Results 11 to 20 of about 51,824 (254)

Strength and precision of neurotransmission at mammalian presynaptic terminals. [PDF]

open access: yesProc Jpn Acad Ser B Phys Biol Sci, 2015
Classically, the basic concept of chemical synaptic transmission was established at the frog neuromuscular junction, and direct intracellular recordings from presynaptic terminals at the squid giant presynaptic terminal have further clarified principles of neurotransmitter release.
Takahashi T.
europepmc   +4 more sources

Investigate Synaptic Vesicles Mobility in Neuronal Culture Axons by FRAP Imaging

open access: yesBio-Protocol, 2021
Synaptic vesicles (SVs) are clustered in the presynaptic terminals and consistently trafficking along axons. Based on their release features, SVs are classified into different “pools”.
Xiao Min Zhang   +2 more
doaj   +1 more source

Developmental up-regulation of vesicular glutamate transporter-1 promotes neocortical presynaptic terminal development. [PDF]

open access: yesPLoS ONE, 2012
Presynaptic terminal formation is a complex process that requires assembly of proteins responsible for synaptic transmission at sites of axo-dendritic contact.
Corbett T Berry   +3 more
doaj   +1 more source

Editorial: Molecular Nanomachines of the Presynaptic Terminal [PDF]

open access: yesFrontiers in Synaptic Neuroscience, 2016
Cell biology and neurobiology have started many decades ago as attempts to unravel the complexity of cellular processes, by studying different elements, from membranes and organelles to molecules in isolation. Through ever increasing technological improvements, a huge amount of information has accumulated on the molecular organization of the cell, and ...
Rizzoli, Silvio O., Tabares, Lucía
openaire   +5 more sources

Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses

open access: yesBiomolecules, 2022
Synaptic transmission is essential for controlling motor functions and maintaining brain functions such as walking, breathing, cognition, learning, and memory.
Kenji Takikawa, Hiroshi Nishimune
doaj   +1 more source

Excitement about Inhibitory Presynaptic Terminals [PDF]

open access: yesNeuron, 2015
Based on extrapolation from excitatory synapses, it is often assumed that depletion of the releasable pool of synaptic vesicles is the main factor underlying depression at inhibitory synapses. In this issue of Neuron, using subcellular patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba (2015) show that at Purkinje cell ...
David H.F. Vandael   +2 more
openaire   +2 more sources

Neurexin mediates the assembly of presynaptic terminals [PDF]

open access: yesNature Neuroscience, 2003
Neurexins are a large family of proteins that act as neuronal cell-surface receptors. The function and localization of the various neurexins, however, have not yet been clarified. Beta-neurexins are candidate receptors for neuroligin-1, a postsynaptic membrane protein that can trigger synapse formation at axon contacts.
Dean, Camin   +6 more
openaire   +3 more sources

Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain

open access: yeseLife, 2016
Communication between pre- and postsynaptic cells promotes the initial organization of synaptic specializations, but subsequent synaptic stabilization requires transcriptional regulation.
Akiko Terauchi   +4 more
doaj   +1 more source

Axonal α7* nicotinic acetylcholine receptors modulate glutamatergic signaling and synaptic vesicle organization in ventral hippocampal projections

open access: yesFrontiers in Neural Circuits, 2022
Modulation of the release of glutamate by activation of presynaptic nicotinic acetylcholine receptors (nAChRs) is one of the most prevalent mechanism of nicotinic facilitation of glutamatergic transmission in cortico-limbic circuits.
Chongbo Zhong   +3 more
doaj   +1 more source

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