Results 41 to 50 of about 15,454 (206)

Evaluation of a commercial automated assay for rapid serum progesterone determination in cattle, sheep and goats

Veterinary Record, EarlyView.
Abstract Background In ruminants, information on serum progesterone concentrations can be important in monitoring the oestrous cycle for pregnancy testing and the detection of endocrine disorders. We aimed to evaluate the suitability of a commercial enzyme‐linked fluorescence assay (ELFA), the MINI VIDAS (bioMérieux, Nürtingen), for measuring ...
Lina Längerer, Gerhard Schuler, Henrik Wagner, Kathrin Büttner, Axel Wehrend   +4 more
wiley   +1 more source

Cellular and molecular mechanisms of neurosteroids in various parts of the central nervous system of rats (part I)

Якутский медицинский журнал
Neuroactive steroids are a class of endogenous steroids synthesized in the nervous tissue and / or capable of having a modulating effect on its functional activity in the brain.
D. V. Dmitrenko, S. N. Zobova, T. G. Ruksha, T. I. Prusova, A. A. Usoltseva   +4 more
doaj   +1 more source

Synthesis and Evaluation of Some 17-Acetamidoandrostane and N,N-Dimethyl-7-deoxycholic Amide Derivatives as Cytotoxic Agents: Structure/Activity Studies

Molecules, 2013
Using pregnenolone and 7-deoxycholic acid as starting materials, some 17-acetamidoandrostane and N,N-dimethyl-7-deoxycholic amide derivatives were synthesized. The cytotoxicity of the synthesized compounds was tested in vitro against two tumor cell lines:
Aimin Zhou, Chun Zeng, Huacan Song, Chunfang Gan, Linyi Jia, Jianguo Cui, Yanmin Huang   +6 more
doaj   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

Electrocatalytic Polarity Inversion of Azlactones: Access to α‐Quaternary Amino Acids with Electron‐Rich SOMOphiles

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez, David Buedo, Alberto Vega‐Peñaloza, Kian Gosling, Stuart C. D. Kennington, Bart Limburg, Xavier Companyó   +6 more
wiley   +2 more sources

Neurosteroids Progesterone and Dehydroepiandrosterone: Molecular Mechanisms of Action in Neuroprotection and Neuroinflammation

Pharmaceuticals
Neurosteroids pregnenolone, progesterone, allopregnanolone, and dehydroepiandrosterone have been actively studied in the last years as candidates for the treatment of neurodegenerative diseases and postinjury rehabilitation.
Tatiana A. Fedotcheva, Nikolay L. Shimanovsky   +1 more
doaj   +1 more source

Gonadal Development–Related Genes and a Male‐Specific Genetic Marker Identified in the Endangered Sichuan Taimen (Hucho bleekeri)

Integrative Zoology, EarlyView.
Integrated transcriptomic and proteomic analyses were used to validate gonadal development–related genes and to identify a sex‐specific molecular marker in Hucho bleekeri. ABSTRACT Sex determination and differentiation represent fundamental topics in reproductive biology. Sichuan taimen (Hucho bleekeri), a first‐class national protected fish species in
Qinyao Wei, Hua Li, Yeyu Chen, Huanchao Yang, Jun Du, Zhaobin Song   +5 more
wiley   +1 more source

Niemann-Pick Type C2 protein contributes to the transport of endosomal cholesterol to mitochondria without interacting with NPC1[S]

Journal of Lipid Research, 2012
Mitochondrial cholesterol is maintained within a narrow range to regulate steroid and oxysterol synthesis and to ensure mitochondrial function. Mitochondria acquire cholesterol through several pathways from different cellular pools.
Barry E. Kennedy, Mark Charman, Barbara Karten   +2 more
doaj   +1 more source

Adenosine—A Regulator of Human Testicular Peritubular Cells

Andrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz, Annika Liebich, Youli Stepanov, Jan B. Stöckl, Mirko Peitzsch, Michaela Schneider, Julia Schneider, Nicole Kreitmair, Matthias Trottmann, Frank‐Michael Köhn, Jovica Ninkovic, Thomas Fröhlich, Artur Mayerhofer   +12 more
wiley   +1 more source

Maternal steroids during pregnancy and their associations with ambient air pollution and temperature during preconception and early gestational periods

Environment International, 2022
Hormones play critical roles in facilitating pregnancy progression and the onset of parturition. Several classes of environmental contaminants, including fine particulate matter (PM2.5) and ambient temperature, have been shown to alter hormone ...
Elena Colicino, Whitney Cowell, Nicolo Foppa Pedretti, Anu Joshi, Oulhote Youssef, Allan C. Just, Itai Kloog, Lauren Petrick, Megan Niedzwiecki, Robert O. Wright, Rosalind J. Wright   +10 more
doaj   +1 more source