Results 51 to 60 of about 37,275 (255)

Regulation of primary cilia formation by ceramide [PDF]

Journal of Lipid Research, 2009
The primary cilium is an important sensory organelle, the regulation of which is not fully understood. We found that in polarized Madin-Darby Canine Kidney cells, the sphingolipid ceramide is specifically distributed to a cis-Golgi compartment at the base of the primary cilium. This compartment immunostained for the centrosome marker gamma-tubulin, the
Guanghu Wang, Kannan Krishnamurthy, Erhard Bieberich   +2 more
openaire   +3 more sources

Primary Cilia and Calcium Signaling Interactions [PDF]

International Journal of Molecular Sciences, 2020
The calcium ion (Ca2+) is a diverse secondary messenger with a near-ubiquitous role in a vast array of cellular processes. Cilia are present on nearly every cell type in either a motile or non-motile form; motile cilia generate fluid flow needed for a variety of biological processes, such as left–right body patterning during development, while non ...
Hannah Saternos, Sidney Ley, Wissam AbouAlaiwi   +2 more
openaire   +2 more sources

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Characterization of astrocytic primary cilia in the adult mouse cortex and hippocampus

Heliyon
The primary cilium is a single, antenna-like projection found on the surface of eukaryotic cells. Primary cilia contain cell signaling components that are critical for developmental patterning and cell cycle maintenance.
Sylvie C. Lahaie, Albert HK. Fok, Jessica M. Nicholls, Hannah Lee, Tabish A. Syed, Sabrina Chierzi, Sayuri Hatada, Naomi Egawa, Alex L. Schober, Tak Yi Mayumi Wong, Robert Royston, Jr., Kaleem Siddiqi, Yoshiyuki Kubota, Keith K. Murai   +13 more
doaj   +1 more source

Primary Cilia Are Critical Regulators of White Adipose Tissue Expansion

Frontiers in Physiology, 2021
The primary cilium is a microtubule-based cellular protrusion found on most mammalian cell types in diverse tissues. It functions as a cellular antenna to sense and transduce a broad range of signals, including odorants, light, mechanical stimuli, and ...
Keren I. Hilgendorf
doaj   +1 more source

Role of Primary Cilia in Skeletal Disorders

Stem Cells International, 2022
Primary cilia are highly conserved microtubule-based organelles that project from the cell surface into the extracellular environment and play important roles in mechanosensation, mechanotransduction, polarity maintenance, and cell behaviors during organ development and pathological changes.
Xinhua Li, Song Guo, Yang Su, Jiawei Lu, Donghua Hang, Shao Cao, Qiang Fu, Ziqing Li   +7 more
openaire   +3 more sources

Flexible Dielectric Acoustic Resonator Patch for Tissue Regeneration

Advanced Materials, EarlyView.
A flexible dielectric acoustic resonator patch enables MHz‐range ultrasound generation through resonance amplification without using piezoelectric materials. Conformal integration on a curved substrate allows efficient acoustic delivery to tissue‐mimicking environments.
Donyoung Kang, Byeongseok Ryu, Sujeong Ahn, Junhyub Kim, Myeonghun Jang, Jeong Ho Cho, Won‐Gun Koh, Hyungsuk Lee   +7 more
wiley   +1 more source

Recent Advances of Slip Sensors for Smart Robotics

Advanced Materials Technologies, EarlyView.
This review summarizes recent progress in robotic slip sensors across mechanical, electrical, thermal, optical, magnetic, and acoustic mechanisms, offering a comprehensive reference for the selection of slip sensors in robotic applications. In addition, current challenges and emerging trends are identified to advance the development of robust, adaptive,
Xingyu Zhang, Liao Wu, Shuai He, Zhao Sha, Yuwan Huang, Shuying Wu, Dewei Chu, Chun H. Wang, Shuhua Peng   +8 more
wiley   +1 more source

Primary cilia and forebrain development

Mechanisms of Development, 2013
With a microtubule-based axoneme supporting its plasma membrane-ensheathed projection from the basal body of almost all cell types in the human body, and present in only one copy per cell, the primary cilium can be considered an organelle sui generis.
Willaredt, Marc August, Tasouri, Evangelia, Tucker, Kerry L.   +2 more
openaire   +2 more sources

Multimodal Haptic Perception Through Synergistic Nanocomposite Sensor Arrays

Advanced Materials Technologies, EarlyView.
Multi‐modal fingertip haptics are advanced through a bioinspired &vertical‐via' electronic skin architecture. A confined PDMS/MWCNT/NiNP nanocomposite, sitting at the percolation threshold, enables tactile, thermal, and magnetic sensing. A unique via‐density gradient and dedicated &Un‐Touch' reference nodes provide robust spatial resolution and signal ...
Amos Bardea, Fernando Patolsky
wiley   +1 more source