A quantitative study of neurochemically-defined populations of inhibitory interneurons in the superficial dorsal horn of the mouse spinal cord [PDF]
, 2017 Around a quarter of neurons in laminae I-II of the dorsal horn are inhibitory interneurons. These play an important role in modulating somatosensory information, including that perceived as pain or itch.
Boyle, Kieran A. +7 more
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Neurobiology of Disease, 2004 In parkinsonian patients as well as in primate models with levodopa-induced dyskinesias (LID), an increase in the expression of preproenkephalin in the striatal output pathways has been demonstrated.
Pershia Samadi +2 more
doaj +1 more source
Neurobiology of Disease, 2007 l-DOPA-induced dyskinesia (LID) is one of the main limitations of long term l-DOPA use in Parkinson’s disease (PD) patients. We show that chronic l-DOPA treatment induces novel dyskinetic behaviors in aphakia mouse with selective nigrostriatal deficit ...
Yunmin Ding +5 more
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A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. [PDF]
, 2015 Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role in ...
Blasio, Angelo +13 more
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Differential expression of preproenkephalin and preprodynorphin mRNAs in striatal neurons: high levels of preproenkephalin expression depend on cerebral cortical afferents [PDF]
The Journal of Neuroscience, 1988 Preproenkephalin and preprodynorphin mRNAs can be detected by in situ hybridization in medium-sized striatal neurons in normal rats and in rats with unilateral cerebral cortical lesions. Hybridization of 35S- labeled oligonucleotide cDNAs complementary to specific regions of each mRNA reveals that preproenkephalin-expressing neurons are more numerous ...
G R, Uhl, B, Navia, J, Douglas
openaire +2 more sources
Implanted Reuptake-deficient or Wild-type Dopaminergic Neurons Improve ON L-dopa Dyskinesias Without OFF-dyskinesias in a Rat Model of Parkinson's Disease [PDF]
, 2012 OFF-L-dopa dyskinesias have been a surprising side-effect of intrastriatal foetal ventral mesencephalic transplantation in patients with Parkinson's disease.
Caron, M. G. +7 more
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Neurobiology of Disease, 2003 Compensatory mechanisms delay the appearance of parkinsonian symptoms. However, both the order of appearance and potential interactions of compensatory mechanisms acting within the nigrostriatal pathway as well as inside and outside the basal ganglia are
Wassilios Meissner +4 more
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Using the Gene Ontology to Annotate Biomedical Journal Articles [PDF]
, 2009 We are creating a gold-standard corpus of manually annotated full-text biomedical journal articles toward natural-language-processing applications. Central to this is our use of entire ontologies of the Open Biomedical Ontologies initiative as well as ...
Lawrence Hunter, Michael Bada
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Transcriptome markers of viral persistence in naturally-infected andes virus (bunyaviridae) seropositive long-tailed pygmy rice rats. [PDF]
PLoS ONE, 2015 Long-tailed pygmy rice rats (Oligoryzomys longicaudatus) are principal reservoir hosts of Andes virus (ANDV) (Bunyaviridae), which causes most hantavirus cardiopulmonary syndrome cases in the Americas.
Corey L Campbell +3 more
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Unilateral ibotenic acid lesions of the prefrontal cortex reduce rotational behavior in 6-hydroxydopamine-lesioned rats [PDF]
, 2006 Rats with 6-hydroxydopamine (6-OHDA)-induced lesions of the substantia nigra are used as a model of Parkinson’s disease (PD), and these “lesioned” rats exhibit a rotational behavior when further injected with apomorphine (APO).
Gonzalez, Daniel +5 more
core +1 more source