Results 51 to 60 of about 18,376 (235)

Human Infections with Plasmodium knowlesi, the Philippines. [PDF]

open access: yes, 2008
Five human cases of infection with the simian malaria parasite Plasmodium knowlesi from Palawan, the Philippines, were confirmed by nested PCR. This study suggests that this zoonotic infection is found across a relatively wide area in Palawan and ...
Bell, David   +9 more
core   +3 more sources

The impact of using primaquine without prior G6PD testing: a case series describing the obstacles to the medical management of haemolysis [version 2; peer review: 2 approved]

open access: yesWellcome Open Research, 2019
Radical cure of Plasmodium vivax malaria in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals employs weekly primaquine dosing. This is the only recommended regimen for this patient sub-group.
Cindy S. Chu   +5 more
doaj   +1 more source

Simplified and Rapid Determination of Primaquine and 5,6-Orthoquinone Primaquine by UHPLC-MS/MS: Its Application to a Pharmacokinetic Study

open access: yesMolecules, 2021
The method for the determination of primaquine (PQ) and 5,6-orthoquinone primaquine (5,6-PQ), the representative marker for PQ active metabolites, via CYP2D6 in human plasma and urine has been validated.
Waritda Pookmanee   +5 more
doaj   +1 more source

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

open access: yes, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew   +5 more
core   +1 more source

Relapse of imported Plasmodium vivax malaria is related to primaquine dose: a retrospective study

open access: yesMalaria Journal, 2012
Background Relapsing Plasmodium vivax infection results in significant morbidity for the individual and is a key factor in transmission. Primaquine remains the only licensed drug for prevention of relapse.
Townell Nicola   +3 more
doaj   +1 more source

Are transnational tobacco companies' market access strategies linked to economic development models? A case study of South Korea. [PDF]

open access: yes, 2013
Transnational tobacco companies (TTCs) have used varied strategies to access previously closed markets. Using TTCs' efforts to enter the South Korean market from the late 1980s as a case study, this article asks whether there are common patterns in these
Amon, A   +21 more
core   +6 more sources

Levels of primaquine and carboxyprimaquine in patients with malaria vivax from the Brazilian Amazon basin

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2018
In the last two years, a substantial increase in the number of malaria vivax cases has occurred in the Brazilian Amazon basin. The adequate exposure of hypnozoites to primaquine is a matter of interest as these dormant forms are responsible for the ...
Amanda Gabryelle Nunes Cardoso Mello   +7 more
doaj   +1 more source

Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination

open access: yes, 2015
Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting.
Eckhoff, Philip   +2 more
core   +1 more source

Taking Drugs to Help Others [PDF]

open access: yes, 2016
Every day the news shows us provoking stories about what's going on in the world, about events which raise moral questions and problems. In Philosophers Take On the World a team of philosophers get to grips with a variety of these controversial issues ...
Douglas, Thomas
core  

Costs Associated with Malaria in Pregnancy in the Brazilian Amazon, a Low Endemic Area Where Plasmodium vivax Predominates. [PDF]

open access: yes, 2016
BACKGROUND: Information on costs associated with malaria in pregnancy (MiP) in low transmission areas where Plasmodium vivax predominates is so far missing. This study estimates health system and patient costs of MiP in the Brazilian Amazon.
Bardají, A   +7 more
core   +4 more sources

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