Results 11 to 20 of about 37,679 (252)
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Ibrain, EarlyView., 2023 This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju +7 more
wiley +1 more source
Effects of pregabalin and gabapentin on postoperative pain and opioid consumption after laparoscopic cholecystectomy [PDF]
Korean Journal of Anesthesiology, 2017 BackgroundGabapentin and pregabalin are antiepileptic drugs that are also used for chronic pain treatment. This study evaluated the effects of pregabalin and gabapentin on postoperative pain in patients undergoing laparoscopic cholecystectomy.MethodsA ...
Mohammad Eidy +5 more
doaj +1 more source
Do gabapentin or pregabalin directly modulate the µ receptor? [PDF]
PeerJ, 2021 Background Pregabalin and gabapentin improve neuropathic pain symptoms but there are emerging concerns regarding their misuse. This is more pronounced among patients with substance use disorder, particularly involving opioids.
Preeti Manandhar +4 more
doaj +2 more sources
Renal Replacement Therapy, 2022 Background Severe pregabalin intoxication may cause serious symptoms, such as coma. Since pregabalin is a small molecule with no protein binding sites and has low volume of distribution, hemodialysis can be effective in eliminating pregabalin from the ...
Takashi Shimazui +8 more
doaj +1 more source
Pregabalin effect on acute and chronic pain after cardiac surgery [PDF]
, 2017 Introduction. Pain after cardiac surgery affects long-term patient wellness. This study investigated the effect of preoperative pregabalin on acute and chronic pain after elective cardiac surgery with median sternotomy. Methods.
Arnaoutoglou, Elena +6 more
core +3 more sources
Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]
, 2020 Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core +1 more source
Reactions Weekly, 2018 Pregabalin is a second-generation antiepileptic drug characterized by few antiepileptic indications, with a very good interaction profile in polytherapy. The therapeutic indications of pregabalin for the treatment of epileptic seizures have been largely overshadowed by its widespread use for the treatment of anxiety disorders (especially generalized ...
C. Vidal, W.-R. Külpmann
+6 more sources
Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]
, 2016 INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina +6 more
core +2 more sources
Cells, 2022 Pregabalin is widely used as a treatment for multiple neurological disorders; however, it has been reported to have the potential for misuse. Due to a lack of safety studies in pregnancy, pregabalin is considered the last treatment option for various ...
Walaa F. Alsanie +15 more
doaj +1 more source