Results 11 to 20 of about 78,237 (351)
Primary Cilia and Atherosclerosis [PDF]
Frontiers in Physiology, 2021 In artery tree, endothelial function correlates with the distribution of shear stress, a dragging force generated by flowing blood. In laminar shear stress areas, endothelial cells (ECs) are available to prevent atherosclerosis, however, ECs in disturbed shear stress sites are featured with proinflammation and atherogenesis.
Zhi-Mei Wang +3 more
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Calprotectin: An Ignored Biomarker of Neutrophilia in Pediatric Respiratory Diseases
Children, 2021 Calprotectin (CP) is a non-covalent heterodimer formed by the subunits S100A8 (A8) and S100A9 (A9). When neutrophils become activated, undergo disruption, or die, this abundant cytosolic neutrophil protein is released.
Grigorios Chatziparasidis, Ahmad Kantar
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Effects of Sesquiterpene Lactones on Primary Cilia Formation (Ciliogenesis)
Toxins, 2023 Sesquiterpene lactones (SLs), plant-derived metabolites with broad spectra of biological effects, including anti-tumor and anti-inflammatory, hold promise for drug development.
Marina Murillo-Pineda +9 more
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Current Osteoporosis Reports, 2023 Abstract Purpose of Review The purpose of this review is to provide a background on osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing. Recent Findings Osteocytes are thought to be the primary mechanosensing cells in bone tissue ...
Verbruggen, S.W. +2 more
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Fluorescence imaging of beta cell primary cilia
Frontiers in Endocrinology, 2022 Primary cilia are slender cell-surface organelles that project into the intercellular space. In pancreatic beta cells, primary cilia coordinate a variety of cell responses including GPCR signaling, calcium influx, and insulin secretion, along with likely
Zipeng A. Li +3 more
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Vaping in Asthmatic Adolescents: Time to Deal with the Elephant in the Room
Children, 2022 Adolescence is a period characterized by developmental, psychological, and psychosocial alterations, with a major impact on youths’ attitudes and perceptions.
Grigorios Chatziparasidis, Ahmad Kantar
doaj +1 more source
Assembly of primary cilia [PDF]
Developmental Dynamics, 2008 AbstractPrimary cilia are microtubule‐based, hair‐like sensory organelles present on the surface of most growth‐arrested cells in our body. Recent research has demonstrated a crucial role for primary cilia in regulating vertebrate developmental pathways and tissue homeostasis, and defects in genes involved in primary cilia assembly or function have ...
Pedersen, Lotte B +3 more
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Recent advances in primary cilia in bone metabolism
Frontiers in Endocrinology, 2023 Primary cilia are microtubule-based organelles that are widespread on the cell surface and play a key role in tissue development and homeostasis by sensing and transducing various signaling pathways.
Fenfen Lian +4 more
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Visualizing renal primary cilia [PDF]
Nephrology, 2013 AbstractRenal primary cilia are microscopic sensory organelles found on the apical surface of epithelial cells of the nephron and collecting duct. They are based upon a microtubular cytoskeleton, bounded by a specialized membrane, and contain an array of proteins that facilitate their assembly, maintenance and function.
Deane, James +7 more
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Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults
Molecular Brain, 2020 Primary cilia are centriole-derived sensory organelles that are present in most mammalian cells, including astrocytes and neurons. Evidence is emerging that astrocyte and neuronal primary cilia demonstrate a dichotomy in the mature mouse brain.
Ashley Sterpka +5 more
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