Results 31 to 40 of about 59,711 (283)
This study evaluated Image Quality (IQ) parameters and spatial resolution (SR) of Triumph® LabPET systems installed in three different Brazilian preclinical molecular imaging centers.
Rodrigo Modesto Gadelha Gontijo +8 more
doaj +1 more source
Background Hijacking the transferrin receptor (TfR) is an effective strategy to transport amyloid-beta (Aβ) immuno-positron emission tomography (immunoPET) ligands across the blood–brain barrier (BBB).
Gillian Bonvicini +5 more
doaj +1 more source
Preclinical Evaluation of Novel PET Probes for Dementia
The development of novel PET imaging agents that selectively bind specific dementia-related targets can contribute significantly to accurate, differential and early diagnosis of dementia causing diseases and support the development of therapeutic agents.
Romy Cools +3 more
openaire +3 more sources
PET Imaging in Animal Models of Alzheimer’s Disease
The successful development and translation of PET imaging agents targeting β-amyloid plaques and hyperphosphorylated tau tangles have allowed for in vivo detection of these hallmarks of Alzheimer’s disease (AD) antemortem.
Baosheng Chen +6 more
doaj +1 more source
Preclinical NEMA image quality phantom PET data
This is a preclinical positron emission tomography (PET) dataset containing the list-mode data of a NEMA image quality phantom measured with the preclinical Siemens Inveon PET scanner.
Wettenhovi, Ville-Veikko,University of Eastern Finland +1 more
core +1 more source
PET performance evaluation of a preclinical digital PET/MRI insert [PDF]
In recent years, several groups have presented combined PET/MRI devices for clinical and preclinical research. Using new technologies like SiPMs, the performance of the systems improved over the years allowing a detailed exploration of the relatively new field of hybrid imaging modality.
Schug, David +9 more
openaire +2 more sources
The development of novel PET imaging agents for synaptic vesicle glycoprotein 2A (SV2A) allowed for the in vivo detection of synaptic density changes, which are correlated with the progression and severity of a variety of neuropsychiatric diseases. While
Takuya Toyonaga +6 more
doaj +1 more source
Preclinical antibody-PET imaging of PD-L1
Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade, including antibody therapeutics, has transformed cancer treatment. However, a major challenge in the field relates to selecting patients who are likely to respond to immune checkpoint inhibitors.
Brown, Emma L. +3 more
openaire +2 more sources
NEMA NU 4-2008 and in vivo imaging performance of RAYCAN trans-PET/CT X5 small animal imaging system [PDF]
The RAYCAN Trans-PET/CT X5 is a preclinical positron emission tomography and computed tomography (PET/CT) system intended for in vivo imaging of rats and mice, featuring all-digital readout electronics for PET data acquisition.The National Electrical ...
Q Xie +13 more
core +1 more source
Construction and Evaluation of Quantitative Small-Animal PET Probabilistic Atlases for [18F]FDG and [18F]FECT Functional Mapping of the Mouse Brain [PDF]
Automated voxel-based or pre-defined volume-of-interest (VOI) analysis of small-animal PET data in mice is necessary for optimal information usage as the number of available resolution elements is limited. We have mapped metabolic ([18F]FDG) and dopamine
Kathleen Vunckx (419666) +20 more
core +1 more source

