Results 11 to 20 of about 81,575 (289)

Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic preconditioning

open access: yesNeural Regeneration Research, 2020
Hypoxic preconditioning has been shown to improve hypoxic tolerance in mice, accompanied by the downregulation of DNA methyltransferases (DNMTs) in the brain.
Na Liu   +11 more
doaj   +1 more source

Effects of Preconditioning on RBC Deformability in Critically Ill Patients

open access: yesCritical Care Explorations, 2022
OBJECTIVES:. RBCs from critically ill patients have depressed deformability, especially in sepsis. Prolonged exposure of RBCs from healthy volunteers to physiologic shear stress (the preconditioning technique) has been associated with improved ...
Anthony Moreau, MD   +3 more
doaj   +1 more source

Preconditioning with associated blocking of Ca2+ inflow alleviates hypoxia-induced damage to pancreatic β-cells. [PDF]

open access: yesPLoS ONE, 2013
Beta cells of pancreatic islets are susceptible to functional deficits and damage by hypoxia. Here we aimed to characterize such effects and to test for and pharmacological means to alleviate a negative impact of hypoxia.Rat and human pancreatic islets ...
Zuheng Ma   +6 more
doaj   +1 more source

A study of optimal concentration range and time window of sevoflurane preconditioning for brain protection in MCAO rats

open access: yesBMC Anesthesiology, 2020
Background Sevoflurane preconditioning improves brain function in MCAO rats, and there are several methods for determining appropriate concentration and time windows for preconditioning.
Ying Deng   +6 more
doaj   +1 more source

Research on the Changes to the Lipid/Polymer Membrane Used in the Acidic Bitterness Sensor Caused by Preconditioning

open access: yesSensors, 2016
A taste sensor that uses lipid/polymer membranes can evaluate aftertastes felt by humans using Change in membrane Potential caused by Adsorption (CPA) measurements.
Yuhei Harada   +4 more
doaj   +1 more source

The Mechanisms of Peripheral Nerve Preconditioning Injury on Promoting Axonal Regeneration

open access: yesNeural Plasticity, 2021
Two major factors contribute to the failure of axonal regrowth in the central nervous system (CNS), namely, the neuronal intrinsic regenerative capacity and the extrinsic local inhibitory microenvironments.
Xiaoyan Yang   +4 more
doaj   +1 more source

Preconditioning as a method of neuroprotection in a model of brain infarct

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Preconditioning of ischemic and hypoxic type was investigated as a method of protecting brain against acute ischemic injury. The preconditioning methods were applied to experimental rats 24 h before the time when local brain infarct was done by middle ...
R. M. Khudoerkov   +4 more
doaj   +1 more source

Ischemic preconditioning

open access: yesVojnosanitetski pregled, 2005
Background. Ischemic preconditioning is a phenomenon during which myocardium, subjected to brief episodes of ischemia followed by reperfusion, tolerates better the subsequent, more prolonged episode of this ischemia, thus reducing the infarction size substantially. Case report.
Ristić-Anđelkov Anđelka   +3 more
openaire   +3 more sources

Ischemic preconditioning modifies mortality and inflammatory response [PDF]

open access: yesActa Cirúrgica Brasileira, 2016
PURPOSE: To evaluate the effect of ischemic preconditioning on mortality, inflammatory mediators and oxidative stress after intestinal ischemia and reperfusion.
Daniel Faria de Campos Pinheiro   +7 more
doaj   +2 more sources

DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation

open access: yesiScience, 2021
Summary: The “preconditioning effect” in AKI is a phenomenon in which an episode of ischemia-reperfusion results in tolerance to subsequent ischemia-reperfusion injury. However, its relationship between DNA damage repair has not been elucidated. Here, we
Akihito Hishikawa   +13 more
doaj   +1 more source

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