Results 71 to 80 of about 16,193 (191)
Blood Parasites and Wildlife: The Development of a Discipline
Changes in our knowledge on blood parasite infections of wild animals in the last 30 years is reviewed with emphasis on taxonomy and phylogeny, impact of infections on fitness, and distribution of blood parasites. ABSTRACT In the last 30 years, the area of the study of parasitism caused by blood parasite infections on wildlife has suffered an ...
Santiago Merino
wiley +1 more source
Bioequivalence of a new coated 15 mg primaquine formulation for malaria elimination
Background With only one 15 mg primaquine tablet registered by a stringent regulatory authority and marketed, more quality-assured primaquine is needed to meet the demands of malaria elimination.
Julie Nguyen Ngoc Pouplin +11 more
doaj +1 more source
Low-dose primaquine for falciparum malaria [PDF]
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Bousema, Teun +3 more
core +1 more source
ABSTRACT Background The implementation of pharmacogenetics in clinical practice increasingly relies on multigene panels. Objectives The objective of this study is to develop harmonized recommendations for the design and analytical implementation of multigene pharmacogenetic panels, defining clinically relevant genes and associated regions of interest ...
Nicolas Picard +29 more
wiley +1 more source
Primaquine and Chloroquine Fumardiamides as Promising Antiplasmodial Agents
This paper describes a continuation of our efforts in the pursuit of novel antiplasmodial agents with optimized properties. Following our previous discovery of biologically potent asymmetric primaquine (PQ) and halogenaniline fumardiamides (1−6 ...
Maja Beus +7 more
doaj +1 more source
The enantiomeric resolution of primaquine, quinacrine and tafenoquine antibacterial medicines is described on Chirobiotc R column (150 ×4.6 mm, 5.0 µm). Two eluents used were methanol–acetonitrile-water-triethyl amine in the ratio of 70:10:20:0.1 (I) and
Zeid A. ALOthman +2 more
doaj +1 more source
PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity [PDF]
Primacenes, novel ferrocene-primaquine conjugates, were synthesized and screened for their antimalarial and anti-pneumocystis activity. Primacenes obtained by coupling primaquine amino acid derivatives to ferrocenoic acid were significantly active ...
Jiri Gut +7 more
core +1 more source
Malaria polymerase chain reaction (PCR) testing is more sensitive than conventional diagnostics. Routine PCR screening of at‐risk asymptomatic hematopoietic cell donors and transplant candidates may prevent unnecessary deferrals or treatment. In our experience, PCR negativity during screening or after treatment supports donor/candidate eligibility ...
Mary M. Czech +5 more
wiley +1 more source
BackgroundPrimaquine is the only licensed drug for eradicating Plasmodium vivax hypnozoites and, therefore, preventing relapses of vivax malaria. It is a vital component of global malaria elimination efforts.
Nicholas M Douglas +9 more
doaj +1 more source
Factors affecting primaquine combination treatment in Malaria patients in Selangor, Malaysia
Introduction: Primaquine is vital for the management of liver-stage Plasmodium vivax and Plasmodium ovale malaria. However, primaquine effectiveness is dependent on various factors and differs between populations.
Norliza Mat Ariffin +4 more
doaj +1 more source

