Results 11 to 20 of about 661 (149)
Inhibition mechanism of alpha-amylase, a diabetes target, by a steroidal pregnane and pregnane glycosides derived from Gongronema latifolium Benth. [PDF]
Front Mol Biosci, 2022 Alpha-amylase is widely exploited as a drug target for preventing postprandial hyperglycemia in diabetes and other metabolic diseases. Inhibition of this enzyme by plant-derived pregnanes is not fully understood.
Ogunyemi OM +11 more
europepmc +2 more sources
Postnatal Dynamics of Circulating Steroid Hormones in Mule and Equine Neonates. [PDF]
Vet Sci, 2022 It is necessary to study hormonal patterns from mules to recognize alterations and neonatal maladaptation. Our objective was to evaluate concentrations of hormones in mule (n = 6) and equine foals (n = 6).
Boakari YL +6 more
europepmc +2 more sources
Progestins - a review of clinical application in gynecology. [PDF]
Ann MedAims Progestins are a group of substances with a wide range of applications. They are classified into pregnanes, estranes, and gonanes, and further divided into four generations based on their testosterone (TE) or progesterone (P4) origin.
Żyła D +5 more
europepmc +2 more sources
Pregnanes That Bind To The Digitalis Receptor
Clinical and Experimental Hypertension, 1998 Steroid binding domains of Na,K-ATPase and the nuclear hormone receptors share amino acid sequence homologies. In a ouabain radioligand assay, the potencies of series of planar or bent steroid moieties suggest that the domain in Na,K-ATPase can accommodate compounds with a planar configuration.
John F Templeton
exaly +3 more sources
Geochemical research of asphaltite formation in the Orenburg region [PDF]
E3S Web of Conferences, 2019 The results of the studies of the physicochemical properties and genesis of asphaltites from the deposits of the Orenburg region are considered. Based on the data of a study on the distribution of hydrocarbon biomarkers (n-alkanes, isoprenanes, steranes,
Zakharchenko Maria +2 more
doaj +1 more source
Polyoxypregnane Ester Derivatives and Lignans from Euphorbia gossypina var. coccinea Pax.
Plants, 2022 From the aerial parts of Euphorbiagossypina var. coccinea Pax., eight new pregnane glycosides (euphogossypins A–H, 1–8) of the cynanforidine and deacetylmetaplexigenin aglycons, two new lignans (gossypilignans A and B, 9 and 10), and four known compounds,
Reham Hammadi +8 more
doaj +1 more source
Natural Product Communications, 2006 Pregnane glycosides constitute a class of compounds widely distributed in the plant kingdom. Many of them have shown either anticarcinogenic or cancer inhibitory properties, besides other useful biological activities. New chromatographic techniques and advances in spectroscopic and spectrometric methods have accelerated the purification and structure ...
Nilendu Panda +3 more
openaire +1 more source
Química Nova, 2013 Macrosiphonia petraea (A. St.-Hil.) Kuntze is a plant popularly known as "velame". Its root infusion is used in the folk medicine of Mato Grosso do Sul, Brazil, for the treatment of inflammatory diseases.
Luiz Roberto de Assis Junior +3 more
doaj +3 more sources
Exploration of diacerein as a neuroprotective adjuvant to Adenium obesum: An in-vivo study
Journal of Ayurveda and Integrative Medicine, 2023 Background: Since the dawn of civilization, medicinal plants have been essential in the treatment of numerous human ailments. Medicinal plants have been the reliable sources to treat various diseases.
Neeraj Kumar Sharma, Kislaya Mishra
doaj +1 more source
Estudo químico das folhas de Trichilia silvatica (Meliaceae)
Química Nova, 2014 From the leaves of a specimen of Trichilia silvatica Meliaceae, eight known compounds were isolated, namely, two pregnanes, 2α,3β,4β-trihydroxypregnan-16-one (1) and 2β,3β,4β-trihydroxypregnan-16-one (2), three diterpenes, cneorubine X (3), kolavelool (4)
Aloízio de Oliveira Soares +5 more
doaj +1 more source