Results 151 to 160 of about 37,275 (255)

Timing and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi, Filip Gnesin, Baker Nawfal Jawad, Zia Niazi, Puriya Daniel Wuertz Yazdanfard, Anne P. Toft‐Petersen, Kathrine Kold Sørensen, Amani Meaidi, Yousif Subhi, Christian Torp‐Pedersen   +9 more
wiley   +1 more source

Foxn3 is part of a transcriptional network that regulates primary cilia in the developing retina. [PDF]

Development
Zhang H, Nair T, Meng F, Turner DL.
europepmc   +1 more source

A prospective randomised comparison of two different stenting sutures when using the Baerveldt 101–350 aqueous shunt – Lab transition to clinical process

Acta Ophthalmologica, EarlyView.
Abstract Purpose The Baerveldt glaucoma drainage implant (BGI 101–350) is one of the most effective treatment options for managing refractory glaucoma. To mitigate early hypotony in non‐valved implants, intraluminal occluding sutures (IOSs) are commonly used.
Evripidis Sykakis, Anastasia Tsiogka, Vasileios Selimis, Minas I. Aslanides, Athanasios Skouras, George Kenanakis, Ioannis M. Aslanides, Minas M. Stylianakis   +7 more
wiley   +1 more source

Primary cilia and BBS4 are required for postnatal pituitary development. [PDF]

Dev Biol
Brewer KM, Brewer KK, Richardson NC, Reiter JF, Berbari NF, Konjikusic MJ.   +5 more
europepmc   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for ependymomas

Brain Pathology, EarlyView.
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Laveniya Satgunaseelan, Michael E. Buckland, Geeta Chacko, Kenta Masui, Junji Shibahara, Vani Santosh, Maysa Al‐Hussaini, Sung‐Hye Park, Tarik Tihan, Ho‐Keung Ng, Pieter Wesseling, David N. Louis, Chitra Sarkar, Takashi Komori   +13 more
wiley   +1 more source

Primary cilia function as hubs for signal transduction. [PDF]

Cell Biosci
Li B, He YY, Yang ZM.
europepmc   +1 more source

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

Brain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova, Ondrej Bernatik, Katarina Cimborova, Martin Barak, Michal Hendrych, Karolina Kocourkova, Marie Sulcova, Jaroslav Olha, Katerina Amruz Cerna, Zdenek Hodny, Radim Jancalek, Dasa Bohaciakova   +11 more
wiley   +1 more source

Atrial Fibrillation and Primary Cilia-Associated Genes: The Role of CEP68. [PDF]

Int J Mol Sci
Dong Z, Al-Shama RFM, van den Berg NWE, Kawasaki M, Terpstra MM, Arrarte Terreros N, Hulsman EL, Jongejan A, Arora RA, van Boven WJP, Driessen AHG, Bezzina CR, Jurgens SJ, de Groot JR.   +13 more
europepmc   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

British Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source