Results 171 to 180 of about 37,275 (255)

A Ciliary Phosphoinositide Pathway Regulates the Dosage of Polycystins in Primary Cilia. [PDF]

open access: yesJ Am Soc Nephrol
Chen C   +18 more
europepmc   +1 more source

Antipredatory Strategies of Anurans: An Updated Conceptual Review

open access: yesEthology, EarlyView.
To unravel the evolutionary dynamics of predator–prey interactions, we propose an updated, three‐tiered classification of anuran antipredatory strategies. By mapping non‐behavioral, individual, and group defenses across five functional phases, this integrative framework introduces the concept of synergetic coupling.
Ubiratã Ferreira Souza   +3 more
wiley   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

open access: yesThe FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez   +7 more
wiley   +1 more source

Primary cilia.

open access: yesJournal of musculoskeletal & neuronal interactions, 2008
openaire   +1 more source

PML as a neuroprotective guardian: Leveraging nuclear protein quality control to mitigate neurotoxicity of an ALS‐associated NEK1 variant

open access: yesThe FEBS Journal, EarlyView.
Insoluble protein aggregates are a hallmark of neurodegenerative diseases like amyotrophic lateral sclerosis (ALS). The ubiquitin–proteasome system (UPS) serves as a neuroprotective quality control mechanism that clears aggregates. PML nuclear bodies (NBs) were proposed to serve as hubs for SUMO‐primed ubiquitylation and degradation of misfolded ...
Tabea Stark, Stefan Müller
wiley   +1 more source

Diagnosing primary ciliary dyskinesia in Australian adults: 10 years of testing

open access: yesInternal Medicine Journal, EarlyView.
Abstract Primary ciliary dyskinesia (PCD) is a rare inherited disorder characterised by impaired ciliary function, leading to chronic upper and lower airway disease from early life. Limited awareness of the condition contributes to delayed diagnosis, with some individuals first diagnosed in adulthood following specialised testing. We describe 91 adults
P. J. Robinson
wiley   +1 more source

ALIX and ITCH localize to the base of primary cilia and negatively regulate ciliary Polycystin-2 levels. [PDF]

open access: yesBMC Mol Cell Biol
Berggreen CR   +14 more
europepmc   +1 more source

First Record of Arrhenophagus chionaspidis Aurivillius (Hymenoptera: Encyrtidae) Parasitizing White Mango Scale in Kenya: Its Potential Distribution and Prospects in Biocontrol

open access: yesJournal of Applied Entomology, EarlyView.
ABSTRACT The white mango scale, Aulacaspis tubercularis Newstead (Hemiptera: Diaspididae), is one of the most destructive pests of mango worldwide. Its current management in most of the invaded areas largely depends on the intensive use of chemical insecticides.
Francis Obala   +7 more
wiley   +1 more source

Cholangiocytes' primary cilia regulate DNA damage response and repair. [PDF]

open access: yesAm J Physiol Gastrointest Liver Physiol
Peixoto E   +6 more
europepmc   +1 more source

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