Results 61 to 70 of about 6,716 (130)

Molecular Signature of Cisplatin Resistance in Ovarian Cancer Identifies Therapeutic Opportunities for Re-sensitization. [PDF]

J Cancer
Mansour M, van Ginkel S, Alata M, Bani I, Elhussin I.   +4 more
europepmc   +1 more source

Subtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators. [PDF]

Structure
Huber AD, Garcia-Maldonado E, Lin W, Poudel S, Wu J, Miller DJ, Chen T.   +6 more
europepmc   +1 more source

RE: Factors affecting voriconazole pharmacokinetic variability in critically ill patients: a systematic review. [PDF]

Crit Care
Langbeen J, Vangheluwe T, Van Hoecke F, Dumoulin A, Vogelaers D.   +4 more
europepmc   +1 more source

Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis. [PDF]

Front Pharmacol
Rao S, Mei Y, Shi L, Li H, Zhou M, Meng Z, Zhao Z, Li S, Sun W, Tian Q.   +9 more
europepmc   +1 more source

Xenobiotic pregnane X receptor (PXR) regulates innate immunity via activation of NLRP3 inflammasome in vascular endothelial cells. [PDF]

J Biol Chem, 2014
Wang S, Lei T, Zhang K, Zhao W, Fang L, Lai B, Han J, Xiao L, Wang N.   +8 more
europepmc   +1 more source

Physiological Functions and Pathological Roles of PXR. [PDF]

J Endocr Soc
Ikeda K, Horie K, Inoue S, Blumberg B.
europepmc   +1 more source

Expression and Prognostic Implication of the Nuclear Receptors Farnesoid X Receptor and Pregnane X Receptor in Human Cholangiocarcinoma. [PDF]

Cancer Diagn Progn
Sa-Ngiamwibool P, Yoshinari K, Shizu R, Kongpetch S, Prawan A, Senggunprai L.   +5 more
europepmc   +1 more source

Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily. [PDF]

Curr Drug Metab, 2013
Smutny T, Mani S, Pavek P.
europepmc   +1 more source

Schisandrin B Targets PXR to Enhance Bile Acid Metabolism and Alleviate ANIT-Induced Cholestatic Liver Injury via Dual Pathways. [PDF]

Int J Biol Sci
Zhang Y, Lan H, Yu X, Zhuo L, Zhao B, Liu F, An L, Zhang F, Liu Z, Wang C.   +9 more
europepmc   +1 more source