Molecular Brain, 2020 Clathrin-mediated endocytosis plays an important role in the recycling of synaptic vesicle in presynaptic terminals, and in the recycling of transmitter receptors in neuronal soma/dendrites.
Jung-Hwa Tao-Cheng
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Synapsin selectively controls the mobility of resting pool vesicles at hippocampal terminals [PDF]
, 2012 Presynaptic terminals are specialized sites for information transmission where vesicles fuse with the plasma membrane and are locally recycled. Recent work has extended this classical view, with the observation that a subset of functional vesicles is ...
Burden, Jemima J +8 more
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Effects of subthalamic nucleus lesions and stimulation upon corticostriatal afferents in the 6-hydroxydopamine-lesioned rat. [PDF]
PLoS ONE, 2012 Abnormalities of striatal glutamate neurotransmission may play a role in the pathophysiology of Parkinson's disease and may respond to neurosurgical interventions, specifically stimulation or lesioning of the subthalamic nucleus (STN).
Ruth H Walker +5 more
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Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses [PDF]
, 2006 Synaptic vesicle (SV) exocytosis mediating neurotransmitter release occurs spontaneously at low intraterminal calcium concentrations and is stimulated by a rise in intracellular calcium.
A. Scheuber +32 more
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Calcium-independent inhibitory G-protein signaling induces persistent presynaptic muting of hippocampal synapses [PDF]
, 2011 Adaptive forms of synaptic plasticity that reduce excitatory synaptic transmission in response to prolonged increases in neuronal activity may prevent runaway positive feedback in neuronal circuits.
Chang, Chun Yun +3 more
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Tetrodotoxin‐resistant electric activity in presynaptic terminals [PDF]
The Journal of Physiology, 1969 1. The electric properties of the giant synapse in the stellate ganglion of the squid have been further investigated.2. During tetrodotoxin (TTX) paralysis, a local response can be elicited from the terminal parts of the presynaptic axons after intracellular injection of tetraethyl ammonium ions (TEA).3.
B, Katz, R, Miledi
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Rapid Changes in the Translatome during the Conversion of Growth Cones to Synaptic Terminals
Cell Reports, 2016 Summary: A common step in the formation of neural circuits is the conversion of growth cones to presynaptic terminals. Characterizing patterns of global gene expression during this process is problematic due to the cellular diversity of the brain and the
Kelvin Xi Zhang +4 more
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Translational Neurodegeneration, 2022 Background Axonal degeneration and defects in neuromuscular neurotransmission represent a pathological hallmark in spinal muscular atrophy (SMA) and other forms of motoneuron disease.
Chunchu Deng +9 more
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Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice [PDF]
, 2014 Acid-sensing ion channels (ASIC) open in response to extracellular acidosis. ASIC1a, a particular subtype of these channels, has been described to have a postsynaptic distribution in the brain, being involved not only in ischemia and epilepsy, but also ...
Colettis, Natalia Claudia +8 more
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Glutamate-Dependent Stabilization of Presynaptic Terminals [PDF]
Neuron, 2003 Dissecting the mechanisms underlying synapse formation and elimination is fundamental to understand how the nervous system is constructed and subsequently modified. Two studies by Tashiro et al. and by Hashimoto and Kano in this issue of Neuron provide new insights into the roles of neurotransmitter glutamate release in regulating the motility of ...
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