Results 11 to 20 of about 37,275 (255)
Primary cilia and lipid raft dynamics [PDF]
Open Biology, 2021 Primary cilia, antenna-like structures of the plasma membrane, detect various extracellular cues and transduce signals into the cell to regulate a wide range of functions.
Yuhei Nishimura +5 more
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Rediscovering Primary Cilia in Pancreatic Islets [PDF]
Diabetes & Metabolism Journal, 2023 Primary cilia are microtubule-based sensory and signaling organelles on the surfaces of most eukaryotic cells. Despite their early description by microscopy studies, islet cilia had not been examined in the functional context until recent decades.
Eun Young Lee, Jing W. Hughes
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NRF2 and Primary Cilia: An Emerging Partnership [PDF]
Antioxidants, 2020 When not dividing, many cell types target their centrosome to the plasma membrane, where it nucleates assembly of a primary cilium, an antenna-like signaling structure consisting of nine concentric microtubule pairs surrounded by membrane.
Ana Martin-Hurtado +3 more
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Emerging Roles of Primary Cilia in Glioma [PDF]
Frontiers in Cellular Neuroscience, 2019 Primary cilia are microtubule-based organelles that are typically present on cells during the G0 or G1-S/G2 phases of the cell cycle. Recent studies of glioblastoma (GBM) biopsies, a brain tumor that is notorious for its aggressive growth and resistance ...
Matthew R. Sarkisian +2 more
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Primary Cilia and Atherosclerosis [PDF]
Frontiers in Physiology, 2021 In artery tree, endothelial function correlates with the distribution of shear stress, a dragging force generated by flowing blood. In laminar shear stress areas, endothelial cells (ECs) are available to prevent atherosclerosis, however, ECs in disturbed shear stress sites are featured with proinflammation and atherogenesis.
Zhi-Mei Wang +3 more
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Current Osteoporosis Reports, 2023 Abstract Purpose of Review The purpose of this review is to provide a background on osteocytes and the primary cilium, discussing the role it plays in osteocyte mechanosensing. Recent Findings Osteocytes are thought to be the primary mechanosensing cells in bone tissue ...
Verbruggen, S.W. +2 more
openaire +4 more sources
Vaping in Asthmatic Adolescents: Time to Deal with the Elephant in the Room
Children, 2022 Adolescence is a period characterized by developmental, psychological, and psychosocial alterations, with a major impact on youths’ attitudes and perceptions.
Grigorios Chatziparasidis, Ahmad Kantar
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Assembly of primary cilia [PDF]
Developmental Dynamics, 2008 AbstractPrimary cilia are microtubule‐based, hair‐like sensory organelles present on the surface of most growth‐arrested cells in our body. Recent research has demonstrated a crucial role for primary cilia in regulating vertebrate developmental pathways and tissue homeostasis, and defects in genes involved in primary cilia assembly or function have ...
Pedersen, Lotte B +3 more
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Lengthening primary cilia enhances cellular mechanosensitivity [PDF]
European Cells & Materials, 2017 The primary cilium is a mechanosensor in a variety of mammalian cell types, initiating and directing intracellular signalling cascades in response to external stimuli.
M Spasic, CR Jacobs
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Recent advances in primary cilia in bone metabolism
Frontiers in Endocrinology, 2023 Primary cilia are microtubule-based organelles that are widespread on the cell surface and play a key role in tissue development and homeostasis by sensing and transducing various signaling pathways.
Fenfen Lian +4 more
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