Results 161 to 170 of about 37,275 (255)

Compartmentalized Nutrient and Hormone Sensing in β-Cells: the Role of Primary Cilia. [PDF]

Physiology (Bethesda)
Hughes JW, Merrins MJ.
europepmc   +1 more source

Biopsy of Iris and Anterior Chamber Tumours: Fine Needle, Minimally Invasive and Excision Techniques ‐ Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Several benign, inflammatory and malignant lesions can present as iris or anterior chamber masses, including iris naevi, cysts, adenomas, leiomyomas, nodules, vascular tumours, melanomas, metastases, as well as iris and pigment epithelium adenocarcinomas. Fortunately, benign iris lesions are much more common than malignant tumours and many can
Charles N. J. McGhee, Joevy Z. Lim, Peter W. Hadden, Jie Zhang   +3 more
wiley   +1 more source

Primary Cilia and Cardiovascular Risk Factors in Alzheimer's Disease. [PDF]

Brain Sci
Sunderman CL, Forero KV, Alorjani Q, Buqaileh R, Gallagher GM, Ventresca SM, Messer WS, AbouAlaiwi WA.   +7 more
europepmc   +1 more source

Australian and New Zealand Glaucoma Society (ANZGS) Consensus on Interventional Glaucoma

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Traditional reactive ‘wait and see’ approaches in glaucoma management often result in unacceptable rates of permanent vision loss. This consensus defines a proactive ‘interventional glaucoma’ framework tailored for the Australian and New Zealand healthcare context. Methods A modified Delphi consensus process was utilised, consisting
Graham A. Lee, Lance Liu, Ridia Lim, Rajiv Shah, Robert J. Casson, Keith R. Martin, Helen Danesh‐Meyer, Ashish Agar, Jennifer C. Fan Gaskin, Judy Y. Ku, Geoffrey Chan, Anna Galanopoulos, Shamira Perera   +12 more
wiley   +1 more source

Whole-Mount Visualization of Primary Cilia in the Developing Mouse Brain. [PDF]

Bio Protoc
Gutierrez OT, Liu X, Ge X.
europepmc   +1 more source

Biallelic Truncating Variant in LRGUK Is Associated With Severe Multiple Morphological Abnormalities of the Sperm Flagella and Sperm Nuclear Defects in Humans

Clinical Genetics, EarlyView.
A homozygous truncating variant in LRGUK results in loss of the LRGUK protein and causes multiple morphological abnormalities of the flagella (MMAF), disrupted axonemal architecture, central pair defects, abnormal chromatin organization, and severe male infertility, establishing LRGUK as a novel human infertility gene.
Wiâme Mokkedem, Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Célia Tebbakh, Nicolas Thierry‐Mieg, Marie Bidart, Antonella Migliaccio, Rosanna Chianese, Christophe Arnoult, Raoudha Zouari, Zine‐Eddine Kherraf, Pierre F. Ray, Guillaume Martinez, Charles Coutton   +14 more
wiley   +1 more source

Melanocortin 3 Receptors Do Not Specifically Localize to Primary Cilia in Cultured Human and Rodent Neurons. [PDF]

Cell Biochem Funct
Vos N, Moro A, Hul WV, Kleinendorst L, Florijn RJ, la Fleur SE, Verhage M, van Haelst MM, Toonen RF.   +8 more
europepmc   +1 more source

A Novel Device to Improve the Tolerability of Intranasal Corticosteroid Sprays for Allergic Rhinitis and Postoperative Chronic Rhinosinusitis: A Crossover Trial

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Allergic rhinitis (AR) and chronic rhinosinusitis (CRS) are commonly treated with intranasal corticosteroid sprays. Despite their efficacy, unpleasant sensations associated with their application, including post‐nasal drip and nasal irritation, are often cited as reasons for poor compliance.
Sethmi Ranasinghe, Xenia Berger, Wandia Kimita, Kristi Biswas, Raymond Kim, Richard Douglas   +5 more
wiley   +1 more source

Primary cilia gene defects in BMSCs induce idiopathic scoliosis. [PDF]

Cell Mol Life Sci
Zhang L, Yang W, Zhao Z, Wang Y, Wang H, Zhao N, Zhou J, Song Z, Zhang Z, Li T, Zhe S, Qian G, Liu Y, Xie J.   +13 more
europepmc   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source