Results 31 to 40 of about 37,275 (255)
Visualizing renal primary cilia [PDF]
Nephrology, 2013 AbstractRenal primary cilia are microscopic sensory organelles found on the apical surface of epithelial cells of the nephron and collecting duct. They are based upon a microtubular cytoskeleton, bounded by a specialized membrane, and contain an array of proteins that facilitate their assembly, maintenance and function.
Deane, James +7 more
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Biology Open, 2013 Summary Primary cilia protrude from the cell surface of many cell types in the human body and function as cellular antennae via ciliary membrane localized receptors.
Livana Soetedjo +2 more
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The emerging face of primary cilia [PDF]
genesis, 2011 AbstractPrimary cilia are microtubule‐based organelles that serve as hubs for the transduction of various developmental signaling pathways includingHedgehog, Wnt, FGF, and PDGF. Ciliary dysfunction contributes to a range of disorders, collectively known as the ciliopathies.
Norann A, Zaghloul, Samantha A, Brugmann
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Primary Cilia and Centrosomes in Neocortex Development [PDF]
Frontiers in Neuroscience, 2021 During mammalian brain development, neural stem and progenitor cells generate the neurons for the six-layered neocortex. The proliferative capacity of the different types of progenitor cells within the germinal zones of the developing neocortex is a major determinant for the number of neurons generated. Furthermore, the various modes of progenitor cell
Wilsch-Bräuninger, M., Huttner, W.
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Primary Cilia and the Cell Cycle [PDF]
, 2009 Cilia are microtubule-based structures that protrude from the cell surface and function as sensors for mechanical and chemical environmental cues that regulate cellular differentiation or division. In metazoans, ciliary signaling is important during organismal development and in the homeostasis controls of adult tissues, with receptors for the Hedgehog,
Olga V, Plotnikova +2 more
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Role of Primary Cilia in Odontogenesis [PDF]
Journal of Dental Research, 2017 Primary cilium is a solitary organelle that emanates from the surface of most postmitotic mammalian cells and serves as a sensory organelle, transmitting the mechanical and chemical cues to the cell. Primary cilia are key coordinators of various signaling pathways during development and maintenance of tissue homeostasis.
M, Hampl +6 more
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口腔疾病防治, 2020 Primary cilia are organelles present on most mammalian cells that sense environmental changes and transduce signaling, and they are the key coordinators of various signaling pathways during tissue development.
ZHOU Tao +4 more
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Primary cilia are lost in preinvasive and invasive prostate cancer. [PDF]
PLoS ONE, 2013 Prostate cancer is the second most commonly diagnosed cancer in men worldwide. Little is known about the role of primary cilia in preinvasive and invasive prostate cancer.
Nadia B Hassounah +5 more
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Primary Cilia in Glial Cells: An Oasis in the Journey to Overcoming Neurodegenerative Diseases
Frontiers in Neuroscience, 2021 Many neurodegenerative diseases have been associated with defects in primary cilia, which are cellular organelles involved in diverse cellular processes and homeostasis.
Soo Mi Ki +3 more
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Ionizing radiation promotes primary ciliogenesis in glioblastoma cells
Fushe yanjiu yu fushe gongyi xuebao, 2021 The aim of this study was to investigate the effects of ionizing radiation (IR) on ciliogenesis of human glioblastoma cells. The glioblastoma cell lines M059K and M059J were exposed to X-ray or carbon ion at different doses, and the incidence and length ...
MA Wei +5 more
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