Results 81 to 90 of about 51,824 (254)

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

Advanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh, Ki‐bum Lee, Junghyeon Lee, Seunghee Cho, Malkeshkumar Patel, Hangfei Li, Yu Wen, Ye Zhou, Joondong Kim   +8 more
wiley   +1 more source

Homocysteine aggravates ROS-induced depression of transmitter release from motor nerve terminals: potential mechanism of peripheral impairment in motor neuron diseases associated with hyperhomocysteinemia

Frontiers in Cellular Neuroscience, 2015
Homocysteine (HCY) is a pro-inflammatory sulphur-containing redox active endogenous amino acid, which concentration increases in neurodegenerative disorders including amyotrophic lateral sclerosis (ALS).
Ellya eBukharaeva, Ellya eBukharaeva, Anastasia eShakirzyanova, Anastasia eShakirzyanova, Venera eKhuzakhmetova, Guzel eSitdikova, Rashid eGiniatullin, Rashid eGiniatullin   +7 more
doaj   +1 more source

Electromagnetic Radiation Stimulated Learning in Perovskite Nickelates

Advanced Science, EarlyView.
ABSTRACT Biological plasticity refers to the ability of synapses to strengthen or weaken over time. These adaptive properties play a fundamental role in learning and memory, spanning many orders of magnitude in timescales. Short‐term plasticity (STP) arises from rapid correlative activity, while long‐term plasticity (LTP) is governed by slower ...
Ranjan Kumar Patel, Kabir Zama, Matthew Smart, Ramya Eathirajan, Ivan Seskar, Narayan Mandayam, Guangxin Ni, Martin Mönnigmann, Shriram Ramanathan   +8 more
wiley   +1 more source

Presynaptic Glycine Receptors Increase GABAergic Neurotransmission in Rat Periaqueductal Gray Neurons

Neural Plasticity, 2013
The periaqueductal gray (PAG) is involved in the central regulation of nociceptive transmission by affecting the descending inhibitory pathway. In the present study, we have addressed the functional role of presynaptic glycine receptors in spontaneous ...
Kwi-Hyung Choi, Michiko Nakamura, Il-Sung Jang   +2 more
doaj   +1 more source

Activity-regulated cytoskeletal-associated protein (Arc) in presynaptic terminals and extracellular vesicles in hippocampal synapses. [PDF]

Front Mol Neurosci, 2023
Ringsevjen H, Egbenya DL, Bieler M, Davanger S, Hussain S.   +4 more
europepmc   +1 more source

Thermally Stable Organic Synaptic Transistors Using a High‐Tg Polymer Electret

Advanced Intelligent Systems, EarlyView.
A high–glass‐transition‐temperature cyclic olefin copolymer (COC) electret enables thermally stable organic synaptic transistors for neuromorphic operation in harsh environments. UV–ozone treatment increases the trap density in COC, providing robust multilevel conductance and key synaptic functions (excitatory postsynaptic current/ inhibitory ...
Hoyoung Cho, Bombi Kim, Kyoungeun Lee, Moohyun Kim, Chaegwang Lim, Yeyun Bae, Jaeyeop Lee, Jiyoon Oh, Hyeok Kim, Jeongkyun Roh   +9 more
wiley   +1 more source

Mouse-derived Synaptosomes Trypsin Cleavage Assay to Characterize Synaptic Protein Sub-localization

Bio-Protocol
Neurons communicate through neurotransmission at highly specialized junctions called synapses. Each neuron forms numerous synaptic connections, consisting of presynaptic and postsynaptic terminals.
Jasmeet Shergill, Domenico Azarnia Tehran   +1 more
doaj   +1 more source

Nanoscale organization of Ca_V2.1 splice isoforms at presynaptic terminals: implications for synaptic vesicle release and synaptic facilitation. [PDF]

Biol Chem, 2023
Cingolani LA, Thalhammer A, Jaudon F, Muià J, Baj G.   +4 more
europepmc   +1 more source

Refining Domain‐Based Prognostication in DNM1 Encephalopathy: A Mild Phenotype Associated With a GTPase Domain Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT DNM1 encephalopathy is a rare autosomal dominant genetic condition characterized by a range of neurological and developmental manifestations. The typical phenotype is severe, including profound intellectual disability, treatment‐resistant epilepsy, ataxia, and structural brain abnormalities. However, milder presentations have increasingly been
Caroline Crain, Hope Northrup, Laura S. Farach, Sureni V. Mullegama, Kathleen Shields, Gretchen Von Allmen, Kate Richardson   +6 more
wiley   +1 more source

Soma-localized Rab39 inhibits synaptic autophagy by controlling trafficking of Atg9 vesicles

The EMBO Journal
Presynaptic terminals can be located far from the neuronal cell body and are thought to independently regulate protein and organelle turnover. Autophagy is a critical process for maintaining proteostasis, and its synaptic dysregulation is associated with
Ayse Kilic, Gokhan Ozturan, Dirk Vandekerkhove, Sabine Kuenen, Jef Swerts, Esther Muñoz Pedrazo, Carles Calatayud Aristoy, Abril Escamilla Ayala, Nikky Corthout, Pablo Hernández Varas, Stéphane Plaisance, Valerie Uytterhoeven, Eliana Nachman, Patrik Verstreken   +13 more
doaj   +1 more source