Results 11 to 20 of about 668 (155)
Estudo químico das folhas de Trichilia silvatica (Meliaceae)
Química Nova, 2014 From the leaves of a specimen of Trichilia silvatica Meliaceae, eight known compounds were isolated, namely, two pregnanes, 2α,3β,4β-trihydroxypregnan-16-one (1) and 2β,3β,4β-trihydroxypregnan-16-one (2), three diterpenes, cneorubine X (3), kolavelool (4)
Aloízio de Oliveira Soares +5 more
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Pregnanes and Pregnane Glycosides from Hoya carnosa.
Chemical and Pharmaceutical Bulletin, 1999 Eleven pregnanes were isolated from the hydrolysate of the CHCl3 extract fractionated from the caules of Hoya carnosa. Among these, six pregnanes, including 19-acetoxydigipurpurogenin II, were new, and their structures were elucidated. The structures of twenty new pregnane tetraosides and pentaosides, named hoyacarnosides A-T, besides three known ones ...
ABE, Fumiko +5 more
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BMC Cancer, 2003 Background Recent observations indicate that human tumorous breast tissue metabolizes progesterone differently than nontumorous breast tissue. Specifically, 5α-reduced metabolites (5α-pregnanes, shown to stimulate cell proliferation and detachment) are ...
Lewis Michael J, Wiebe John P
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Patterns of endogenous steroids in apathetic refugee children are compatible with long-term stress
BMC Research Notes, 2012 Background During the last few years, a number of children of asylum applicants in Sweden developed an apathetic or unconscious state. The syndrome was perceived as new, and various explanations were advanced such as factitious disorder, intoxication, or
Söndergaard Hans +4 more
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Pharmaceutical Biology, 2017 Context: Balanites aegyptiaca Del. (Zygophyllaceae) fruits are well-known antidiabetic drug in Egyptian folk medicine. Nevertheless, its mechanism of action is still unclear.
Shahira Mohammed Ezzat +2 more
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Pregnane and pregnane glycosides from Trachelospermum liukiuense.
Chemical and Pharmaceutical Bulletin, 1989 Cortexone and three new bisdesmosidic glycosides of teikagenin were isolated from Trachelospermum liukiuense, together with five glycosides already known in Trachelospermum asiaticum. The new glycosides have D-digitalose linked to the 20-OH as well as to the 3-OH.
ABE, Fumiko, YAMAUCHI, Tatsuo
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Molecules, 2009 A series of epoxy- and/or 20-oxime pregnanes were synthesized from commercially available pregnenolone. Compounds 1, 3, 7, 8 and 11-13 were evaluated for cytotoxicity activity towards LNCaP (androgen-dependent) and PC-3 (androgenindependent) prostate ...
Sujeong Kim, Eunsook Ma
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Pregnane and Pregnane Glycosides from the Malagasy Plant, Cynanchum aphyllum.
ChemInform, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
Kanchanapoom, Tripetch +4 more
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Menopausal hormone therapy and venous thromboembolism
Menopause Review, 2014 Menopausal hormone therapy (MHT) is the most effective method of treating vasomotor symptoms and other climacteric symptoms related to estrogen deficiency in peri- and postmenopausal period.
Małgorzata Bińkowska
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Role of aldo-keto reductase enzymes in mediating the timing of parturition
Frontiers in Pharmacology, 2012 A better understanding of the mechanisms underlying the initiation of parturition would provide an important step towards the development of more effective therapies for the prevention of pre-term labor and the associated neonatal morbidity and mortality.
Michael C. Byrns
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