Results 31 to 40 of about 2,309 (192)

Transcriptome markers of viral persistence in naturally-infected andes virus (bunyaviridae) seropositive long-tailed pygmy rice rats. [PDF]

PLoS ONE, 2015
Long-tailed pygmy rice rats (Oligoryzomys longicaudatus) are principal reservoir hosts of Andes virus (ANDV) (Bunyaviridae), which causes most hantavirus cardiopulmonary syndrome cases in the Americas.
Corey L Campbell, Fernando Torres-Perez, Mariana Acuna-Retamar, Tony Schountz   +3 more
doaj   +1 more source

Preproenkephalin messenger RNA—containing neurons in striatum of patients with symptomatic and presymptomatic huntington's disease: An in situ hybridization study [PDF]

, 1991
Previous studies have revealed a loss of enkephalin immunoreactivity in the terminals of striatal neurons projecting to the external globus pallidus in patients with early grades of Huntington's disease (HD).
Young, Anne B., Qin, Ying, Albin, Roger L., Penney, John B., Chesselet, Marie-Francoise   +4 more
core   +1 more source

Spatial distribution of D1R- and D2R-expressing medium-sized spiny neurons differs along the rostro-caudal axis of the mouse dorsal striatum

Frontiers in Neural Circuits, 2013
The striatum projection neurons are striatonigral and striatopallidal medium sized-spiny neurons (MSNs) that preferentially express D1 (D1R) and D2 (D2R) dopamine receptors, respectively.
Giuseppe eGangarossa, Giuseppe eGangarossa, Giuseppe eGangarossa, Julie eEspallergues, Julie eEspallergues, Julie eEspallergues, Philippe eMailly, Philippe eMailly, Philippe eMailly, Dimitri eDe Bundel, Dimitri eDe Bundel, Dimitri eDe Bundel, Alban eDe Kerchove D'Exaerde, Denis eHervé, Denis eHervé, Denis eHervé, Jean-Antoine eGirault, Jean-Antoine eGirault, Jean-Antoine eGirault, Emmanuel eValjent, Emmanuel eValjent, Emmanuel eValjent, Patrik eKrieger   +22 more
doaj   +1 more source

Targeted Cell Reprogramming Produces Analgesic Chromaffin-Like Cells from Human Mesenchymal Stem Cells

Cell Transplantation, 2013
Transplantation of allogeneic adrenal chromaffin cells demonstrated the promise of favorable outcomes for pain relief in patients. However, there is a very limited availability of suitable human adrenal gland tissues, genetically well-matched donors in ...
T. Qu M.D., Ph.D., G. Shi, K. Ma, H. N. Yang, W. M. Duan, G. D. Pappas   +5 more
doaj   +1 more source

Upregulation of Striatal Preproenkephalin Gene Expression Occurs before the Appearance of Parkinsonian Signs in 1-Methyl-4-phenyl- 1,2,3,6-tetrahydropyridine Monkeys

Neurobiology of Disease, 2001
GABA and enkephalin-utilizing efferents from the striatum to the external segment of the pallidal complex (GPe) are thought to be overactive in Parkinson's disease (PD).
Erwan Bezard, Paula Ravenscroft, Christian E. Gross, Alan R. Crossman, Jonathan M. Brotchie   +4 more
doaj   +1 more source

Reward associated with singing behavior correlates with opioid-related gene expression in the medial preoptic nucleus in male European starlings. [PDF]

PLoS ONE, 2014
Birdsong consists of species-specific learned vocal sequences that are used primarily to attract mates and to repel competitors during the breeding season.
Lauren V Riters, Sharon A Stevenson, M Susan DeVries, Melissa A Cordes   +3 more
doaj   +1 more source

Enhanced Preproenkephalin-B-Derived Opioid Transmission in Striatum and Subthalamic Nucleus Converges Upon Globus Pallidus Internalis in L-3,4-dihydroxyphenylalanine-Induced Dyskinesia

, 2007
Background: A role for enhanced opioid peptide transmission has been suggested in the genesis of levodopa-induced dyskinesia. However, basal ganglia nuclei other than the striatum have not been regarded as potential sources, and the opioid precursors ...
Dovero, Sandra, Crossman, Alan R., Aubert, Incarnation, Bioulac, Bernard H., Guigoni, Céline, Bloch, Bertrand, Li, Qin, Bezard, Erwan, Gross, Christian E.   +8 more
core   +1 more source

Localization of preproenkephalin mRNA-expressing cells in rat auditory brainstem with in situ hybridization [PDF]

, 1993
Hair cells and auditory nerve dendrites in the inner ear are innervated by pontine neurons that have been demonstrated by immunochemical techniques to contain several neurotransmitters, including acetylcholine and the opioid peptide enkephalins and ...
Landry, Douglas R., Altschuler, Richard A., Hoffman, Douglas W., Hochreiter, Jill S., Treadwell, Melinda D., Brimijoin, Megan R., Gardner, Paul D.   +6 more
core   +1 more source

Anxiety- and depressive-like responses and c-fos activity in preproenkephalin klockout mice: Oversensitivity hypothesis of enkephalin deficit-induced posttraumatic stress disorder

Journal of Biomedical Science, 2010
The present study used the preproenkephalin knockout (ppENK) mice to test whether the endogenous enkephalins deficit could facilitate the anxiety- and depressive-like symptoms of posttraumatic stress disorder (PTSD).
Shyu Bai-Chuang, Chen Tsung-Chieh, Kung Jen-Chuang, Hsiao Sigmund, Huang Andrew   +4 more
doaj   +1 more source

Cholestasis is associated with preproenkephalin mRNA expression in the adult rat liver

, 1995
Cholestatic liver disease is associated with clinical and experimental findings consistent with increased opioidergic neuromodulation, increased plasma total opioid activity, and elevated plasma enkephalin concentrations. In contrast to the normal adult
S. L. Sabol, W. S. Young, N. V. Bergasa, D. E. Kleiner, E. A. Jones   +4 more
core   +1 more source