mapping of the Mouse Brain [PDF]

open access: yes, 2013
Automated voxel-based or pre-defined volume-of-interest (VOI) analysis of small-animal PET data in mice is necessary for optimal information usage as the number of available resolution elements is limited. We have mapped metabolic ([18F]FDG) and dopamine
Kathleen Vunckx (419666)   +20 more
core   +1 more source

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