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Prenatal antiseizure drug exposure and risk of neurodevelopmental disorders in children: population based cohort study.

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Straub L, Hernandez-Diaz S, Bateman BT, Zhu Y, Mogun H, Wisner KL, Gray KJ, Lester B, McDougle CJ, Pennell PB, Huybrechts KF.   +10 more
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Delayed Developmental Effects Following Prenatal Exposure to Drugs

Current Pharmaceutical Design, 2001
Increasing evidence points to the possible risks of delayed effects upon prenatal exposure to chemicals; the evaluation of such effects may pose serious problems to clinicians, epidemiologists and toxicologists. In fact, several systems (e.g., nervous, excretory) show important developmental processes well after the organogenetic period, up to the ...
A, Mantovani, G, Calamandrei
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Delayed neurochemical effects of prenatal exposure to MeHg in the cerebellum of developing rats

Toxicology Letters, 2018
Human fetuses and neonates are particularly vulnerable to methylmercury (MeHg)-induced brain damage and are sensitive even to low exposure levels. Previous work of our group evidence that prenatal exposure to MeHg causes cognitive and behavioral alterations and disrupt hippocampus signaling.
Luana, Heimfarth, Jeferson, Delgado, Moara Rodrigues, Mingori, Karla Suzana, Moresco, Regina Pessoa, Pureur, Daniel Pens, Gelain, José Cláudio Fonseca, Moreira   +6 more
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Prenatal Exposure to Ethanol Disrupts Spatial Memory: Effect of the Training–Testing Delay Period

Physiology & Behavior, 1998
The present study investigated how variations in the period of delay between training and testing in the Morris water maze task affect the use of spatial memory in adult rats that were prenatally exposed to ethanol. Previous results utilizing the Morris water maze task have shown that prenatal, or early postnatal, exposure to ethanol produces deficits ...
D B, Matthews, P E, Simson
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Delayed Effects of Prenatal or Postnatal Exposure to Diethylstilbestrol in the Adult Female Guinea Pig

Cells Tissues Organs, 1987
Of 25 mature female guinea pigs exposed transplacentally to diethylstilbestrol (DES) for more than 20 days before term, 8 showed abnormal changes in the genital tract (stimulation of the epithelium and stroma, cystic glandular hyperplasia of the endometrial glands near the junction of the upper endocervix and endometrium) and 9 showed severe changes ...
J, Davies, J, Lefkowitz
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Delayed effect of prenatal exposure to hypoxia on the susceptibility of rats to electric seizures

Doklady Biological Sciences, 2015
We studied the delayed effects of prenatal exposure to hypoxia on the susceptibility of rats to seizures. The later was estimated using graded electroshock. The experiments were performed in two groups of 1.5-year-old male Wistar rats. The experimental group consisted of the animals that were exposed to hypoxia on day 14 of prenatal development, and ...
D S, Kalinina, E V, Frolova, V V, Lavrentyeva, N M, Dubrovskaya, N Ya, Lukomskaya, K Kh, Kim, A V, Zaitsev, I A, Zhuravin, L G, Magazanik   +8 more
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The effect of prenatal chlordane exposure on the delayed hypersensitivity response of BALB/c mice

Toxicology Letters, 1985
Previous studies in our laboratory have indicated that in utero chlordane exposure caused a significant enhancement in the survival of the offspring to influenza virus infection. Further studies, reported here, show that the non-specific delayed type hypersensitivity (DTH) response to oxazolone at 100 days of age, but not at 30 days of age, was ...
J B, Barnett, L S, Soderberg, J H, Menna
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Effect of histochrome on the severity of delayed effects of prenatal exposure to lead nitrate in the rat brain

Bulletin of Experimental Biology and Medicine, 2008
The effects of histochrome on the severity of delayed effects of prenatal exposure to lead nitrate were studied in the rat brain. Exposure of pregnant rats to lead nitrate during activation of free radical oxidation reduced activity of NADH- and NADPH-dehydrogenases in cortical neurons of their 40-day-old progeny, reduced the number of neurons in a ...
B Ya, Ryzhavsky, O A, Lebedko, D S, Belolubskaya   +2 more
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