Results 11 to 20 of about 51,824 (254)
Strength and precision of neurotransmission at mammalian presynaptic terminals. [PDF]
Classically, the basic concept of chemical synaptic transmission was established at the frog neuromuscular junction, and direct intracellular recordings from presynaptic terminals at the squid giant presynaptic terminal have further clarified principles of neurotransmitter release.
Takahashi T.
europepmc +4 more sources
Investigate Synaptic Vesicles Mobility in Neuronal Culture Axons by FRAP Imaging
Synaptic vesicles (SVs) are clustered in the presynaptic terminals and consistently trafficking along axons. Based on their release features, SVs are classified into different “pools”.
Xiao Min Zhang +2 more
doaj +1 more source
Developmental up-regulation of vesicular glutamate transporter-1 promotes neocortical presynaptic terminal development. [PDF]
Presynaptic terminal formation is a complex process that requires assembly of proteins responsible for synaptic transmission at sites of axo-dendritic contact.
Corbett T Berry +3 more
doaj +1 more source
Editorial: Molecular Nanomachines of the Presynaptic Terminal [PDF]
Cell biology and neurobiology have started many decades ago as attempts to unravel the complexity of cellular processes, by studying different elements, from membranes and organelles to molecules in isolation. Through ever increasing technological improvements, a huge amount of information has accumulated on the molecular organization of the cell, and ...
Rizzoli, Silvio O., Tabares, Lucía
openaire +5 more sources
Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses
Synaptic transmission is essential for controlling motor functions and maintaining brain functions such as walking, breathing, cognition, learning, and memory.
Kenji Takikawa, Hiroshi Nishimune
doaj +1 more source
Central Presynaptic Terminals Are Enriched in ATP but the Majority Lack Mitochondria [PDF]
Vrushali Chavan +2 more
exaly +2 more sources
Excitement about Inhibitory Presynaptic Terminals [PDF]
Based on extrapolation from excitatory synapses, it is often assumed that depletion of the releasable pool of synaptic vesicles is the main factor underlying depression at inhibitory synapses. In this issue of Neuron, using subcellular patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba (2015) show that at Purkinje cell ...
David H.F. Vandael +2 more
openaire +2 more sources
Neurexin mediates the assembly of presynaptic terminals [PDF]
Neurexins are a large family of proteins that act as neuronal cell-surface receptors. The function and localization of the various neurexins, however, have not yet been clarified. Beta-neurexins are candidate receptors for neuroligin-1, a postsynaptic membrane protein that can trigger synapse formation at axon contacts.
Dean, Camin +6 more
openaire +3 more sources
Communication between pre- and postsynaptic cells promotes the initial organization of synaptic specializations, but subsequent synaptic stabilization requires transcriptional regulation.
Akiko Terauchi +4 more
doaj +1 more source
Modulation of the release of glutamate by activation of presynaptic nicotinic acetylcholine receptors (nAChRs) is one of the most prevalent mechanism of nicotinic facilitation of glutamatergic transmission in cortico-limbic circuits.
Chongbo Zhong +3 more
doaj +1 more source

