Results 21 to 30 of about 4,554,367 (185)

Cilia-mediated signalling in the embryonic nodes: A computational fluid-structure-protein interaction (FSPI) model [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Norris, D, Chen, D, Ventikos, Y   +3 more
core   +6 more sources

Osteocytes and Primary Cilia

Current Osteoporosis Reports, 2023
Abstract Purpose of Review The purpose of this review is to provide a background on osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing. Recent Findings Osteocytes are thought to be the primary mechanosensing cells in bone tissue ...
Verbruggen, S.W., Sittichokechaiwut, A., Reilly, G.C.   +2 more
openaire   +4 more sources

Assembly of primary cilia [PDF]

Developmental Dynamics, 2008
AbstractPrimary cilia are microtubule‐based, hair‐like sensory organelles present on the surface of most growth‐arrested cells in our body. Recent research has demonstrated a crucial role for primary cilia in regulating vertebrate developmental pathways and tissue homeostasis, and defects in genes involved in primary cilia assembly or function have ...
Pedersen, Lotte B, Veland, Iben R, Schrøder, Jacob M, Christensen, Søren T   +3 more
openaire   +3 more sources

The role of primary cilia and sonic hedgehog signalling in adrenal development function. [PDF]

, 2012
PhDPrimary cilia are sensory organelles found on most vertebrate cells during interphase. They play key roles in development, cell signalling and cancer, and are involved in signal transduction pathways such as Hh and Wnt signalling.
Cogger, Kathryn
core   +4 more sources

Recent advances in primary cilia in bone metabolism

Frontiers in Endocrinology, 2023
Primary cilia are microtubule-based organelles that are widespread on the cell surface and play a key role in tissue development and homeostasis by sensing and transducing various signaling pathways.
Fenfen Lian, Hui Li, Yuwei Ma, Rui Zhou, Wei Wu   +4 more
doaj   +1 more source

Methods for studying primary cilia in heart tissue after ischemia-reperfusion injury [PDF]

, 2023
Funding Information: This work was supported by the Agencia Nacional de Investigación y Desarrollo de Chile (ANID, Chile): FONDECYT [1200499 to E.M., 1191078 to R.T., 11181000 to J.A.R. and 1211329 to A.C., 1200490 to S.L]; PIA-ANID [ACT172066 to R.T., E.
Lavandero, Sergio, Criollo, Alfredo, Universidad San Sebastián, Riquelme, Jaime A., Peña-Oyarzún, Daniel, Hill, Joseph A., Bravo-San Pedro, José Manuel, Díaz-Castro, Francisco, Galluzzi, Lorenzo, Reyes, Montserrat, Budini, Mauricio, García-Navarrete, Camila, Hernández-Cáceres, María Paz, Morselli, Eugenia, Kretschmar, Catalina, Troncoso, Rodrigo   +15 more
core   +2 more sources

Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults

Molecular Brain, 2020
Primary cilia are centriole-derived sensory organelles that are present in most mammalian cells, including astrocytes and neurons. Evidence is emerging that astrocyte and neuronal primary cilia demonstrate a dichotomy in the mature mouse brain.
Ashley Sterpka, Juan Yang, Matthew Strobel, Yuxin Zhou, Connor Pauplis, Xuanmao Chen   +5 more
doaj   +1 more source

Primary Cilia Dysfunction in Neurodevelopmental Disorders beyond Ciliopathies

Journal of Developmental Biology, 2022
Primary cilia are specialized, microtubule-based structures projecting from the surface of most mammalian cells. These organelles are thought to primarily act as signaling hubs and sensors, receiving and integrating extracellular cues.
Vasiliki Karalis, Kathleen E. Donovan, Mustafa Sahin   +2 more
doaj   +1 more source

Calcium channels in primary cilia [PDF]

Current Opinion in Nephrology and Hypertension, 2016
Primary cilia have become important organelles implicated in embryonic development, organogenesis, health, and diseases. Although many studies in cell biology have focused on changes in ciliary length or ciliogenesis, the most common readout for evaluating ciliary function is intracellular calcium.Recent tools have allowed us to examine intracellular ...
Surya M, Nauli, Rajasekharreddy, Pala, Steven J, Kleene   +2 more
openaire   +2 more sources

Primary cilia: a novel research approach to overcome anticancer drug resistance

Frontiers in Molecular Biosciences, 2023
Primary cilia are cellular organelles that consist of a microtubule skeleton surrounded by a membrane filled with cell signaling receptors. Many studies have shown that primary cilia are cellular antennas, which serve as signaling hubs and their assembly
Kyung Ho Lee, Kyung Ho Lee
doaj   +1 more source