Results 151 to 160 of about 18,065 (250)

QSAR development and profiling of 72,524 REACH substances for PXR activation and CYP3A4 induction [PDF]

, 2017
Abildgaard Rosenberg, Sine, Dybdahl, Marianne, Huang, R., Nikolov, Nikolai Georgiev, Wedebye, Eva Bay, Xia, M.   +5 more
core   +1 more source

Cytochrome P450 Induction and Xeno‐Sensing Receptors Pregnane X Receptor, Constitutive Androstane Receptor, Aryl Hydrocarbon Receptor and Peroxisome Proliferator‐Activated Receptor α at the Crossroads of Toxicokinetics and Toxicodynamics

, 2018
Jukka Hakkola, Camilla Bernasconi, Sandra Coecke, Lysiane Richert, Tommy B. Andersson, Olavi Pelkonen   +5 more
openalex   +1 more source

Binding of Per- and Poly- Fluoroalkyl Substances to Human Pregnane X Receptor [PDF]

, 2021
Yiğitcan Eken
openalex   +1 more source

Pregnane X receptor activation remodels glucose metabolism to promote NAFLD development in obese mice. [PDF]

Mol Metab, 2023
Karpale M, Kummu O, Kärkkäinen O, Lehtonen M, Näpänkangas J, Herfurth UM, Braeuning A, Rysä J, Hakkola J.   +8 more
europepmc   +1 more source

Cytoplasmic Localization of Pregnane X Receptor and Ligand-dependent Nuclear Translocation in Mouse Liver

, 2004
E. James Squires, Tatsuya Sueyoshi, Masahiko Negishi   +2 more
openalex   +1 more source

The F-box-only protein 44 regulates pregnane X receptor protein level by ubiquitination and degradation. [PDF]

Acta Pharm Sin B, 2023
Florke Gee RR, Huber AD, Wu J, Bajpai R, Loughran AJ, Pruett-Miller SM, Chen T.   +6 more
europepmc   +1 more source

Subtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators. [PDF]

Structure
Huber AD, Garcia-Maldonado E, Lin W, Poudel S, Wu J, Miller DJ, Chen T.   +6 more
europepmc   +1 more source

Pregnane X receptor (PXR) deficiency protects against spinal cord injury by activating NRF2/HO-1 pathway. [PDF]

CNS Neurosci Ther, 2023
Xuan LN, Hu ZX, Jiang ZF, Zhang C, Sun XW, Ming WH, Liu HT, Qiao RF, Shen LJ, Liu SB, Wang GY, Wen L, Luan ZL, Yin J.   +13 more
europepmc   +1 more source

A vinblastine fluorescent probe for pregnane X receptor in a time-resolved fluorescence resonance energy transfer assay

, 2013
Wenwei Lin, Taosheng Chen
openalex   +2 more sources

Notoginsenoside R1 Attenuates Experimental Inflammatory Bowel Disease via Pregnane X Receptor Activation [PDF]

, 2014
Jingjing Zhang, Lili Ding, Baocan Wang, Gaiyan Ren, Aning Sun, Chao Deng, Xiaohui Wei, Sridhar Mani, Zhengtao Wang, Wei Dou   +9 more
openalex   +1 more source