Results 21 to 30 of about 45,342 (240)

Creatine phosphate preconditioning reduces ischemiareperfusion injury in isolated rat heart

Сеченовский вестник, 2021
Aim. To study the effect of simultaneous administration of creatine phosphate immediately before ischemia on cardiodynamic parameters and biomarkers of oxidative stress in the coronary venous blood flow during retrograde perfusion in an isolated rat ...
L. A. Gadjieva, S. B. Bolevich, V. Jakovlevich, I. A. Omarov, H. A. Ordashev, M. K. Kartashova   +5 more
doaj   +1 more source

Preconditioning in cardiac anesthesia…… where are we?

Annals of Cardiac Anaesthesia, 2019
Preconditioning, a milestone concept in the cardiovascular sciences introduced 32 years back by Murry. This concept opened a new era in the field of organ protection.
Ajita Suhrid Annachhatre, Suhrid R Annachhatre   +1 more
doaj   +1 more source

Extracellular Vesicles and Alveolar Epithelial-Capillary Barrier Disruption in Acute Respiratory Distress Syndrome: Pathophysiological Role and Therapeutic Potential

Frontiers in Physiology, 2021
Extracellular vesicles (EVs) mediate intercellular communication by transferring genetic material, proteins and organelles between different cells types in both health and disease. Recent evidence suggests that these vesicles, more than simply diagnostic
Sergio Esquivel-Ruiz, Sergio Esquivel-Ruiz, Paloma González-Rodríguez, Paloma González-Rodríguez, José A. Lorente, José A. Lorente, José A. Lorente, Francisco Pérez-Vizcaíno, Francisco Pérez-Vizcaíno, Raquel Herrero, Raquel Herrero, Laura Moreno, Laura Moreno   +12 more
doaj   +1 more source

Preconditioned Mesenchymal Stromal Cells to Improve Allotransplantation Outcome

Cells, 2021
Mesenchymal stromal cells (MSCs) are tissue-derived progenitor cells with immunomodulatory as well as multilineage differentiation capacities, and have been widely applied as cellular therapeutics in different disease systems in both preclinical models ...
Hui-Yun Cheng, Madonna Rica Anggelia, Cheng-Hung Lin, Chih-Fan Lin   +3 more
doaj   +1 more source

Preconditioning with Low-Dose Radiation Improves Antitumor Immunity and Survival in DC-Vaccinated Mice

Life
Preconditioning regimens are essential for the immunologic success of cell therapies like CAR T cells. Nevertheless, their effect on cancer vaccines is underexplored, and preconditioning regimens are generally absent from cancer vaccine clinical trials ...
Eric Kwon, Shelby Namen, Colin J. Willoughby, Solomon Kang, Gaurav Pandey, Alexander B. Kim, Carl J. DeSelm   +6 more
doaj   +1 more source

Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content

International Journal of Cardiology: Heart & Vasculature, 2015
Background: Extracellular vesicles (EVs) are thought to exert protective effects after ischemic and remote ischemic preconditioning. It is not well understood which EV content factors are most relevant for protective effects. We hypothesize that ischemic
Kristina Svennerholm, Pouria Rodsand, Urban Hellman, Marie Lundholm, Anders Waldenström, Björn Biber, Gunnar Ronquist, Michael Haney   +7 more
doaj   +1 more source

Effects of preconditioning with TNFα and IFNγ in angiogenic potential of mesenchymal stromal cell-derived extracellular vesicles

Frontiers in Cell and Developmental Biology, 2023
Introduction: Mesenchymal stromal cells (MSCs) have demonstrated therapeutic properties both in vitro and in vivo to treat various diseases, including anti-inflammatory, immunomodulatory and pro-angiogenic effects.
Sophie Cavallero, Samir Dekali, Nathalie Guitard, Héléne Théry, Carole Hélissey, Carole Hélissey, Sabine François   +6 more
doaj   +1 more source

Microstructural Characterization of Spheroidal Graphite Irons: A Study of the Effect of Preconditioning Treatment

Metals, 2022
The effect of preconditioning treatments on the control and improvement of spheroidal graphite iron (SGI) microstructure was evaluated. In the melt, 0.15% of Zr-(Ca, Al) FeSi preconditioner was added into different conditions.
António Pires, Sónia Simões, Leander Michels, Emmanuelle Ott, Cathrine Hartung, Carlos Silva Ribeiro   +5 more
doaj   +1 more source

Repetitive spreading depolarization induces gene expression changes related to synaptic plasticity and neuroprotective pathways

Frontiers in Cellular Neuroscience, 2023
Spreading depolarization (SD) is a slowly propagating wave of profound depolarization that sweeps through cortical tissue. While much emphasis has been placed on the damaging consequences of SD, there is uncertainty surrounding the potential activation ...
Michela Dell’Orco, Jordan E. Weisend, Nora I. Perrone-Bizzozero, Andrew P. Carlson, Russell A. Morton, David N. Linsenbardt, C. William Shuttleworth   +6 more
doaj   +1 more source

Ischemic and Pharmacological Preconditioning

Общая реаниматология, 2011
The review article deals with the problem of ischemic preconditioning, the universal physiological mechanism of cell protection from hypoxia. Preconditioning is the term used to describe a phenomenon of the enhanced tolerance of a cell to a damaging ...
V. V. Likhvantsev, V. V. Moroz, O. A. Grebenchikov, Yu. I., Gorokhovatsky, Yu. V. Zarzhetsky, S. S. Timoshin, D. I. Levikov, V. L. Shaibakova   +7 more
doaj   +1 more source