Results 1 to 10 of about 668 (155)
Inhibition mechanism of alpha-amylase, a diabetes target, by a steroidal pregnane and pregnane glycosides derived from Gongronema latifolium Benth [PDF]
Alpha-amylase is widely exploited as a drug target for preventing postprandial hyperglycemia in diabetes and other metabolic diseases. Inhibition of this enzyme by plant-derived pregnanes is not fully understood.
Oludare M. Ogunyemi +13 more
doaj +2 more sources
Postnatal Dynamics of Circulating Steroid Hormones in Mule and Equine Neonates [PDF]
It is necessary to study hormonal patterns from mules to recognize alterations and neonatal maladaptation. Our objective was to evaluate concentrations of hormones in mule (n = 6) and equine foals (n = 6).
Yatta Linhares Boakari +6 more
doaj +2 more sources
Progestins - a review of clinical application in gynecology [PDF]
Aims Progestins are a group of substances with a wide range of applications. They are classified into pregnanes, estranes, and gonanes, and further divided into four generations based on their testosterone (TE) or progesterone (P4) origin.
Dominika Żyła +5 more
doaj +2 more sources
Pregnanes That Bind To The Digitalis Receptor
Steroid binding domains of Na,K-ATPase and the nuclear hormone receptors share amino acid sequence homologies. In a ouabain radioligand assay, the potencies of series of planar or bent steroid moieties suggest that the domain in Na,K-ATPase can accommodate compounds with a planar configuration.
F S Labella, J F Templeton
exaly +3 more sources
Dual targeting of cytokine storm and viral replication in COVID-19 by plant-derived steroidal pregnanes: An in silico perspective [PDF]
Gideon Gyebi +2 more
exaly +2 more sources
Geochemical research of asphaltite formation in the Orenburg region [PDF]
The results of the studies of the physicochemical properties and genesis of asphaltites from the deposits of the Orenburg region are considered. Based on the data of a study on the distribution of hydrocarbon biomarkers (n-alkanes, isoprenanes, steranes,
Zakharchenko Maria +2 more
doaj +1 more source
Polyoxypregnane Ester Derivatives and Lignans from Euphorbia gossypina var. coccinea Pax.
From the aerial parts of Euphorbiagossypina var. coccinea Pax., eight new pregnane glycosides (euphogossypins A–H, 1–8) of the cynanforidine and deacetylmetaplexigenin aglycons, two new lignans (gossypilignans A and B, 9 and 10), and four known compounds,
Reham Hammadi +8 more
doaj +1 more source
Pregnane glycosides constitute a class of compounds widely distributed in the plant kingdom. Many of them have shown either anticarcinogenic or cancer inhibitory properties, besides other useful biological activities. New chromatographic techniques and advances in spectroscopic and spectrometric methods have accelerated the purification and structure ...
Nilendu Panda +3 more
openaire +1 more source
Macrosiphonia petraea (A. St.-Hil.) Kuntze is a plant popularly known as "velame". Its root infusion is used in the folk medicine of Mato Grosso do Sul, Brazil, for the treatment of inflammatory diseases.
Luiz Roberto de Assis Junior +3 more
doaj +3 more sources
Exploration of diacerein as a neuroprotective adjuvant to Adenium obesum: An in-vivo study
Background: Since the dawn of civilization, medicinal plants have been essential in the treatment of numerous human ailments. Medicinal plants have been the reliable sources to treat various diseases.
Neeraj Kumar Sharma, Kislaya Mishra
doaj +1 more source

