Results 71 to 80 of about 37,679 (252)

Brazilian Society of Surgical Oncology: Guidelines and Consensus Statement for Palliative Surgery in Oncology

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objective Palliative surgery in oncology aims to relieve symptoms, improve quality of life, and respect patient autonomy in advanced cancer. This study aimed to develop evidence‐based recommendations for safely indicating and performing palliative surgeries in Brazil, considering clinical, ethical, and multidisciplinary aspects.
Audrey Cabral Ferreira de Oliveira   +15 more
wiley   +1 more source

Perioperative gabapentin and pregabalin in cardiac surgery: a systematic review and meta-analysis

open access: yesRevista Brasileira de Anestesiologia
Objectives: Sternotomy for cardiac surgeries causes significant postoperative pain and when not properly managed may cause significant morbidity. As neuropathic pain is a significant component here, gabapentin and pregabalin may be effective in these ...
Souvik Maitra   +3 more
doaj   +1 more source

The Comparison of Gabapentin and Amitriptilin Effectivity as Pain Therapy in Herniated Nucleus Pulposus [PDF]

open access: yes, 2015
Herniated nucleus pulposus (HNP) is one of peripheral neuropathic pain. Although concensus guidelines for the treatment of neuropathic pain are based on the results of the RCT studies, there are still gaps in the literatures.
Cahyaningsih, I. (Indriastuti)   +2 more
core  

Pregabalin Misuse and Abuse: A Scoping Review of Extant Literature [PDF]

open access: yes
Prescribing of pregabalin is increasing worldwide with public health concerns centering on misuse and abuse of prescribed and diverted pregabalin. To describe and map what is known about misuse and abuse of pregabalin, a scoping review of available ...
Al-Husseini, A, van Hout, MC, Wazaify, M
core   +1 more source

Considerations and Tips for Promoting Skin Barrier Maintenance and Quality of Life in Patients With Diabetes Mellitus: An Expert Consensus

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Skin changes such as xerosis and pruritus are common complications among diabetes patients and may lead to serious adverse events such as diabetic foot syndrome and amputations. Evidence suggests that daily application of optimal skincare, including gentle cleansers and moisturizers, may help improve skin barrier function, preventing ...
Robert S. Kirsner   +5 more
wiley   +1 more source

Oral self-administration of pregabalin in a mouse model and the resulting drug addiction features

open access: yesSaudi Pharmaceutical Journal
Prescription drug abuse is an issue that is rapidly growing globally. Pregabalin, an anticonvulsant, analgesic, and anxiolytic medication, is effective in the management of multiple neurological disorders; however, there is increasing concern regarding ...
Yusuf S. Althobaiti
doaj   +1 more source

Long-term efficacy of OROS® hydromorphone combined with pregabalin for chronic non-cancer neuropathic pain. [PDF]

open access: yes, 2014
BACKGROUND AND OBJECTIVES: Treatment for chronic non-cancer neuropathic pain can be complicated by side effects and drug interactions. Combining opioid analgesics and calcium channel modulators may overcome these and improve efficacy.
Casali, M   +5 more
core   +1 more source

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu   +3 more
wiley   +1 more source

Pregabalin in acute and chronic pain

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2011
Pregabalin is a gamma-amino-butyric acid analog shown to be effective in several models of neuropathic pain, incisional injury, and inflammatory injury. In this review, the role of pregabalin in acute postoperative pain and in chronic pain syndromes has ...
Dalim Kumar Baidya   +3 more
doaj   +1 more source

Chronic pregabalin treatment protects against spreading depolarization and alters hippocampal synaptic characteristics in a model of familial hemiplegic migraine-type 1

open access: yesMolecular Brain, 2023
Familial hemiplegic migraine type-1 (FHM-1) is a form of migraine with aura caused by mutations in the P/Q-type (Cav2.1) voltage-gated calcium channel. Pregabalin, used clinically in the treatment of chronic pain and epilepsy, inhibits P/Q-type calcium ...
Stuart M. Cain   +10 more
doaj   +1 more source

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