Results 31 to 40 of about 42,278 (249)

Bardet-Biedl syndrome proteins control cilia length through regulation of actin polymerisation. [PDF]

, 2012
Primary cilia are cellular appendages important for signal transduction and sensing the environment. Bardet-Biedl syndrome proteins form a complex that is important for several cytoskeleton-related processes such as ciliogenesis, cell migration and ...
D Jenkins, PL Beales, Knight, M, Helen May-Simera, Dagan Jenkins, Anna Diaz-Font, Philip L. Beales, Beales, PL, H May-Simera, Diaz-Font, A, Pravincumar, P, A Diaz-Font, Hernandez-Hernandez, V, May-Simera, H, V Hernandez, P Pravincumar, Victor Hernandez-Hernandez, Priyanka Pravincumar, Jenkins, D, M Knight, Martin Knight   +20 more
core   +1 more source

Ionizing radiation promotes primary ciliogenesis in glioblastoma cells

Fushe yanjiu yu fushe gongyi xuebao, 2021
The aim of this study was to investigate the effects of ionizing radiation (IR) on ciliogenesis of human glioblastoma cells. The glioblastoma cell lines M059K and M059J were exposed to X-ray or carbon ion at different doses, and the incidence and length ...
MA Wei, MA Qinglong, WEI Li, HUA Junrui, HE Jinpeng, WANG Jufang   +5 more
doaj   +1 more source

Cep164, a novel centriole appendage protein required for primary cilium formation [PDF]

, 2007
Primary cilia (PC) function as microtubule-based sensory antennae projecting from the surface of many eukaryotic cells. They play important roles in mechano- and chemosensory perception and their dysfunction is implicated in developmental disorders and ...
Graser, Susanne, Erich A. Nigg, Gassner, Oliver S., Gassner, O. S., Susanne Graser, Stierhof, Y. D., Lavoie, S. B., Stierhof, York-Dieter, Nigg, E. A., Sébastien B. Lavoie, Le Clech, M., Stefan Lamla, Graser, S., Nigg, Erich A., Lavoie, Sébastien B., York-Dieter Stierhof, Le Clech, Mikael, Oliver S. Gassner, Mikael Le Clech, Lamla, S., Lamla, Stefan   +20 more
core   +1 more source

Methods for studying primary cilia in heart tissue after ischemia-reperfusion injury

, 2023
Funding Information: This work was supported by the Agencia Nacional de Investigación y Desarrollo de Chile (ANID, Chile): FONDECYT [1200499 to E.M., 1191078 to R.T., 11181000 to J.A.R. and 1211329 to A.C., 1200490 to S.L]; PIA-ANID [ACT172066 to R.T., E.
Lavandero, Sergio, Criollo, Alfredo, Universidad San Sebastián, Riquelme, Jaime A., Peña-Oyarzún, Daniel, Hill, Joseph A., Bravo-San Pedro, José Manuel, Díaz-Castro, Francisco, Galluzzi, Lorenzo, Reyes, Montserrat, Budini, Mauricio, García-Navarrete, Camila, Hernández-Cáceres, María Paz, Morselli, Eugenia, Kretschmar, Catalina, Troncoso, Rodrigo   +15 more
core   +1 more source

Research progress on the distribution of primary cilia and related signaling pathways involved in odontogenesis

口腔疾病防治, 2020
Primary cilia are organelles present on most mammalian cells that sense environmental changes and transduce signaling, and they are the key coordinators of various signaling pathways during tissue development.
ZHOU Tao, WU Peiyao, YANG Yuqing, CAO Zhiwei, XIE Liang   +4 more
doaj   +1 more source

Primary cilia are lost in preinvasive and invasive prostate cancer. [PDF]

PLoS ONE, 2013
Prostate cancer is the second most commonly diagnosed cancer in men worldwide. Little is known about the role of primary cilia in preinvasive and invasive prostate cancer.
Nadia B Hassounah, Ray Nagle, Kathylynn Saboda, Denise J Roe, Bruce L Dalkin, Kimberly M McDermott   +5 more
doaj   +1 more source

Primary Cilia in Glial Cells: An Oasis in the Journey to Overcoming Neurodegenerative Diseases

Frontiers in Neuroscience, 2021
Many neurodegenerative diseases have been associated with defects in primary cilia, which are cellular organelles involved in diverse cellular processes and homeostasis.
Soo Mi Ki, Hui Su Jeong, Ji Eun Lee, Ji Eun Lee   +3 more
doaj   +1 more source

Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm. [PDF]

, 2013
Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous ciliopathy disorder affecting cilia and sperm motility. A range of ultrastructural defects of the axoneme underlie the disease, which is characterised by chronic respiratory symptoms ...
Danke-Roelse, JE, Hart, S.L., Munye, Mustafa M., Scambler, PJ, Rosser, E.M., Hart, Stephen L, Beales, Philip L, Bacchelli, C, Moore, Anthony T., Chung, Eddie MK, Sloper, John J, Danke-Roelse, Jeannette E, Moore, A.T., Pals, Gerard, Beales, Philip L., Sloper, John J., Moore, Anthony T, Hogg, C, Hogg, C., Bacchelli, Chiara, Mitchison, Hannah M, Shoemark, A., Moore, AT, James, C.T., Scambler, Peter J, Chung, E.M.K., Rosser, Elisabeth M., Bacchelli, C., Shoemark, Amelia; id_orcid, Patel, M., Hogg, Claire, Onoufriadis, Alexandros, Schmidts, Miriam, Emes, R.D., Munye, Mustafa M, Hull, S., Sloper, JJ, Hull, Sarah, Beales, PL, Beales, P.L., Hart, Stephen L., Munye, MM, Schmidts, M, James, Chela T, Scambler, P.J., James, Chela T., Mitchison, H.M., nke-Roelse, J.E., Hull, S, Onoufriadis, A., Rosser, Elisabeth M, Emes, Richard D., Patel, Mitali, Pals, G., Mitchison, Hannah M., Patel, M, Pals, G, Emes, RD, Munye, M.M., James, CT, Schmidts, M., Danke-Roelse, Jeannette E., Chung, Eddie M.K., Shoemark, Amelia, Mitchison, HM, Emes, Richard D, Chung, EM, Shoemark, A, Onoufriadis, A, Sloper, J.J., Hart, SL, Rosser, EM, Scambler, Peter J.   +72 more
core   +1 more source

Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation [PDF]

, 2015
Funded by Marie Curie Intra European Fellowship (GENOMICDIFF) Wellcome Trust ...
Thorpe, SD, Connelly, JT, Dalbay, MT, Chapple, JP, Knight, MM   +4 more
core   +1 more source

Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans [PDF]

, 2006
The diversity of sensory cilia on Caenorhabditis elegans neurons allows the animal to detect a variety of sensory stimuli. Sensory cilia are assembled by intraflagellar transport (IFT) kinesins, which transport ciliary precursors, bound to IFT particles,
James E. Evans, Kent L. McDonald, Amy L. Gunnarson, Gunnarson, Amy L., Guangshuo Ou, Snow, JJ, McDonald, KL, Stahlberg, Henning, Ou, Guangshuo, Ou, GS, Evans, JE, Stahlberg, H, Evans, James E., Jonathan M. Scholey, Scholey, JM, Gunnarson, AL, McDonald, Kent L., Joshua J. Snow, Henning Stahlberg, Snow, Joshua J., Scholey, Jonathan M.   +20 more
core   +1 more source