Results 121 to 130 of about 10,479 (197)

Pregnane X Receptor Regulates Human Endocrine System by Inducing Sex Hormone-Binding Globulin Expression. [PDF]

Basic Clin Pharmacol Toxicol
Ahonen MH, Konzack A, Smutny T, Pavek P, Hakkola J, Hukkanen J.   +5 more
europepmc   +1 more source

Effects of Brazilian medicinal plants on the transcriptional activity of the pregnane X receptor in HeLa cells

, 2019
Dissertação (mestrado) — Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências Farmacêuticas, Brasília, 2019.Em 2008, o Ministério da Saúde do Brasil criou uma lista de plantas medicinais visando contribuir com a
Silva, Sarah Caroline de Souza
core  

Pregnane X receptor (NR1I2) deficiency in mice reveals context-dependent regulation of inflammatory homeostasis. [PDF]

Front Immunol
Amini SE.
europepmc   +1 more source

Pregnane X receptor mitigates aristolochic acid-induced acute kidney injury via p53 ubiquitination. [PDF]

Ren Fail
Liu Q, Deng F, Chen A, Liu Y.
europepmc   +1 more source

Pregnane X receptor activation remodels glucose metabolism to promote NAFLD development in obese mice. [PDF]

Mol Metab, 2023
Karpale M, Kummu O, Kärkkäinen O, Lehtonen M, Näpänkangas J, Herfurth UM, Braeuning A, Rysä J, Hakkola J.   +8 more
europepmc   +1 more source

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor. [PDF]

PLoS ONE, 2016
Marianne Mathäs, Christian Nusshag, Oliver Burk, Ute Gödtel-Armbrust, Holger Herlyn, Leszek Wojnowski, Björn Windshügel   +6 more
doaj   +1 more source

Subtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators. [PDF]

Structure
Huber AD, Garcia-Maldonado E, Lin W, Poudel S, Wu J, Miller DJ, Chen T.   +6 more
europepmc   +1 more source

The F-box-only protein 44 regulates pregnane X receptor protein level by ubiquitination and degradation. [PDF]

Acta Pharm Sin B, 2023
Florke Gee RR, Huber AD, Wu J, Bajpai R, Loughran AJ, Pruett-Miller SM, Chen T.   +6 more
europepmc   +1 more source

Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis. [PDF]

Front Pharmacol
Rao S, Mei Y, Shi L, Li H, Zhou M, Meng Z, Zhao Z, Li S, Sun W, Tian Q.   +9 more
europepmc   +1 more source

Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway. [PDF]

CNS Neurosci Ther, 2023
Xuan LN, Hu ZX, Jiang ZF, Zhang C, Sun XW, Ming WH, Liu HT, Qiao RF, Shen LJ, Liu SB, Wang GY, Wen L, Luan ZL, Yin J.   +13 more
europepmc   +1 more source